Drug is promising against pancreatic and breast cancers
The drug is effective at treating pancreatic cancer and prolonging survival in mice, according to a new study. A second study shows the drug is also effective against triple-negative breast cancer, a fast-growing and hard-to-treat type of breast canc.....»»
Protein prediction technology yields accurate results to efficiently find the best drug candidate for many conditions
Artificial intelligence (AI) has numerous applications in health care, from analyzing medical imaging to optimizing the execution of clinical trials, and even facilitating drug discovery......»»
A rethink of diseases in light of phase separation and phase transition may be necessary
A review delves into the significance of biomolecular condensation in cellular processes, the impact of aberrant phase separation on diseases such as neurodegenerative diseases, cancers, and infectious diseases, and the potential for manipulating pha.....»»
Wegovy Can Keep Weight Off for at Least 4 Years, Research Shows
Users receiving weekly injections saw their weight fall, plateau, and stabilize over the course of a four-year trial—but it’s still unclear how long these effects last after stopping taking the drug......»»
Data-driven model rapidly predicts dehydrogenation barriers in solid-state materials
Researchers have developed a data-driven model to predict the dehydrogenation barriers of magnesium hydride (MgH2), a promising material for solid-state hydrogen storage. This advancement holds significant potential for enhancing hydrogen storage tec.....»»
Research identifies mechanism behind drug resistance in malaria parasite
Collaborating researchers have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs—specifically artemisinin (ART)—through a cellular process called transfer ribonucleic acid (tRNA) modification. tRNA m.....»»
Researchers discover new family of bacteria with high pharmaceutical potential
Most antibiotics used in human medicine originate from natural products derived from bacteria and other microbes. Novel microorganisms are therefore a promising source of new active compounds, also for the treatment of diseases such as cancer or vira.....»»
Heating proteins to body temperature reveals new drug targets
Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications, new research has found......»»
Nanoparticle plant virus treatment shows promise in fighting metastatic cancers in mice
An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, according to a new study from the University of California San Diego......»»
Doctor Who review: a promising era, but a rocky start
Doctor Who kicks off its promising new era with a pair of surprisingly forgettable episodes......»»
Chemical tweaks to a toad hallucinogen turns it into a potential drug
Targets a different serotonin receptor from other popular hallucinogens. Enlarge / The Colorado River toad, also known as the Sonoran Desert Toad. (credit: Mark Newman) It is becoming increasingly accepted that classic p.....»»
Areas with more illegal market opportunities more likely to be targeted by organized crime, study shows
Communities with higher-than-average illegal market opportunities (proxied by drug-related activities) are more likely to be targeted by organized crime groups, a new study shows......»»
New DNA origami technique promises advances in medicine
A new technique in building DNA structures at a microscopic level has the potential to advance drug delivery and disease diagnosis, a study suggests......»»
For sustainable aviation fuel, researchers engineer a promising microorganism for precursor production
Sustainable aviation fuels made from renewable sources of carbon could reduce carbon dioxide emissions and help to mitigate climate change. Isoprenol is a chemical involved in the production of a jet biofuel blendstock called 1,4-dimethylcyclooctane.....»»
Motorola just launched a new Android phone to take on the Google Pixel 8a
Hot on the heels of the Google Pixel 8a announcement, Motorola just revealed the Moto G Stylus 5G (2024) — and it looks mighty promising......»»
40 years later, Kontrabant 2 for ZX Spectrum is rebroadcast on FM in Slovenia
Celebrating radio waves, magnetic tape heads, and smuggled 8-bit computers. Enlarge / In 1984, the year 2000 was so promising, students made entire games promising to take you there. (credit: Radio Student) Software is.....»»
A multi-stream network for retrosynthesis prediction
Retrosynthesis aims to predict a set of reactants for producing given molecules, which plays a significant part in the biochemistry field, such as molecular pathway design and drug discovery. Most existing methods only benefit from one kind of inform.....»»
Researchers target spermidine production to combat emerging drug resistance in Salmonella
Food-borne diseases like typhoid, caused by Salmonella Typhimurium, are a severe threat to public health, especially in India. The indiscriminate use of antibiotics has allowed this bacterium to become resistant, posing a major hurdle in treating inf.....»»
Researchers map out anatomy of wooden breast syndrome in broiler chickens
Each year, Delaware farms raise more than 240 million broiler chickens, the top agricultural commodity in the state with a $3.5 billion impact on the state's economy......»»
Study underscores new strategies to fight drug-resistant bacteria
Several billion years ago, a genetic arms race began between bacteria and their viral killers. This seemingly eternal struggle continues today, with implications for diseases killing tens of thousands of people around the world each year......»»
Researchers establish commercially viable process for manufacturing with promising new class of metals
Nanostructured high entropy alloys—metals made from a chaotic mix of several different elements—show a lot of promise for use in industries such as aerospace and automotive because of their strength and stability at high temperatures compared wit.....»»