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Efficiently smuggling drugs into cells

A new, patented method called Progressive Mechanoporation makes it possible to mechanically disrupt the membranes of cells for a short time period and let drugs or genes inside cells. In this way, researchers can test new therapies more easily than b.....»»

Category: topSource:  physorgMay 12th, 2021

Plant stem cells: Understanding the biological mechanism of growth control

Researchers from the University of Freiburg have identified the HAN molecule as an important regulator that controls plant growth in conjunction with WOX5. Understanding this mechanism is relevant for breeding more resilient or higher-yielding crops......»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

Expansion technique to image nanoscale structures inside cells makes high-resolution imaging more accessible

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before imaging it—a technique that allows them to achieve.....»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

Claustrophobic cells slow their own growth, forming beautiful patterns of concentric circles

Like so many organisms on the planet, when cells experience mosh-pit-level crowding, they may just become stressed. Yet unlike most other life forms, cells subject to physical stress from crowding by neighbors can find some relief by dramatically slo.....»»

Category: topSource:  informationweekRelated NewsOct 10th, 2024

Advanced model predicts gene architecture via nucleosome position

DNA—the molecule that carries the genetic information of all living organisms—is packaged within cells in a complex manner that allows it to function efficiently. Nucleosomes facilitate DNA compaction and also play a crucial role in regulating ge.....»»

Category: topSource:  informationweekRelated NewsOct 10th, 2024

From chaos to structure: How a bunch of seemingly disorganized cells go on to form a robust embryo

Pipetting liquids into tiny test tubes, analyzing huge datasets, poring over research publications—all these tasks are part of being a scientist. But breaking this routine is essential. Time away from the usual work environment can spark creative i.....»»

Category: topSource:  theglobeandmailRelated NewsOct 10th, 2024

Drug makers can’t make knockoff weight-loss drugs anymore—and they’re mad

Compounding pharmacies could make knockoffs during shortage. But FDA says it's over. Compounding pharmacies are suing the Food and Drug Administration so they can keep making imit.....»»

Category: topSource:  arstechnicaRelated NewsOct 10th, 2024

How Chlamydia pneumoniae bacteria use molecular mimicry to manipulate the host cell

Bacteria that cause diseases, so-called pathogens, develop various strategies to exploit human cells as hosts to their own advantage. A team of biologists from Heinrich Heine University Düsseldorf (HHU), together with medical professionals and exper.....»»

Category: topSource:  physorgRelated NewsOct 9th, 2024

Cryo-electron microscopy provides new insights into the cell"s repair system

The membrane that surrounds cells in living organisms is extremely flexible and sensitive. How it protects itself from damage and renews itself is crucial for many life processes, and is not yet fully understood in detail. Scientists at Forschungszen.....»»

Category: topSource:  physorgRelated NewsOct 8th, 2024

Researchers design a drug capable of acting simultaneously against three different therapeutic targets

A study led by researchers of the Institute of Biomedicine of the University of Barcelona (IBUB) has developed a new pharmacological tool capable of simultaneously administering three oligonucleotide-based drugs, each acting against a different thera.....»»

Category: topSource:  physorgRelated NewsOct 8th, 2024

Nanopore technique shows transport mechanism of chaperone proteins at the single-molecule level

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality......»»

Category: topSource:  physorgRelated NewsOct 8th, 2024

Single-celled eukaryote employs unconventional cytoskeletal components for dynamic shape-shifting

Recently, a research group led by Prof. Miao Wei from the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences discovered that Lacrymaria cells utilize unconventional and novel components of the cytoskeleton to achieve their remarkable.....»»

Category: topSource:  physorgRelated NewsOct 8th, 2024

Cancer, cardiovascular drugs tipped for Nobel as prize week opens

Cancer research or drugs treating cardiovascular illnesses could win a Nobel Prize on Monday when a week of laureate announcements kicks off, bringing a ray of optimism to a world beset by crises......»»

Category: topSource:  informationweekRelated NewsOct 7th, 2024

Dead Cells follow-up Windblown already feels like a roguelike classic

Dead Cells follow-up Windblown is heading into early access later this month and it's already feeling spectacular......»»

Category: topSource:  digitaltrendsRelated NewsOct 3rd, 2024

Quantum researchers come up with a recipe that could accelerate drug development

University of Copenhagen mathematicians have developed a recipe for upgrading quantum computers to simulate complex quantum systems, such as molecules. Their discovery brings us closer to being able to predict how new drugs will behave within our bod.....»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

Engineers create a chip-based tractor beam for biological particles

MIT researchers have developed a miniature, chip-based "tractor beam," like the one that captures the Millennium Falcon in the film "Star Wars," that could someday help biologists and clinicians study DNA, classify cells, and investigate the mechanis.....»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

Tesla plans four new batteries in 2026, including for robotaxi, The Information reports

Tesla plans four new batteries in 2026. Tesla sources most of its EV batteries from other companies, including Panasonic Energy and LG Energy but wants to ramp up production of its 4680 battery cells......»»

Category: topSource:  autonewsRelated NewsOct 3rd, 2024

Scientists find plant-like behavior in human cells

A team of scientists from Monash University has solved the structure of a protein known as "LYCHOS," which can detect and regulate cell growth by sensing cholesterol levels in the body......»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

As the Advanced Photon Source upgrade nears completion, scientists anticipate experimental possibilities

In June, X-rays began to shine again at the U.S. Department of Energy's (DOE) Advanced Photon Source (APS), a facility where intense, directed X-ray light beams are used to inspect everything from materials for better solar cells and batteries to ant.....»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

These Record-Breaking New Solar Panels Produce 60 Percent More Electricity

Experimental cells that combine silicon with a material called perovskite have broken the efficiency record for converting solar energy—and could eventually supercharge how we get electricity......»»

Category: gadgetSource:  wiredRelated NewsOct 2nd, 2024

First-ever artificial cell nuclei created in living egg from purified DNA injection

A research group is the first in the world to succeed in constructing artificial cell nuclei by injecting purified DNA solution instead of sperm into living mouse eggs. Their findings are published in the journal Genes to Cells......»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024