Improved prime editing system makes gene-sized edits in human cells at therapeutic levels
Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applic.....»»
Novel catalysts for improved methanol production using carbon dioxide dehydrogenation
Encapsulating copper nanoparticles within hydrophobic porous silicate crystals has been shown by scientists at Tokyo Tech to significantly enhance the catalytic activity of copper-zinc oxide catalysts used in methanol synthesis via CO2 hydrogenation......»»
Human activity: A double-edged sword in the face of drought
Earth and environmental scientists have reported that, as human socio-economic activities increase, greenhouse gas emissions will rise, leading to more frequent extreme weather events such as droughts and floods. However, a research team from Pohang.....»»
Exploring the roots of the Anthropocene
Understanding how tropical land use and deforestation affects the dynamics of the global Earth system and identifying potential tipping points are key to the future of our species on this planet. By exploring the long history of human societies in tr.....»»
Apple Intelligence & iPhone mirroring aren"t coming to EU because of the DMA
Apple isn't releasing Apple Intelligence and other major operating system changes in the EU, because of Digital Markets Act interoperability mandates.European flagsThe biggest changes in Apple's fall operating system updates include the machine learn.....»»
Deep inside iOS 18"s best new features and improvements on the AppleInsider Podcast
It's still only in beta, and there still isn't any sign of Apple Intelligence, but after more than week with iOS 18, there's a lot of good and a little bad to say about Apple's latest iPhone operating system.Some of iOS 18's finest features are major.....»»
Biophysicists decipher functionality of adrenaline-binding receptor
G protein-coupled receptors (GPCRs) are found throughout the human body and are involved in many complex signaling pathways. Despite their importance in many biological processes, the central mechanism of G protein-coupling and the associated signal.....»»
Inspired by nature: Synthetic nightshade molecule effective against leukemia cells
Nightshade plants produce a diverse array of compounds with therapeutic potential. Researchers at CeMM have now identified an artificial variant inspired by the Withanolides group that acts highly specifically against leukemia cells......»»
Scientists solve the puzzle of directional hearing underwater
When underwater, humans cannot determine where a sound comes from. Sound travels about five times faster there than on land. That makes directional hearing, or sound localization, nearly impossible because the human brain determines the origin of a s.....»»
New computational tool helps interpret AI models in genomics
Artificial intelligence continues to squirm its way into many aspects of our lives. But what about biology, the study of life itself? AI can sift through hundreds of thousands of genome data points to identify potential new therapeutic targets. While.....»»
Dietary sucrose determines activity of lithium on gene expression and lifespan in D. melanogaster
The amount of dietary sugars and the administration of lithium both impact the lifespan of the fruit fly Drosophila melanogaster. It is noteworthy that lithium is attributed with insulin-like activity as it stimulates protein kinase B/Akt and suppres.....»»
New tomato, potato family tree shows that fruit color and size evolved together
Fruits of Solanum plants, a group in the nightshade family, are incredibly diverse, ranging from sizable red tomatoes and purple eggplants to the poisonous green berries on potato plants. A new and improved family tree of this group, produced by an i.....»»
Welcome to the drought: Off-lease vehicle pool is about to dry up
Lease turn-ins are a valuable tool for dealers and automakers to control inventory levels. But the 2021 leasing collapse is about to shrink the pool sharply......»»
8 reasons for Apple users to switch to UPDF Editor: AI PDF Assistant
UPDF is an Adobe alternative with an AI twist for reading, annotating, searching, and editing PDFs on Mac. Save big and chat with your PDF today.UPDF Editor: AI PDF AssistantIf you work with PDFs, it can be a pain finding the right tool for the job......»»
Scientists use heart and lung model to calculate potential health threats facing future space tourists in microgravity
Space exploration has always captivated our imagination, offering the promise of discovering new worlds and pushing the boundaries of human capability. As commercial space travel becomes more accessible, individuals with various underlying health con.....»»
Dealership finance offices can still work while CDK is down
The temporary shutdown of the car dealership management system CDK following cyberattacks complicates life for auto retailers' finance and insurance offices. However, it's not insurmountable, according to experts......»»
New iOS 18 API brings AirPods setup experience to third-party accessories
When Apple introduced in 2016, the company also unveiled a new, easy and intuitive way to pair wireless accessories to iPhone and iPad. Rather than having to go to Bluetooth settings and press buttons, the system identifies the accessory nearby and.....»»
Anthropic introduces Claude 3.5 Sonnet, matching GPT-4o on benchmarks
Claude 3.5 Sonnet is a speedy mid-sized entry in a new family of AI models. Enlarge (credit: Anthropic / Benj Edwards) On Thursday, Anthropic announced Claude 3.5 Sonnet, its latest AI language model and the first in a n.....»»
An efficient protein delivery system with spider minor ampullate silk protein nanoparticles
In a study published in the journal MedComm, researchers have developed an efficient protein delivery carrier based on spider silk proteins (spidroins), derived from Araneus ventricosus minor ampullate silk protein (MiSp). The MiSp-based nanoparticle.....»»
Antibiotic-resistance in sub-Saharan Africa "alarming": Studies
Superbug infections are taking a disproportionate toll in sub-Saharan Africa where there is "extremely concerning" levels of multi-resistant bacterial strains among young children, two studies warned Thursday......»»
Sunlight and plastic: A risky combination for bottled water safety
Plastic water bottles are ubiquitous due to their convenience, yet they harbor potential risks. Sunlight exposure can lead these containers to degrade and emit volatile organic compounds (VOCs), which are potentially detrimental to human health. The.....»»