Embryo blood cells are stem cell–independent
The fetal liver is the major hematopoietic organ during the embryonic stage. It is generally believed that hematopoietic hierarchy in the fetal liver is established through the differentiation of fetal hematopoietic stem cells (HSCs). This view assum.....»»
The First Crispr Treatment Is Making Its Way to Patients
It’s been a year since the gene-editing treatment Casgevy was approved for sickle cell disease and a related blood disorder. It’s finally being infused into patients......»»
Using genetic code expansion to study membrane proteins
Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it possible to modify proteins directly in living cells to giv.....»»
Picky proteins: Understanding yeast adaptor protein selectivity
The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis......»»
Bone Marrow Donors Can Be Hard to Find. One Company Is Turning to Cadavers
San Francisco–based Ossium Health has carried out three transplants for cancer patients using stem cells from deceased donors’ bone marrow in recent months......»»
Researchers Give Animal Cells the Ability to Photosynthesize for the First Time
A Japanese team has developed a technique to insert chloroplasts isolated from algae into animal cells, a feat that could revolutionize sustainable energy and how artificial meat and organs are created......»»
Squishy microgels in granular biomaterials confine and direct cell behavior
A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State......»»
Deals: M4 MacBook Pro hits all-time low at $125 off, GPS+Cell Apple Watch Series 10 $50 off, Alpine Loops, more
Joining all-time lows on the 42mm and 46mm Apple Watch Series 10 starting from $349, today Amazon has decided to carry the deep discounts over to the GPS+Cell models, including both the aluminum and higher-end titanium variants starting at $449 (the.....»»
Researchers identify two primary tree movement patterns that help them survive high winds and prevent damage
Destructive winds during storms and cyclones often cause tree failures, especially through uprooting and stem breakage. However, how trees respond to wind under various forest configurations and weather conditions remains unclear......»»
High-performance inkjet print head enhances bioprinting productivity
Bioprinting is a technology used to create three-dimensional structures, such as human tissues or organs, using bio-inks made of cells and hydrogels. However, conventional inkjet technology has difficulty dispensing bio-inks that are sensitive to tem.....»»
Using CRISPR to decipher whether gene variants lead to cancer
In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the genetic material of living organisms. One application is in cell therapy: A patient's immune cells can be specifically reprogramm.....»»
New CRISPR system for gene silencing doesn"t rely on cutting DNA
Scientists from Vilnius University's (VU) Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA. This research, led by Prof. Patrick Pausch and published in the journal Nature Communications,.....»»
Beach kindergarten helps kids grasp early STEM concepts
Deakin University research has for the first time observed the science, technology, engineering and math (STEM) learning benefits of 'blue space' education settings for pre-school aged children......»»
Leeches are making a medical comeback—here"s why we should celebrate it
As we tidy away the Dracula capes and glow-in-the-dark plastic fangs for another winter, one notorious blood sucker has had a particularly good year......»»
Mitochondrial study offers new insights into how our cells process RNA for energy production
Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have made a major discovery in how human cells produce energy. Their study, published in The EMBO Journal, reveals the detailed mechanisms of how mitochondria process.....»»
Man sick of crashes sues Intel for allegedly hiding CPU defects
Intel’s faulty 13th- and 14th-gen CPUs trigger lawsuit out for blood. One frustrated customer wants to force Intel to pay untold millions in damages, claiming the company decept.....»»
A causal theory for studying the cause-and-effect relationships of genes paves the way for targeted treatments
By studying changes in gene expression, researchers learn how cells function at a molecular level, which could help them understand the development of certain diseases......»»
Team develops non-invasive biosensor for early kidney disease detection
Traditionally, kidney health has been monitored by measuring blood creatinine levels, which indicate muscle breakdown. High creatinine levels can suggest that the kidneys are not filtering waste efficiently. However, creatinine levels can be affected.....»»
Vampire bats" metabolism mirrors that of blood-sucking insects, biologists find
A pair of biologists at the University of Toronto has found that vampire bats are able to burn amino acids as a fuel source similarly to blood-sucking insects. In their study published in the journal Biology Letters, Giulia Rossi and Kenneth Welch co.....»»
Cells have more mini "organs" than once thought—these rogue organelles challenge biology"s fundamentals
Think back to that basic biology class you took in high school. You probably learned about organelles, those little "organs" inside cells that form compartments with individual functions. For example, mitochondria produce energy, lysosomes recycle wa.....»»
Researchers uncover focal adhesions as subcellular signaling hubs in PI3K-AKT pathway
The phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central regulator of various cellular processes including cell growth, proliferation, metabolism, an.....»»