Antifungal activity of a maleimide derivative: Disruption of cell membranes and interference with iron ion homoeostasis
A small molecule library consisting of 40 compounds, specifically N-substituted maleimide and its derivatives, were initially screened in a study published in the journal Mycology, which was led by Prof. Ying Li (Xuzhou Medical University), Prof. Zuo.....»»
Future space telescopes could be made from thin membranes, unrolled in space to enormous size
Space-based telescopes are remarkable. Their view isn't obscured by the weather in our atmosphere, and so they can capture incredibly detailed images of the heavens. Unfortunately, they are quite limited in mirror size......»»
UK finance regulator wants businesses to better prepare for IT meltdowns
An over-reliance on unregulated third parties has led to operational disruption.....»»
Biochemists create protocells to explore how lipids may have led to first cell membranes
A team of biochemists at the University of California, San Diego, working with a group of biochemical engineers from the University of California, Los Angeles, has found that the development of short lipids might have led to the development of the fi.....»»
Asia"s factory activity stagnates, taking shine off rebound in China
Asia"s factory activity stagnates, taking shine off rebound in China.....»»
Google Maps adding weather disruption reporting & more detailed driving map
In addition to Gemini for search, summaries, and Q&A, Google Maps for Android and iOS are getting updates to improve the entire driving experience “from start to finish.” more….....»»
Compact in-incubator imaging device allows real-time remote monitoring of cell growth
Unlike most cells in the human body, stem cells have the unique ability to divide indefinitely. This property makes them especially appealing to scientists exploring ways to extend human lifespans or develop new methods for repairing damaged tissues......»»
Antithrombin study proposes new mechanism of action for the plasma protein"s functional role
Antithrombin, a plasma protein, has been reported to control thrombin activity by directly binding to thrombin, as well as to have an anti-inflammatory effect. However, the actual molecular mechanism of the anti-inflammatory effect of antithrombin wa.....»»
Innovative model offers new way for astronomers to analyze powerful space explosions
Astrophysical explosions are, to give a few examples, driven by the collapse of the iron core of a massive star (known as a core-collapse supernova), the consumption of spaghettified stellar remains by a massive black hole (known as a tidal disruptio.....»»
US charges suspected Redline infostealer developer, admin
The identity of a suspected developer and administrator of the Redline malware-as-a-service operation has been revealed: Russian national Maxim Rudometov. Infrastructure takedown As promised on Monday when they announced the disruption of the Redline.....»»
Team observes how iron atoms alter grain boundary structures in titanium
Using state-of-the-art microscopy and simulation techniques, an international research team has systematically observed how iron atoms alter the structure of grain boundaries in titanium. Their findings were published in the journal Science on Octobe.....»»
Scientists provide direct evidence of breakdown of spin statistics in ion-atom charge exchange collisions
Since the first X-ray image of a comet was reported using an X-ray telescope in 1996, the investigation of charge exchange in collisions between highly charged ions and atoms or molecules has emerged as a hot research topic......»»
Glycans can regulate their own biosynthesis by modifying enzyme activity
Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics. Glycans can be incredibly complex and branched in structure, contributing to the stability of the extracellular domain of cells and.....»»
Scientists create a molecular switch that can control cell division on demand outside of a living system
A living cell is a bustling metropolis, with countless molecules and proteins navigating crowded spaces in every direction. Cell division is a grand event which completely transforms the landscape. The cell starts behaving like the host of an interna.....»»
Discovery of critical iron-transport protein in malaria parasites could lead to faster-acting medications
Malaria kills over 600,000 people a year, and as the climate warms, the potential range of the disease is growing. While some drugs can effectively prevent and treat malaria, resistance to those drugs is also on the rise......»»
A good cyber leader prioritizes the greater good
In the war against malicious cyber activity, it’s time for security vendors to step in – and it’s not how you might think. CISA Director Jen Easterly put it right at this year’s Black Hat conference: “We got ourselves into this; we have to.....»»
Ion engines could take us to the solar gravitational lens in less than 13 years, suggests paper
Sending an object to another star is still the stuff of science fiction. But some concrete missions could get us at least part way there. These "interstellar precursor missions" include a trip to the solar gravitational lens point at 550 AU from the.....»»
Synthesis method improves catalytic activity by controlling the surface structure of metal particles
Fine-tuning the reactions that produce hydrogen (H2) for use as a clean fuel is an important endeavor to fight against climate change. Researchers at Tohoku University and the Tokyo University of Science have succeeded in improving the catalytic acti.....»»
Research on how gut bacteria breaks down dietary fiber could lead to helpful new probiotics
There are trillions of bacteria in the human gut microbiome. When we eat fruits and vegetables, some of these bacteria break down the dietary fiber and provide us with metabolites, small molecules our body can use for energy or cell repair......»»
Natural compound found in flowers blocks activity of an enzyme involved in multiple sclerosis and cancer
Scientists have identified a natural compound that halts the process involved in the progression of certain forms of cancer and demyelinating conditions—those that damage the sheath, known as myelin, that surrounds neurons—such as multiple sclero.....»»
Microbes feed on iron: New study reveals how they do it
Pipelines, sprinklers, and other infrastructure in oxygen-free environments are vulnerable to microbially induced corrosion (MIC)—a process where microorganisms degrade iron-based structures, potentially leading to costly damages or even collapses......»»