Antibodies and SARS-CoV-2 infections: Tthe more the better
Oxford University Hospital tracked infections in 12,500 of its healthcare workers. Enlarge / Oxford University is associated with the hospital that ran this study, as well as a vaccine that is currently undergoing clinical trials. (credit: Gallo.....»»
Researchers resolve old mystery of how phages disarm pathogenic bacteria
Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise. In response, scientists at Texas A&M AgriLife Research are elucidating the ways that bacteria-infecti.....»»
A new coating method in mRNA engineering points the way to advanced therapies
Medicine can help to treat certain illnesses; for example, antibiotics can help overcome infections, but a new, promising field of medicine involves providing our body with the "blueprint" for how to defeat illnesses on its own......»»
Scientists report that buffer and pH strongly affect the phase separation of SARS-CoV-2 N protein
In a new paper published in Molecular Biology of the Cell, the Allain lab (IBC) reported that the phase separation of the SARS-CoV-2 N protein strongly depends on the chosen buffer and pH. For example, the protonation of a single histidine side chain.....»»
Attack and defense in the microverse: How small RNA molecules regulate viral infections of bacteria
Viruses need hosts. Whether it's measles, the flu or coronavirus, viral pathogens cannot multiply or infect other organisms without the assistance of their hosts' cellular infrastructure. However, humans are not the only ones affected by viruses: ani.....»»
Unlocking the secrets of disease resistance in chrysanthemums: A holistic approach to combating black spot disease
Chrysanthemum, celebrated for its ornamental, medicinal, and beverage value, faces significant threats from bacterial and fungal infections, particularly black spot disease caused by Alternaria alternate, which leads to severe economic losses. Curren.....»»
Must mRNA be cloaked in a lipid coat to serve as a vaccine?
The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus causing COVID-19, in mic.....»»
New antibiotic class effective against multidrug-resistant bacteria discovered
Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic class is described in an article i.....»»
Biochemists discover first new antibacterial class in decades
Vanderbilt biochemists are part of a team taking a stride toward the development of antibacterials to treat uncomplicated urinary tract infections, a pervasive bacterial infection that affects 50%–60% of women in their lifetime......»»
Sniffing out bacteria: Team develops a novel approach for rapid bacterial species identification
Do you ever wonder how researchers identify bacterial infections? Traditionally, they collect samples from the infected site, grow the bacteria in a lab, and analyze them using a method called MALDI-ToF-MS. Although accurate, this method is time-cons.....»»
A closer look into cryptococcal fungal infections in pets
Allowing pets to roam outdoors can seem like harmless fun, providing them with exercise, mental stimulation, and a chance to explore......»»
Antibodies against anything? AI tool adapted to make them
Right now, making antibodies means immunizing animals. But that may change. Enlarge Antibodies are incredibly useful. Lots of recently developed drugs rely on antibodies that bind to and block the activity of specific p.....»»
Nanoparticles target multiple COVID variants through the twist in the spike protein
Teardrop-shaped particles designed to inactivate multiple strains of the SARS-CoV-2 virus could one day complement existing treatments for COVID-19, according to a new study led by researchers at the University of Michigan and Jiangnan University in.....»»
FDA approves first drug to treat yeast ear infections in dogs
The U.S. Food and Drug Administration has approved the first drug to treat yeast ear infections in dogs......»»
Using a non-destructive, light diffraction fingerprint technique to detect viral infections in cells
A combined team of engineers from Jiangsu University and Harvard University used a non-destructive, light diffraction fingerprint technique to detect viral infections in cells. Their paper is published in the journal Science Advances......»»
Nanozyme-enabled nanodecoys: A new strategy for fighting urinary tract infections
Urinary tract infections (UTIs), affecting millions worldwide, are predominantly caused by uropathogenic Escherichia coli (UPEC). These infections are characterized by bacterial adhesion and colonization in the urinary tract, evading host immune resp.....»»
New bioengineered protein design shows promise in fighting COVID-19
In the wake of the COVID-19 pandemic, scientists have been racing to develop effective treatments and preventatives against the virus. A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus re.....»»
New starting point discovered in the fight against P. aeruginosa
Pseudomonas aeruginosa is an important opportunistic pathogen responsible for life-threatening infections that are associated with high rates of morbidity and mortality. Researchers from TWINCORE, the Center for Experimental and Clinical Infection Re.....»»
Sugar-coated gold nanoparticles can quickly eliminate bacterial infections, no antibiotics required
If left to their own devices, bacteria on our teeth or wounded skin can encase themselves in a slimy scaffolding, turning into what is called biofilm. These bacteria wreak havoc on our tissue and, being shielded from antibiotic medication by the slim.....»»
Rogue enzymes cause numerous diseases, but a new method could help design drugs to treat them
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs......»»
Possible "Trojan Horse" found for treating stubborn bacterial infections
Bacteria can be tricked into sending death signals to stop the growth of their slimy, protective homes that lead to deadly infections, a new study demonstrates......»»