Biochemists uncover a new enzyme subclass in antimicrobial lanthipeptide biosynthesis
Biochemists from the National University of Singapore (NUS) have discovered a new subclass of trifunctional enzymes in gram-positive bacteria, which play a critical role in the biosynthesis of an antimicrobial lanthipeptide......»»
Salt Security provides improved API protection with Google Cloud
Salt Security announced its integration with Google Cloud‘s Apigee API Management platform. With this technical collaboration, customers can discover all of their APIs, including shadow and deprecated APIs, apply posture rules, uncover areas of.....»»
Ancient DNA helps uncover the Iberian lynx"s potential secret weapon against extinction
Many large mammals have lost genetic diversity, often thanks to the actions of people shrinking their populations. The implications can be severe because without genetic diversity, a population does not have a "genetic database" to fall back on to ad.....»»
Neutron experiments settle 40-year debate on enzyme for drug design
In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers......»»
Researchers uncover key insights into cholesterol"s structure in cell membranes
A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization. Th.....»»
AI tools help uncover enzyme mechanisms for lasso peptides
Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tes.....»»
Genome sequence analysis identifies new driver of antimicrobial resistance
Antibiotics are a lifesaving tool. Yet, due to their chronic overuse, microbes are evolving and developing immunity against them. As a result, once-effective medications can no longer stave off infections, complicating treatment and increasing mortal.....»»
Exploring the interplay between phosphate signaling and jasmonate pathways in tea plants
Catechins, the key active components in tea, are known for their protective effects against conditions like diabetes, cancer, and cardiovascular diseases. However, their biosynthesis is highly sensitive to environmental factors, particularly phosphat.....»»
New testing system uses Janus particles to rapidly and accurately detect COVID-19
The importance of testing for diseases was thrust into the limelight during the COVID-19 pandemic. Many of us have undergone a PCR (Polymerase Chain Reaction) or ELISA (Enzyme-Linked Immunosorbent Assay) test within the past four years......»»
Bioengineers create new substrate to study wood-decomposing enzyme
Researchers want to transform the natural and abundant resource wood into useful materials, and central to that is a molecular machine found in fungi that decomposes the complex raw material into its basic components......»»
Enzyme-inspired catalyst puts chemicals in right position to make ethers
Taking inspiration from enzymes, chemists at the University of Illinois Urbana-Champaign developed a catalyst to simplify the synthesis of ethers, key functional components of many drugs, foods, personal care items and other consumer goods. The catal.....»»
Dru Investigate simplifies cyber investigations and helps users uncover data threats
Druva launched Dru Investigate, a gen AI-powered tool that guides data security investigations using a natural language interface. With Dru Investigate, users across IT, security, legal, and privacy teams can swiftly identify and mitigate data risks,.....»»
New findings in a decade-long study of enzyme catalysis
Synthetic chemistry provides an essential material basis for our clothing, food, housing, transportation, and medicine and is an important driving force for economic development. However, traditional chemical synthesis has bottleneck problems such as.....»»
Study reviews ginsenoside biosynthesis and regulation in Panax notoginseng
Panax notoginseng, a perennial herb central to traditional Chinese medicine, is celebrated for its health benefits, such as promoting blood circulation and reducing inflammation. Its key components, ginsenosides, are associated with various pharmacol.....»»
The olive tree"s blueprint: Key insights into high-quality oil production
A pivotal study has decoded the genetic basis of olive oil production, revealing a key regulatory mechanism that shapes oil biosynthesis. By mapping the olive tree's genome and metabolic pathways, researchers have identified how MYC2, a critical tran.....»»
Newly discovered antimicrobial could prevent or treat cholera
More than a million people each year die from infections by pathogens that are resistant to antimicrobials, and the problem is growing. Meanwhile, the discovery of new antimicrobials that can help stem the tide has not kept pace......»»
Researchers uncover new infection-fighting molecules through "molecular de-extinction"
A new study led by Cesar de la Fuente, Ph.D., Presidential Assistant Professor of Psychiatry, Microbiology, Chemistry, Chemical and Biomolecular Engineering, and Bioengineering at the University of Pennsylvania, has uncovered sequences for infection-.....»»
Researchers identify new tools for anti-Acinetobacter drug development and AMR preparedness
University of Liverpool researchers have engineered a library of strains that can be used to develop new antibacterial compounds to help address antimicrobial resistance (AMR) in Acinetobacter baumannii bacteria......»»
Social media interviews uncover New Yorkers" frustrations with high energy costs and reliability
Researchers at Columbia University Mailman School of Public Health are using a novel interview method to assess New Yorkers' perceptions and feelings related to their difficulties paying for and controlling heating and cooling in their homes. Inspire.....»»
Scientists uncover hidden source of snow melt: Dark brown carbon
Wildfires leave potent climate heaters behind in their wake, particles that enhance the absorption of sunlight and warm the atmosphere. Dropped on snow like a wool poncho, these aerosols darken and decrease the surface reflectance of snowy places......»»
Drosophila study discovers mechanism that could control longevity, cancer cell production
Researchers at UC Merced have used fruit flies to uncover a cellular process common to many organisms that could dramatically impact the understanding of cancer and aging......»»