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Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2

ABC transporters constitute a major class of multidrug resistance proteins, e.g., in cancer cells. Membrane lipids have been long known to influence the structure and functional dynamics of these proteins. However, previous structural and biochemical.....»»

Category: topSource:  physorgJan 4th, 2023

Researchers show the link between trawls and climate change in the North Sea

Fishing trawls cause significant CO2 emissions as they stir up the carbon bound in the seabed and release it again. It is also clear that they drastically affect ecosystems in the ocean. A new study by the Helmholtz-Zentrum Hereon models the influenc.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

New study unveils how water dynamics slow down at low temperatures

A scientist at the Institute for Molecular Science has published a study that provides insight into the puzzling phenomenon of dynamic slowdown in supercooled water, an essential step toward understanding the glass transition in liquids......»»

Category: topSource:  physorgRelated NewsMay 28th, 2024

Scientists elucidate substrate recognition and proton coupling mechanism of transporter protein VMAT2

Vesicular monoamine transporter 2 (VMAT2) is the only transporter protein in the central nervous system that mediates the storage of monoamine neurotransmitters. It plays a critical role in mediating nerve impulse transmission and neuroprotection......»»

Category: topSource:  physorgRelated NewsMay 28th, 2024

Personalized phage therapy heals resistant wounds in Siamese cat

A new study has shown an advance in the treatment of antibiotic-resistant infections in animals. The research, focusing on a 5-year-old Siamese cat Squeaks with a multidrug-resistant Pseudomonas aeruginosa infection post-arthrodesis surgery, marks th.....»»

Category: topSource:  physorgRelated NewsMay 27th, 2024

Instagram Users Report Issues In Viewing Stories, Uploading Posts, And Sending Direct Messages

Instagram Users Report Issues In Viewing Stories, Uploading Posts, And Sending Direct Messages.....»»

Category: topSource:  marketingvoxRelated NewsMay 25th, 2024

Researchers reveal how acetylation regulates centromere dynamics, chromosome segregation and mitotic progression

Cell division produces new cells, which underpin life proliferation and development. Mitosis is the shortest and the most dynamic phase of the cell cycle. During mitosis, chromosomes are evenly distributed between the two daughter cells, preserving t.....»»

Category: topSource:  physorgRelated NewsMay 24th, 2024

First topological quantum simulator device in strong light-matter interaction regime to operate at room temperatures

Researchers at Rensselaer Polytechnic Institute have fabricated a device no wider than a human hair that will help physicists investigate the fundamental nature of matter and light. Their findings, published in the journal Nature Nanotechnology, coul.....»»

Category: topSource:  pcmagRelated NewsMay 24th, 2024

Bluesky now finally lets users send and receive DMs

The Bluesky microblogging platform, launched last year, is getting a major update this week. Starting today, users can finally send and receive direct messages (DMs) – a long-awaited feature for those who use Bluesky every day. more….....»»

Category: gadgetSource:  9to5macRelated NewsMay 23rd, 2024

Arc Search for iPhone goes conversational with ‘Call Arc’ feature

Today in the latest update to Arc Search for iPhone, search is becoming more conversational. The new ‘Arc Search’ feature aims to replicate the dynamics of talking on the phone, providing Arc users with a more voice assistant-like experience......»»

Category: gadgetSource:  9to5macRelated NewsMay 23rd, 2024

New insights into the interaction of femtosecond lasers with living tissue

Nonlinear light microscopy has revolutionized our ability to observe and understand complex biological processes. However, light can also damage living matter. Yet, the mechanism behind the irreversible perturbation of cellular processes by intense l.....»»

Category: topSource:  physorgRelated NewsMay 23rd, 2024

Scientists develop novel approach to interrogate tissue-specific protein–protein interactions

Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out.....»»

Category: topSource:  physorgRelated NewsMay 23rd, 2024

Bluesky finally adds a feature many had been waiting for

X rival Bluesky has finally added direct messages to its app, though at the current time they're not end-to-end encrypted......»»

Category: topSource:  digitaltrendsRelated NewsMay 23rd, 2024

A merger of microbes: Study shows low-nutrient conditions alter viral infection

This much we know: When viruses infect bacteria—a common occurrence in oceans, soils, even human guts—the interaction results in the creation of entirely new organisms called "virocells." But scientists are still learning about how this merger of.....»»

Category: topSource:  physorgRelated NewsMay 22nd, 2024

New insights into the degradation dynamics of organic material in the seafloor

The long-term deposition of organic material in sediments on the ocean floor is a key process in the global carbon cycle. The question of whether, from a chemical perspective, the deposited material is more similar to marine algae or the microorganis.....»»

Category: topSource:  physorgRelated NewsMay 22nd, 2024

Promethium bound: New study uncovers rare earth element"s properties

Scientists have uncovered the properties of a rare earth element that was first discovered 80 years ago at the very same laboratory, opening a new pathway for the exploration of elements critical in modern technology, from medicine to space travel......»»

Category: topSource:  theglobeandmailRelated NewsMay 22nd, 2024

Veeam fixes auth bypass flaw in Backup Enterprise Manager (CVE-2024-29849)

Veeam has patched four vulnerabilities in Backup Enterprise Manager (VBEM), one of which (CVE-2024-29849) may allow attackers to bypass authentication and log in to its web interface as any user. With no user interaction required for remote exploitat.....»»

Category: securitySource:  netsecurityRelated NewsMay 22nd, 2024

Study decodes dimerization and antidepressant recognition at noradrenaline transporter

The noradrenaline transporter, also known as the norepinephrine transporter (NET), is a member of the monoamine transporters (MATs) family, which also includes serotonin transporter (SERT) and dopamine transporter (DAT). These transporters collective.....»»

Category: topSource:  physorgRelated NewsMay 21st, 2024

Designing a tiny new tool to map and treat children"s brain cancer

Medulloblastoma is the most common cancerous brain tumor in children, and fighting it requires an approach that is delicate, durable, and direct. Now a group of researchers at UQ's Australian Institute for Bioengineering and Nanotechnology (AIBN) bel.....»»

Category: topSource:  physorgRelated NewsMay 21st, 2024

Decarbonization dynamics: New analysis unveils shifting trends in the voluntary carbon offset market

As humanity grapples with the fight against climate change, reducing greenhouse gas emissions is urgently necessary. One way to achieve this is through the carbon offset market, where organizations or individuals can buy credits from emissions-reduci.....»»

Category: topSource:  physorgRelated NewsMay 20th, 2024

Expanding on the fundamental principles of liquid movement

From the rain drops rolling down your window, to the fluid running through a COVID rapid test, we cannot go a day without observing the world of fluid dynamics. Naturally, how liquids traverse across, and through, surfaces is a heavily researched sub.....»»

Category: topSource:  physorgRelated NewsMay 20th, 2024