Biosynthesis pathway of a new DNA nucleobase elucidated
DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. This exception, the only.....»»
New signaling pathway decoded in the decomposition of damaged lysosomes
Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can trigger inflammation a.....»»
Researchers reveal evolutionary path of important proteins
New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression......»»
Researchers discover new microRNA-regulated pathway to boost iPS cell-derived platelet production
A team of researchers led by Professor Koji Eto (Department of Clinical Application) recently discovered the importance of a microRNA-based regulatory mechanism for enhancing the quality and quantity of platelets generated by iPS cell-derived megakar.....»»
Core-shell structural units show outstanding toughening effect for ceramics
Toughening has always been an important research direction of structure ceramics. The addition of secondary phases to the ceramic matrix to prepare composite ceramics is an effective toughening pathway in the field of structure ceramics......»»
Research team establishes synthetic dimension dynamics to manipulate light
In the realm of physics, synthetic dimensions (SDs) have emerged as one of the frontiers of active research, offering a pathway to explore phenomena in higher-dimensional spaces, beyond our conventional 3D geometrical space. The concept has garnered.....»»
Electronic perturbation-promoted interfacial pathway for facile C–H dissociation
Pt-based catalysts have been extensively employed in catalytic propane dehydrogenation (PDH) processes, playing a crucial role in propylene production. However, monometallic Pt catalysts often exhibit inferior propylene selectivity due to the hydroge.....»»
Pesticide-free as a new pathway for agriculture
A new approach is gaining momentum in European agriculture: a "third way" that lies between conventional production and organic farming systems. Here farmers must forego synthetic pesticides only—which is simpler to implement than a switch to organ.....»»
Scientists find that micronuclei are not the primary trigger of the cGAS/STING pathway
Cells possess an innate immune system that defends against invasive pathogens such as bacteria and viruses. Previous studies have mapped out the cytoplasmic cGAS-STING pathway in the cytoplasm, known for responding to foreign nucleic acids, such as d.....»»
How having self-control leads to power
Out-of-control behavior by CEOs and other powerful people constantly makes headlines—so much so that some might consider impulsivity a pathway to power. New research from the UC San Diego Rady School of Management and Texas A&M University finds tha.....»»
Exploring the landscape of shadow education
The diverse forms of private tutoring range from one-to-one sessions to large lecture halls with video screens. Parents and students seek this supplement to gain a competitive edge in countries where academic achievement is seen as a pathway to futur.....»»
Alternative splicing and transcription factor interplay in blood orange anthocyanin biosynthesis
The blood orange, renowned for its vibrant color due to anthocyanins, is a focus of increasing demand in the nutraceutical industry, with 'Tarocco' [C. sinensis (L.) Osbeck] being the most widespread variety. Current research sheds light on the genet.....»»
The Future of Mobile App Development and Why Flutter is Leading the Way
Mobile application development has experienced a radical pathway, traversing an evolutionary course that calibrates with the pacing of technological advancements and the changing perception of users. The evolution from the simple utilities of the yes.....»»
Unlocking the secrets of geraniol: A key to enhanced disease resistance in tea plants
Geraniol contributes to the floral scent of tea (Camellia sinensis) and is abundant in tea plants, yet its biosynthesis and role in stress responses remain unclear......»»
Hot stuff: A new thermal pathway for a high explosive
TATB (1,3,5-triamino-2,4,6-trinitrobenzene) is an important explosive compound because of its extensive use in munitions and worldwide weapons systems. Despite its importance, researchers have been trying to understand its response to temperature ext.....»»
Scientists discover why ripe fruit is more susceptible to necrotrophic pathogens than unripe fruit
In a recent study published in Molecular Plant, researchers have elucidated the mechanism underlying the increased susceptibility to necrotrophs during fruit ripening and have developed a rapid strategy to improve tomato fruit resistance to necrotrop.....»»
Unlocking the color code: The role of VvBBX44 and VvMYBA1 in regulating grape anthocyanin biosynthesis
Anthocyanins significantly influence grape quality and color, with transcription factors HY5 and MYBA1 playing pivotal roles in their biosynthesis. Recent findings show that VvBBX44, a B-box protein, inhibits anthocyanin production in grapes by suppr.....»»
RNA-sequencing analysis reveals key genes behind eggplant peel variation
Anthocyanins give fruits and vegetables their red, purple, and blue colors, offering health benefits. Their biosynthesis involves specific enzymes and is regulated by the MBW complex of transcription factors. Research has linked color variations in p.....»»
CRISPR/Cas9-mediated targeted mutagenesis of inulin biosynthesis in rubber dandelion
Researchers have leveraged the power of the CRISPR/Cas9 genome editing system to enhance natural rubber production in rubber dandelion (Taraxacum kok-saghyz). The CRISPR system's efficiency and precision offer a promising avenue to address challenges.....»»
Important molecular pathway for control of aging discovered
One of the ways cells in different kinds of tissue communicate is by exchanging RNA molecules. In experiments with roundworms of the species Caenorhabditis elegans, researchers at the State University of Campinas (UNICAMP) in Brazil found that when t.....»»
An evolutionarily conserved pathway that achieves a peaceful co-existence with genomic parasites
Transposable elements are mobile genetic elements that can relocate within the genome and disrupt the normal function of genes, but are at the same time a source of evolutionary diversity. The lab of Tugce Aktas at the Max Planck Institute for Molecu.....»»