Battling drug resistant bacteria with bacteriophages
The overuse of antibiotics over extended periods of time has led to the emergence of multidrug-resistant (MDR) bacteria in recent years. This poses a significant threat to public health, with more than 1.2 million deaths caused due to MDR bacteria. M.....»»
Better together: Gut microbiome communities found to have enhanced resilience to drugs
Many human medications can directly inhibit the growth and alter the function of the bacteria that constitute our gut microbiome. EMBL Heidelberg researchers have now discovered that this effect is reduced when bacteria form communities......»»
Graphene spike mat uses ordinary fridge magnet tech to fight antibiotic resistance
With strong bactericidal properties, graphene has the potential to become a game changer in the fight against antibiotic-resistant bacteria. So far there have been no efficient ways to control these properties—and thus no way to make use of graphen.....»»
Gun violence in Philadelphia plummeted in 2024—researchers aren"t sure why, but here are 3 factors at play
Philadelphia experienced a surge in shootings and homicides during the COVID-19 years that disproportionately affected young Black and Latino men in economically disadvantaged neighborhoods with drug markets......»»
Can our stockpiles of Tamiflu protect against a bird flu pandemic?
Governments are banking on this old drug in the event of an H5N1 outbreak. Enlarge / A box and a tablet of Roche Pharmaceuticals' Tamiflu pills for influenza. (credit: Nikos Pekiaridis/NurPhoto via Getty Images) Since re.....»»
Chemists discover new ways in which single-celled organisms organize their DNA
It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden Ph.D. candidate Samuel Schwab has found that the histones in these organisms are much more diverse.....»»
Experts discover the deadly genetics of cholera, which could be key to its prevention
Experts have used a cutting-edge computational approach to discover the genetic factors that make the bacteria behind cholera so dangerous—which could be key to preventing this deadly disease......»»
Cocaine found in mummified brains reveal that New World drug came to Italy 200 years earlier than thought
Cocaine found in mummified brains reveal that New World drug came to Italy 200 years earlier than thought.....»»
AI tools help uncover enzyme mechanisms for lasso peptides
Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tes.....»»
AI for drug discovery: DrugSynthMC to make finding new medication more efficient
Scientists have devised a free AI algorithm that they believe will make finding new medicines far more efficient......»»
How a bacterial pathogen that causes dysentery manipulates molecular activity to assure its survival
Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism. Daniel Capelluto and his research team have discovered the mechanism by which the bacterial pathogen Shigella flexneri, the causative agent of dysen.....»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»
A drug made by a Florida company has been recalled for a possibly lethal contamination
A drug made by a Florida company has been recalled for a possibly lethal contamination.....»»
Was Thalidomide Safe? Frances Oldham Kelsey Was Not Convinced
In the U.S. in the early 1960s the distributor of a thalidomide drug was impatient to get it on the market. But FDA medical examiner Frances Oldham Kelsey wanted more information to prove its safety.....»»
Obesity-Drug Pioneers Win Prestigious Lasker Award for Medical Science
Three scientists are honored for developing a class of blockbuster weight-loss drugs. Is a Nobel prize on the way?.....»»
Homeopathic company refuses to recall life-threatening nasal spray, FDA says
Consumers should stop using SnoreStop, FDA says. Enlarge (credit: Getty | Florian Gaertner) The maker of a homeopathic nasal spray with a history of contamination is refusing to recall its product after the Food and Drug.....»»
Plant pathogen battle: A tomato protein"s dual role in defense and susceptibility
Tomatoes, a staple crop worldwide, are increasingly threatened by biotic stressors such as viruses, fungi, and bacteria, with the effects worsening under climate change. These challenges lead to reduced yields and compromised nutritional quality, hig.....»»
In morning raids in Erie, FBI makes arrests on drug, weapon charges. 24 defendants named
In morning raids in Erie, FBI makes arrests on drug, weapon charges. 24 defendants named.....»»
Harmless strain of E. coli bacteria may be able to prevent urinary tract infections
Researchers from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) and the College of Engineering are collaborating on a project that uses harmless strains of E. coli bacteria to disrupt the bacteria responsible for urinary.....»»
Scientists identify 18 bacterial strains to treat antibiotic-resistant gut infections
Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time. Gram-negative bacteria such as Enteroba.....»»
The Devil in the Details, Chapter One: The Doctor Who Said No to Thalidomide
Starting with her rejection of an FDA application for thalidomide in 1960, physician and pharmacist Frances Oldham Kelsey took a stand against the now infamous drug.....»»