Epigenetic treatments: New allies for chemotherapies?
Though chemotherapies are effective in some patients, tumour cells may acquire tolerance to these treatments. In other words, cells adapt to chemotherapy so they can survive. A new study delivers promising results on epigenetic mechanisms that regula.....»»
Squishy microgels in granular biomaterials confine and direct cell behavior
A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State......»»
Improved lipid-polymer nanoparticle could advance inhalable mRNA medications and vaccines
Most people don't enjoy getting shots for treatments or vaccines. So, researchers are working to create more medicines, such as those made from messenger RNA (mRNA), that can be sprayed and inhaled......»»
A causal theory for studying the cause-and-effect relationships of genes paves the way for targeted treatments
By studying changes in gene expression, researchers learn how cells function at a molecular level, which could help them understand the development of certain diseases......»»
Ukraine"s Zelenskyy urges allies to act before North Korean troops reach the front
Ukraine"s Zelenskyy urges allies to act before North Korean troops reach the front.....»»
Discovery of new bacterial toxins could be key to fighting infections
Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments for infections. These toxins, found in over 100,000 microbial genomes, can destroy the cells of bacteri.....»»
Targeting "selfish" bacteria could optimize inhibitors that fight antibiotic resistance
As strains of pathogens resistant to frontline antibiotics become more common worldwide, clinicians are more often turning to combination treatments that degrade this resistance as a first treatment option......»»
New nanotherapy targets artery inflammation in cardiovascular disease
Inflammation of the arteries is a primary precursor and driver of cardiovascular disease—the No. 1 killer of people in the United States. This inflammation is associated with the buildup of dangerous plaque inside the arteries. Advanced treatments.....»»
Scientists discover novel series of SARS-CoV-2 Mpro inhibitors for potential new COVID-19 treatments
New research from The Wistar Institute's Salvino lab, led by professor Joseph Salvino, Ph.D., has identified a novel series of SARS-CoV-2 Mpro inhibitors that may lead to potential new COVID-19 treatments that—according to preclinical testing—eff.....»»
Artificial proteasome offers insights for new trichomoniasis treatments
Researchers from IOCB Prague are furthering the understanding of how medicines work and what it takes to develop their most effective variants. In one current study, they have focused on the disease caused by the protozoan parasite Trichomonas vagina.....»»
Trees" own beneficial microbiome could lead to discovery of new treatments to fight citrus greening disease
Citrus trees showing natural tolerance to citrus greening disease host bacteria that produce novel antimicrobials that can be used to fight off the disease, our recent study shows. We found the trees at an organic farm in Clermont, Florida......»»
Protein involved in the early stages of age-related macular degeneration offers hope for prevention
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the United States. Despite existing treatments, the underlying causes of this disease and effective therapies remain elusive. Research published in the journal D.....»»
High-resolution images of RSV may expose stubborn virus"s weak points
The complex shape of respiratory syncytial virus (RSV) is one hurdle limiting the development of treatments for an infection that leads to hospitalization or worse for hundreds of thousands of people in the United States each year, according to the C.....»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
Strange Visual Auras Could Hold the Key to Better Migraine Treatments
Research on the visual patterns that foreshadow migraines may reveal clues on how painful headaches arise from the brain even though it has no pain receptors......»»
Harnessing nature"s rhythm: Piezocatalysis for organic pollutant degradation
With the rapid growth of industrial and agricultural activities, water bodies are increasingly contaminated with harmful organic pollutants such as dyes, antibiotics, and bisphenol A. Traditional methods like adsorption, chemical treatments, and biol.....»»
Scientists find new epigenetic switch, revealing how genes are regulated in early development
The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early emb.....»»
New Sickle Cell Treatments Reach Patients after Years of Effort
The FDA recently approved three sickle cell drugs, and dozens more are in development.....»»
New Treatments Address Addiction alongside Trauma
A new generation of treatments addresses the trauma that often underlies addiction.....»»
New Sickle Cell Treatments Highlight the Power of Patient Perspectives
Illuminating the experience of people living with sickle cell could improve patients’ lives and enhance all of medicine.....»»
What is reproductive health leave and why do we need it?
Time off work to deal with IVF, menopause, gender transition treatments, vasectomies and other reproductive health issues would be enshrined in all workplace awards if a national union campaign succeeds......»»