Demonstrating the significance of individual molecules during mechanical stress in cells
The cells in our bodies are continuously exposed to mechanical forces that are either externally applied or generated by the cells themselves. Being able to respond to such mechanical stimuli is an indispensable prerequisite for a large number of bio.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Model highlights three roots of online toxicity
In 2022, Professor of Cognitive Neuroscience Dean Mobbs began to investigate the relationship between social media use and mental health and well-being. As his research program ramps up to test brain activity and physiological markers of stress durin.....»»
Controlling molecular electronics with rigid, ladder-like molecules
As electronic devices continue to get smaller and smaller, physical size limitations are beginning to disrupt the trend of doubling transistor density on silicon-based microchips approximately every two years, according to Moore's law. Molecular elec.....»»
Canada to slap tariffs on EVs, steel from China
Canada, an export-driven economy that relies heavily on trade with the U.S., has been closely watching moves by the Biden administration to erect a much higher tariff wall against Chinese EVs, batteries, solar cells, steel and other products......»»
Physicists ease path to entanglement for quantum sensing
Nothing in science can be achieved or understood without measurement. Today, thanks to advances in quantum sensing, scientists can measure things that were once impossible to even imagine: vibrations of atoms, properties of individual photons, fluctu.....»»
3D-printed living cells pave way for tomorrow"s medicine and cruelty-free animal products
Researchers are expanding the possibilities of 3D printing to create miniature human organs and a variety of products made from living tissue, including food......»»
The promise of synthetic cells
For over a decade, scientists have made extraordinary progress on the long-held dream of fabricating an entire cell from nonliving molecules and materials......»»
Ecosystems study finds the higher the environmental stress, the lower the resistance to global change
An international study led by the Institute of Natural Resources and Agrobiology of Seville (IRNAS-CSIC), of the Spanish National Research Council (CISC), has shown that as the number of global change factors increases, terrestrial ecosystems become.....»»
Ultra-sensitive photothermal microscopy technique detects single nanoparticles as small as 5 nm
The detection of individual particles and molecules has opened new horizons in analytical chemistry, cellular imaging, nanomaterials, and biomedical diagnostics. Traditional single-molecule detection methods rely heavily on fluorescence techniques, w.....»»
As EV sales slump, Volkswagen scales back battery factories buildout
VW might only need 170 GWh of cells in 2030 if demand stays depressed. Enlarge / A VW worker on the assembly line at Emden in Germany. (credit: Volkswagen) Volkswagen will wait to see what electric car demand is like be.....»»
New "chiral vortex" of light allows chemists to "see" molecules through the mirror
An entirely new structure of light is helping to measure chirality in molecules more accurately and robustly than ever before, in a major potential step for the pharmaceutical industry......»»
Researchers synthesize molecular aggregates for solar energy applications
No molecule stands alone—they need others, at least when it comes to being able to display useful photophysical, electronic, and chemical properties. When individual molecules combine into an aggregate, or a complex of two or more molecules, they b.....»»
Single nucleosomes tracked in live cells during cell division using super-resolution microscopy
Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells. Despite recent advances in cell biology, the mechanism by which DNA condenses during mitosis is still poor.....»»
Chemists succeed in upscaling a common reagent for industrial level applications
The metallic element samarium, when bound with other elements, is an incredibly useful chemical reagent for synthesizing molecules that can lead to new pharmaceuticals. Discovered in a Russian mine in 1879, the element was named after the mineral it.....»»
The secret to sleepy cells" control of inflammatory secretions
Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells. This drowsy condition is known to provide heal.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
AI tackles one of the most difficult challenges in quantum chemistry
New research using neural networks, a form of brain-inspired AI, proposes a solution to the tough challenge of modeling the states of molecules......»»
Novel silica nonwoven fabric scaffold enhances understanding of cell-to-cell interactions
Communication and coordination among different cells are fundamental aspects that regulate many functions in our body. This process, known as paracrine signaling, involves the release of signaling molecules by a cell into its extracellular matrix (EC.....»»
Keychron Q15 Max review: High-quality and quirky mechanical keyboard
The Keychron Q15 Max is a premium keyboard option for those who are on board with ortholinear setups, or want to give it a try.Keychron Q15 Max reviewAn ortholinear keyboard has a non-staggered layout, where keys are aligned in a grid format. They of.....»»
Tissue fluidization during skin repair is crucial for wound healing, study reveals
The ability to repair tissue following injuries is essential for the survival of all animals. Following wounding, the skin is repaired by activating, migrating, and dividing skin stem cells. Defects of wound healing in humans lead to chronic wounds t.....»»