Demonstrating the significance of individual molecules during mechanical stress in cells
The cells in our bodies are continuously exposed to mechanical forces that are either externally applied or generated by the cells themselves. Being able to respond to such mechanical stimuli is an indispensable prerequisite for a large number of bio.....»»
Saturday Citations: Football metaphors in physics; vets treat adorable baby rhino"s broken leg
This week, researchers reported an effective way to protect working dogs from heat stress: training them to dunk their heads in cool water. A new computational technique provided a breakthrough in understanding the so-called "pseudogap" in quantum ph.....»»
New data science tool greatly speeds up molecular analysis of our environment
A research team led by scientists at the University of California, Riverside, has developed a computational workflow for analyzing large data sets in the field of metabolomics, the study of small molecules found within cells, biofluids, tissues, and.....»»
Frostpunk 2 goes wider and more political but keeps the gritty, stressful joy
Sequel has yet again made losing your humanity to survive somehow… fun? Enlarge / Frostpunk 2 has you planning and building districts, rather than individual buildings or roads. You make plans, and a particularly icy god laughs.....»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
How a bacterial pathogen that causes dysentery manipulates molecular activity to assure its survival
Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism. Daniel Capelluto and his research team have discovered the mechanism by which the bacterial pathogen Shigella flexneri, the causative agent of dysen.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
First-of-its kind tool allows scientists to manipulate cells without touching them
When studying the spread of cancer or the behavior of a virus like the one that causes COVID-19, the irony is that working with these harmful pathogens requires gentleness. Especially in the case of COVID, the particles do not survive well when makin.....»»
Redwood Materials signs deal to recycle BMW’s EV batteries in the US
The automaker will use recycled materials from Redwood in its American-made EVs. Enlarge / BMW is moving to cylindrical cells for its sixth-generation EV powertrain, which debuts in the Neue Klasse. And now it has a recycling par.....»»
Antioxidant carbon dot nanozymes alleviate depression in rats by restoring the gut microbiome
Depression is a significant challenge to diagnose and treat. Among the factors influencing depression onset and severity, there is growing evidence for chemical imbalances that generate oxidative stress throughout the body. To address this problem, r.....»»
Silencing in action: How cells "repress" genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of "cryptic" genomic regions, including ancient viral sequences......»»
What Is Sickle Cell Disease?
You have around 35 trillion red blood cells moving around your body at all times. Typically they are rounded and flexible. What happens when they aren’t?.....»»
A key NASA commercial partner faces severe financial challenges
"The business model had to change." Enlarge / Rendering of an individual crew quarter within the Axiom habitat module. (credit: Axiom Space) Axiom Space is facing significant financial headwinds as the company attempts t.....»»
Computational tool can pinpoint causal relationships from complex biological data
Researchers have developed a tool that provides new insights into cause-and-effect relationships between cells and how these change over time......»»
Do bacteria age?
Any organism that lives, grows and reproduces must also age. People often think of aging in the physical sense—gray hair, slowed movements and wrinkles—but aging fundamentally occurs on a molecular level, inside of cells......»»
Team discovers naturally occurring DNA-protein hybrids
Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins—without having to synthesize them one by one, res.....»»
Scientists decipher the energy patterns in our cells
Our cells harness energy for essential functions such as division, wound healing, and our immune response to diseases including cancer. But until now, the mechanics of how that energy affects cell behavior—and how this relates to health outcomes—.....»»
Study sheds light on trade-off between noise and power in nanoscale heat engines
Thanks to nanoscale devices as small as human cells, researchers can create groundbreaking material properties, leading to smaller, faster, and more energy-efficient electronics. However, to fully unlock the potential of nanotechnology, addressing no.....»»
Synthetic mini-motor: Researchers convert chemical energy into rotational energy at the supramolecular level
Researchers at the Technical University of Munich (TUM) have developed an artificial motor at the supramolecular level that can develop impressive power. This wind-up motor is a tiny ribbon made of special molecules. When energy is applied, this ribb.....»»
Optogenetic control reveals collective cell behavior
New research led by the Institute for Bioengineering of Catalonia (IBEC) has studied the migratory movement of groups of cells using light control. The results show that there is no leader cell that directs the collective movement, as previously thou.....»»
Researchers develop new method for delivering RNA and drugs into cells
Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA and potent drugs directly into cells, potentially leading to a more effective treatment of diseases......»»