Chemical trick activates antibiotic directly at the pathogen
Colistin is a last-resort antibiotic that is usually only used for severe infections with resistant bacteria. This is due to its severe kidney-damaging side effects, which occur in about 30% of treated patients. A research team at the Helmholtz Cente.....»»
How thinking about death—mortality salience—drives early Halloween shopping and retail trends
It's becoming as much of a tradition as costumed trick-or-treaters and skeletons crawling across lawns studded with cardboard gravestones: candy corn and jumbo bags of Snickers start popping up on grocery store shelves a few weeks after Independence.....»»
Promising antibiotic candidates discovered in microbes deep in the Arctic Sea
Antibiotics are the linchpin of modern medicine: without them, anyone with open wounds or needing to undergo surgery would be at constant risk of dangerous infections. Yet we continue to face a global antibiotics crisis, as more and more resistant st.....»»
Catalytic process vaporizes plastic bags and bottles, yielding gases to make new, recycled plastics
A new chemical process can essentially vaporize plastics that dominate the waste stream today and turn them into hydrocarbon building blocks for new plastics......»»
Tuberculosis under the sea: A marine sponge microbe provides insights into the bacterium"s evolution
The surprising discovery of a bacterium in a marine sponge from the Great Barrier Reef with striking similarity to Mycobacterium tuberculosis, the pathogen responsible for tuberculosis (TB), could unlock and inform future TB research and treatment st.....»»
Shedding light on the mechanism of yeast DNA repair
DNA damage is a cellular phenomenon that introduces structural abnormalities in double-stranded DNA. External factors, such as radiation or chemical agents, as well as internal factors, such as blocked DNA replication, can generate double-strand brea.....»»
Scientists develop new chemical tool for infection research
Researchers from Würzburg and Berlin present a new molecule for visualizing the sphingomyelin metabolism. This offers prospects for innovative therapeutic approaches in infection research. The work is published in the journal Nature Communications......»»
Chloroplast manipulation: A new strategy in pathogen warfare uncovered
A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»
Researchers develop near-infrared spectroscopy models to analyze corn kernels and biomass
In the agricultural and food industry, determining the chemical composition of raw materials is important for production efficiency, application, and price. Traditional laboratory testing is time-consuming, complicated, and expensive. New research fr.....»»
Apple is replaying its Jony Ive trick to manage Maestri’s departure
Apple yesterday announced Luca Maestri’s upcoming departure from his long-held role as the company’s chief financial officer (CFO), with the relatively unknown Kevan Parekh replacing him. It’s no coincidence that Apple made the announcement.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Study reveals bioactive power of a natural spearmint compound against weeds
A recent study reveals the natural compound (-)-carvone in spearmint as a potent and sustainable alternative to chemical herbicides. This research demonstrates how (-)-carvone targets and degrades microtubules in weeds, inducing cell death and inhibi.....»»
Researchers synthesize molecular aggregates for solar energy applications
No molecule stands alone—they need others, at least when it comes to being able to display useful photophysical, electronic, and chemical properties. When individual molecules combine into an aggregate, or a complex of two or more molecules, they b.....»»
Chemists succeed in upscaling a common reagent for industrial level applications
The metallic element samarium, when bound with other elements, is an incredibly useful chemical reagent for synthesizing molecules that can lead to new pharmaceuticals. Discovered in a Russian mine in 1879, the element was named after the mineral it.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
Novel technique allows malicious apps to escape iOS and Android guardrails
Web-based apps escape iOS "Walled Garden" and Android side-loading protections. Enlarge (credit: Getty Images) Phishers are using a novel technique to trick iOS and Android users into installing malicious apps that bypas.....»»
Scientists help turn whisky waste into valuable commodity
A new method to extract valuable bio-based chemicals from whisky distillery waste streams could transform manufacturing and be worth up to £90 million in global chemical manufacturing markets......»»
First visualization of valence electrons reveals fundamental nature of chemical bonding
The distribution of outermost shell electrons, known as valence electrons, of organic molecules was experimentally observed for the first time by a team led by Nagoya University in Japan. As the interactions between atoms are governed by the valence.....»»
Study finds "DNA scavengers" can stop some antibiotic resistance from spreading
For nearly a century, scientists have waged war on antibiotic-resistant microbes. Michigan State University researchers say they've found a new way to prevent it—by unleashing "DNA scavengers" in wastewater treatment plants......»»
AI accelerates discovery of next-gen polymers
Nylon, Teflon, Kevlar. These are just a few familiar polymers—large-molecule chemical compounds—that have changed the world. From Teflon-coated frying pans to 3D printing, polymers are vital to creating the systems that make the world function be.....»»
A European lander could return an ice core for a fraction of the cost of Europa Clipper
Cost is a major driving factor in the development of space exploration missions. Any new technology or trick that could lower the cost of a mission makes it much more appealing for mission planners. Therefore, much of NASA's research goes into those.....»»