Crohn"s disease patients have specific IgG antibodies to human bacterial flagellins
Last year, researchers used a mouse model that included immune-reactive T cells from patients with Crohn's disease in a proof-of-principle demonstration that a flagellin-directed immunotherapy might provide similar benefits in patients. Now they have.....»»
Protein study could help researchers develop new antibiotics
A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from.....»»
Improved prime editing system makes gene-sized edits in human cells at therapeutic levels
Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applic.....»»
Astrophysicists calculate the likelihood that Earth was exposed to cold harsh interstellar clouds 2 million years ago
Around two million years ago, Earth was a very different place, with our early human ancestors living alongside saber-toothed tigers, mastodons, and enormous rodents. And, depending on where they were, they may have been cold: Earth had fallen into a.....»»
Scientists have traced the origin of the modern horse to a lineage that emerged 4,200 years ago
The horse transformed human history—and now scientists have a clearer idea of when humans began to transform the horse......»»
Watch a 6-axis motor solve a Rubik’s Cube in less than a third of a second
Getting an AI to distinguish red from orange was a major challenge. Enlarge / So much depends upon a red puzzle cube, pinned by servo motors, inside Mitsubishi. (credit: Mitsubishi) The last time a human set the world re.....»»
Citrus saviors: Scientists discover genetic defense against Huanglongbing disease
The citrus industry faces major challenges from Huanglongbing (HLB) disease, transmitted by the Asian citrus psyllid (ACP). Traditional control methods are often ineffective and environmentally harmful......»»
Unlocking banana disease resistance: Key enzymes identified for phytoalexin synthesis
Bananas are a vital crop globally, but their yields are threatened by various diseases, particularly banana fusarium wilt caused by Fusarium oxysporum. Traditional control methods, including chemical pesticides, pose environmental risks and are not a.....»»
During a year of extremes, carbon dioxide levels surge faster than ever
Carbon dioxide is accumulating in the atmosphere faster than ever—accelerating on a steep rise to levels far above any experienced during human existence, scientists from NOAA and the Scripps Institution of Oceanography at the University of Califor.....»»
Welcome to the age of space skepticism—and a growing revolt against elites
Over the past decade, a new form of skepticism about human activities in space has emerged. It seems to be based exclusively in the western world, and centered around the idea that increasingly ambitious space plans will damage humanity and neglect t.....»»
Study links nanoparticles to altered blood vessel formation in embryos
Human life begins with a single egg cell that grows into a human being with trillions of cells. To ensure that the highly complex development of tissues and organs is as protected as possible, the placental barrier keeps pathogens and foreign substan.....»»
Engineering enzymes to break down microplastics in sewage and wastewater
There are over 5 billion tons of plastic waste accumulated across the planet, much of which are microplastics that may harm human health and pose a long-term threat to agricultural productivity and food security. The gargantuan task of cleaning up th.....»»
iPadOS 18 feature request: Clamshell mode, better Stage Manager, more
We’re just a few days away from WWDC 2024, when Apple will finally unveil the next versions of its operating systems – including iPadOS 18. Although I consider myself a Mac person, I also have an and I like to use it for specific tasks. However,.....»»
Confronting climate change: The genetic makeover of a threatened conifer
Conifers like Cupressus gigantea face significant threats from climate change and human activities, leading to habitat fragmentation and population decline. These challenges reduce genetic diversity and increase inbreeding, potentially accumulating h.....»»
People underestimate the probability of including at least one minority member in a group, research suggests
Human society includes various minority groups. However, it is often difficult to know whether someone is a minority member simply by looking at the person, as minority traits may not be visually apparent (e.g., sexual orientation, color vision defic.....»»
AirTags used by alleged human smuggler may ultimately provide enough evidence for conviction
An alleged member of a Russia-based human smuggling network used at least seven Apple AirTags to stalk his wife. And, they may be his downfall.Apple AirTagIbodullo Muhiddinov Numanovich, a Tajikistan citizen living in the United States, is believed t.....»»
Find out which cyber threats you should be concerned about
This article includes excerpts from various reports that offer statistics and insights into the current cyber threat landscape. Human error still perceived as the Achilles’ heel of cybersecurity Proofpoint | 2024 Voice of the CISO | May 2.....»»
Researchers identify tomato exocarp-specific promoter for genetic enhancements
In a triumph for precision agriculture, researchers have pinpointed a tomato exocarp-specific promoter, unlocking the potential for tailored genetic enhancements. This innovation promises to bolster the fruit's visual appeal, fortify it against envir.....»»
Chasing down a cellular "short circuit" sheds light on how certain diseases begin
A group of researchers at University of California San Diego has identified the cause of a "short-circuit" in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases......»»
Rate of global warming caused by humans is at an all-time high, say scientists
The second annual Indicators of Global Climate Change report, which is led by the University of Leeds, reveals that human-induced warming has risen to 1.19 °C over the past decade (2014-2023)—an increase from the 1.14 °C seen in 2013-2022 (set ou.....»»
Boeing"s Starliner set up for third shot at first human spaceflight
A pair of NASA astronauts will try again on Wednesday morning to take a ride on Boeing's CST-100 Starliner, making its first-ever human spaceflight......»»