Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2
ABC transporters constitute a major class of multidrug resistance proteins, e.g., in cancer cells. Membrane lipids have been long known to influence the structure and functional dynamics of these proteins. However, previous structural and biochemical.....»»
Evolving market dynamics foster consumer inattention that can lead to risky purchases, says researchers
Researchers have developed a new theory of how changing market conditions can lead large numbers of otherwise cautious consumers to buy risky products such as subprime mortgages, cryptocurrency or even cosmetic surgery procedures......»»
Self-determination and social identity: Modeling team motivation
What are the underlying dynamics of group motivation in a team or organization? How does it take shape? And how does it influence a team's functioning and effectiveness?.....»»
Mission control is trying "restlessly" to save a spacecraft to Mercury
A joint European and Japanese spacecraft bound for Mercury has encountered thrust problems that could jeopardize the future of the mission. A complex mission to Mercury that began its epic space voyage six years ago has encountered critical thr.....»»
How "ethical influencers" engage their audiences about saving the planet
Have a quick think back to the last time you scrolled through social media. Maybe it was this morning, last night or a few minutes ago. What do you recall? One thing you're bound to remember is the continuous stream of influencers showing off their l.....»»
Spotify hit with cease and desist from music publishers alleging ‘direct infringement’
Spotify is being accused of engaging in “direct infringement by hosting unlicensed musical works in its lyrics, videos and podcasts” by the National Music Publishers Association. In a new letter sent to the music streaming service this week, the.....»»
Nothing Teases ChatGPT Arrival for its Audio Products
Nothing fans can soon look forward to direct AI access in their ears within this month. The post Nothing Teases ChatGPT Arrival for its Audio Products appeared first on Phandroid. A while back, the launch of the Nothing Ear (a) was accompa.....»»
Ultrasensitive gas detection empowered by synergy of graphene and sub-comb dynamics
Since the inception of microcomb, whose generation relies on Kerr nonlinearity in microresonator, the coherent soliton state has attracted intense research. Although the operation of sub-comb outputs is straightforward, as a noncoherent comb state,.....»»
Researchers elucidate ultrafast laser-induced solid-to-overdense-plasma transitions
The interaction of solids with high-intensity ultra-short laser pulses has enabled major technological breakthroughs over the past half-century. On the one hand, laser ablation of solids offers micromachining and miniaturization of elements in medica.....»»
Every summer 2024 gaming showcase: full schedule of live streams
From Summer Game Fest to this June's Nintendo Direct, here's every major video game showcase happening this summer......»»
Study shows AI conversational agents can help reduce interethnic prejudice during online interactions
Prejudice and fear have always been at the core of intergroup hostilities. While intergroup interaction is a prerequisite for initiating peace and stability at the junction of clashing interests, values, and cultures, the risk of further escalation p.....»»
Tauonium: The smallest and heaviest atom with pure electromagnetic interaction
The hydrogen atom was once considered the simplest atom in nature, composed of a structureless electron and a structured proton. However, as research progressed, scientists discovered a simpler type of atom, consisting of structureless electrons, muo.....»»
Team develops an epigenome editing toolkit to dissect the mechanisms of gene regulation
Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription factors, DNA regulatory regions, and epigenetic mo.....»»
MATE transporter facilitates bitter saponin transport from cytoplasm to vacuole
Domestic soybeans serve as an important source of healthy edible plant oil and high-quality plant protein in our food culture. In addition to the well-known components of oil (approximately 20%), protein (approximately 40%), and carbohydrates (approx.....»»
New study delves into ozone"s influence on exoplanetary climate
In the quest for life beyond our solar system, a new study delves into the atmospheric dynamics of planet Proxima Centauri b, illuminating ozone's pivotal role in shaping planetary climates. This research signifies a significant leap forward in our u.....»»
Study reveals flaw in long-accepted approximation used in water simulations
Computational scientists at the Department of Energy's Oak Ridge National Laboratory have published a study in the Journal of Chemical Theory and Computation that questions a long-accepted factor in simulating the molecular dynamics of water: the 2-f.....»»
7 best 1990s crime movies, ranked
The '90s were an incredible decade for the crime genre, producing acclaimed classics like Pulp Fiction and underappreciated gems like Bound......»»
Nintendo confirms that Switch 2 and a June Direct are coming
Nintendo confirmed it will talk about upcoming Switch games in a Direct this June, as well as its Nintendo Switch successor before the end of the fiscal year......»»
Experiment opens door for millions of qubits on one chip
Researchers from the University of Basel and the NCCR SPIN have achieved the first controllable interaction between two hole spin qubits in a conventional silicon transistor. The breakthrough opens up the possibility of integrating millions of these.....»»
Attosecond core-level spectroscopy reveals real-time molecular dynamics
Chemical reactions are complex mechanisms. Many different dynamic processes are involved, affecting both the electrons and the nucleus of the present atoms. Very often, the strongly coupled electron and nuclear dynamics induce radiation-less relaxati.....»»
Novel chemical tool for understanding membrane remodeling in the cell
In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell......»»