Biosynthesis pathway of a new DNA nucleobase elucidated
DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. This exception, the only.....»»
New research opens avenues for more efficient and stable blue OLED displays
New research from scientists at Durham University reveals an unexpected pathway toward brighter, more efficient, and more stable blue organic light-emitting diodes (OLEDs)......»»
Unveiling biosynthesis of hyperoside: A pathway to sustainable production in Hypericum monogynum
Hyperoside, a beneficial flavonoid galactoside found in both medicinal and edible plants, plays a critical role in plant growth, self-defense, and breeding, as well as in human health through its numerous pharmacological properties. However, the bios.....»»
Deciphering the ethylene biosynthesis puzzle in banana fruit ripening
Ethylene, a key phytohormone, plays a vital role in the ripening of climacteric fruits like bananas, with its biosynthesis being a focal point of agricultural research due to its impact on fruit quality and shelf life. Transcription factors(TFs), suc.....»»
Grape white rot resistance and the role of VvWRKY5 in enhancing pathogen defense through the jasmonic acid pathway
Grape white rot, caused by Coniella diplodiella (Speg.) Sacc. (Cd), significantly impacts grape production and quality, highlighting the need for effective disease management strategies beyond fungicide use due to concerns over food safety and enviro.....»»
Study reveals mechanisms behind how growing cells maintain their mojo by scaling up biosynthesis
Similar to the way expanding companies increase their work forces, cells must boost their production of internal biomolecules when they grow in size in order to stay healthy. In the 1970s, biologists showed that this scaled-up biosynthesis hinges on.....»»
Chromatin modifier-centered pathway points to higher crop yield
A team led by Prof. Song Xianjun from the Institute of Botany of the Chinese Academy of Sciences, while researching a ternary protein complex in rice nuclei that affects grain size, has shown that the transcription factor bZIP23—a protein that regu.....»»
Axiom and SpaceX are disrupting Europe’s traditional pathway to space
The program sees more countries get access to space, but the details are murky. Enlarge / A Falcon 9 rocket launches the Axiom-2 mission on May 21, 2023. (credit: SpaceX) The European Space Agency’s (ESA) has a deal wi.....»»
Breakthrough in nitrile activation is promising pathway for anticancer precursor synthesis
A research team, affiliated with UNIST has unveiled a novel method to produce a selective anticancer precursor substance that targets and eliminates cancer cells. This groundbreaking method, previously existing only in theory, has now been experiment.....»»
Artificial design and biosynthesis of a single-domain catenated dihydrofolate reductase
This study was led by Prof. Wen-Bin Zhang (College of Chemistry and Molecular Engineering, Peking University & Beijing Academy of Artificial Intelligence) and Dr. Jing Fang (College of Chemistry and Molecular Engineering, Peking University). A single.....»»
Novel molecular ionization dissociation pathway induced by Interatomic Coulombic Decay
A research group led by Prof. Ma Xinwen at the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS) has observed a novel molecular ionization dissociation pathway triggered by Interatomic Coulombic Decay (ICD). The study, publis.....»»
Fifth national climate assessment emphasizes mitigation
The latest National Climate Assessment highlights historic emissions reductions and outlines new guidance for achieving a net-zero emissions pathway......»»
New understanding of ancient genetic parasite may spur medical breakthroughs
A multidisciplinary study published in Nature has elucidated the structure of the machinery responsible for writing much of our "dark genome"—the 98% of our DNA that has largely unknown biological function. These results may spur entirely novel tre.....»»
Scientists identify biosynthetic pathway of chemotherapeutic derived from yew trees
Researchers from the Max Planck Institute of Molecular Plant Physiology have unraveled the biosynthetic pathway of paclitaxel in yew plants, a chemotherapeutic for cancer treatment. This discovery might facilitate the production of this very complex.....»»
Study presents new pathway for electrochemically controlling ion selectivity
A new study by researchers at the University of Illinois Urbana-Champaign advances fundamental knowledge about the role of solvation in ion binding and presents a new pathway for electrochemically controlling ion selectivity. The study was published.....»»
Researchers elucidate how IGF2"s secretory pathway mediates muscle stem cell differentiation
A research team led by the Hong Kong University of Science and Technology (HKUST) recently revealed how TMED10, a type of transmembrane protein, regulates muscle stem cell differentiation through mediating the secretion of insulin-like growth factor.....»»
MicroRNA holds clues to why some mammals are cancer-prone
Researchers at the College of Veterinary Medicine (CVM) have identified an important pathway that reveals why some mammals, like humans, dogs, and cats, regularly develop mammary cancer while others, such as horses, pigs, and cows, rarely do......»»
Scientists discover a new stress response pathway for repairing RNA-protein crosslinks caused by toxic aldehydes
The research team of Professor Petra Beli and their collaborators have discovered that aldehydes, a type of toxic chemical produced by the body after drinking alcohol, damage cells by creating chemical crosslinks between RNA and proteins, thereby int.....»»
Yeast engineering leads to new frontiers in jasmonate biosynthesis
A research team led by Prof. Luo Xiaozhou from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and Prof. Jay D. Keasling from the University of California, Berkeley, has developed an engineered yeast to p.....»»
The Wnt signaling pathway: The foundation of cell growth, development, and potential therapeutics
The Wnt signaling pathway, a system present in living organisms, plays a pivotal role in cell growth, differentiation, and migration. It has a long history dating back to 1982, when the first Wnt gene, essential for cellular growth, was discovered. T.....»»
A high-quality Bougainvillea genome helps to explore evolutionary history of a pigment biosynthetic pathway
Bougainvillea, a widely appreciated ornamental shrub, originates from South America and stands out due to its vibrant bract colors, which are believed to result from betalain accumulation. Although Bougainvillea has important ornamental and prophylac.....»»