Chemokine receptor CX3CR1 structures uncover mechanism of cholesterol regulation in activation
Chemokine receptors regulate the migration of immune cells and are involved in inflammation, tumor construction and pathogen infection. Chemokines are divided into four subfamilies according to the number and distribution of conserved cysteines at th.....»»
Q&A: Making the case for artisanal and small-scale mining
Artisanal and small-scale mining plays a critical role in supplying the world with minerals vital for decarbonization, but this kind of mining typically lacks regulation and can be socially and environmentally harmful......»»
Scientists uncover hidden source of snow melt: Dark brown carbon
Wildfires leave potent climate heaters behind in their wake, particles that enhance the absorption of sunlight and warm the atmosphere. Dropped on snow like a wool poncho, these aerosols darken and decrease the surface reflectance of snowy places......»»
Drosophila study discovers mechanism that could control longevity, cancer cell production
Researchers at UC Merced have used fruit flies to uncover a cellular process common to many organisms that could dramatically impact the understanding of cancer and aging......»»
Harnessing AI to fight global deforestation
The new European Deforestation Regulation (EUDR) is intended to prevent goods marketed in the EU from contributing to the spread of deforestation. When a wood product is brought into the EU market, for example, there must be documentation of which ty.....»»
Cells use alternative splicing to regulate gene expression, research suggests
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism increases the diversity of proteins that can be generat.....»»
Ancient viral genomes preserved in glaciers reveal climate history—and how viruses adapt to climate change
As humans alter the planet's climate and ecosystems, scientists are looking to Earth's history to help predict what may unfold from climate change. To this end, massive ice structures like glaciers serve as nature's freezers, archiving detailed recor.....»»
Study finds RNA molecule controls butterfly wing coloration
A team of international researchers has uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly wings. In a study published in the Proceedings of the National Academy of Sciences, the team, led by Luca L.....»»
EU investigating if Telegram played down user numbers to avoid regulation
The new probe is separate from the French investigation into the platform. Enlarge (credit: NurPhoto via Getty) Brussels is investigating whether Telegram breached EU digital rules by failing to provide accurate user num.....»»
California legislature passes controversial “kill switch” AI safety bill
Governor will balance worries about "over-regulation" with calls from AI luminaries. Enlarge / California governor Gavin Newsom will likely soon face a decision on whether to sign SB-1047. (credit: Ray Chavez/The Mercury News via.....»»
Novel encoding mechanism unveiled for particle physics
In the development of particle physics, researchers have introduced an innovative particle encoding mechanism that promises to improve how information in particle physics is digitally registered and analyzed. This new method, focusing on the quantum.....»»
Big-name publishers are refusing to let Apple Intelligence train on data
Website owners have a simple mechanism to tell Apple Intelligence not to scrape the site for training purposes, and reportedly major platforms like Facebook and the New York Times are using it.Future expansions to Apple Intelligence may involve more.....»»
Shedding light on the mechanism of yeast DNA repair
DNA damage is a cellular phenomenon that introduces structural abnormalities in double-stranded DNA. External factors, such as radiation or chemical agents, as well as internal factors, such as blocked DNA replication, can generate double-strand brea.....»»
Protein mutant stability can be inferred from AI-predicted structures
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»
Bacterial defense strategy has potential application in genome editing
Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method......»»
New knowledge about cell receptors paves the way for future drugs against intestinal tumors
A new study from Karolinska Institutet published in Nature Communications provides valuable insights into the activation of receptors on the cell surface. The knowledge could lead to new targeted therapies and drugs against intestinal tumors, among o.....»»
Supercomputer simulations reveal the nature of turbulence in black hole accretion disks
Researchers at Tohoku University and Utsunomiya University have made a breakthrough in understanding the complex nature of turbulence in structures called accretion disks surrounding black holes, using state-of-the-art supercomputers to conduct the h.....»»
Researchers map 50,000 of DNA"s mysterious "knots" in the human genome
Researchers have mapped 50,000 of DNA's mysterious "knots" in the human genome. The innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer......»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Addigy launches Apple Intelligence device management controls
Apple device management vendor Addigy has announced the immediate availability of new Apple Intelligence controls. These controls, now live within Addigy’s platform, allow IT administrators and Managed Service Providers to test the activation and d.....»»
OpenAI gets called out for opposing a proposed AI safety bill
"When actual regulation is on the table, he opposes it," the researchers wrote of OpenAI CEO Sam Altman......»»