Antibodies and SARS-CoV-2 infections: Tthe more the better
Oxford University Hospital tracked infections in 12,500 of its healthcare workers. Enlarge / Oxford University is associated with the hospital that ran this study, as well as a vaccine that is currently undergoing clinical trials. (credit: Gallo.....»»
Researchers study first stem cells from a bat species known to harbor SARS-CoV-2
Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses. This research opens the door to st.....»»
Study identifies novel host protease determinants for SARS-CoV-2 infection
Researchers from Department of Microbiology, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified novel host protease determinants that facilitate the infection of SARS-CoV-2, including the omicro.....»»
Method for quantifying the spread of bacterial resistance to antibiotics developed
The discovery of antibiotics is one of the greatest advances in medicine, as it has enabled the effective treatment of infections caused by pathogenic bacteria. However, these compounds have been losing effectiveness due to the spread of genes that c.....»»
Weaponizing part of the SARS-CoV-2 spike protein against itself to prevent infection
The virus that causes COVID-19, called SARS-CoV-2, uses its spike protein in order to stick to and infect our cells. The final step for the virus to enter our cells is for part of its spike protein to act like a twist tie, forcing the host cell's out.....»»
What an international team charting the threat of killer fungi found
Fungal infections have received a frenzy of attention thanks to the popularity of HBO's "The Last of Us." The show depicts a fungal pandemic caused by the real-life zombie-ant fungus, Ophiocordyceps unilateralis. It imagines the outcome of society's.....»»
Risk of diabetes rises 58% after COVID, even amid omicron, study finds
This is the latest study finding COVID infections can spur the development of diabetes. Enlarge / A woman with diabetes pricks her finger to take a blood sample to measure the glycemia in Paris on March 24, 2020. (credit: Getty |.....»»
Addition of antioxidants to cell cultures can enhance the production of monoclonal antibodies
Researchers at the Department of Chemical Engineering, Indian Institute of Technology, India, have investigated the effects of oxidative stress on the production of monoclonal antibodies (mAbs), and how antioxidants can alleviate this stress to impro.....»»
Detecting rapidly mutating bacteria and viruses with AutoPLP
As we now know from our experience with the COVID-19 pandemic, the microbes responsible for some infections can rapidly mutate into variants that evade detection and treatment......»»
Study reveals how drug resistant bacteria secrete toxins, suggesting targets to reduce virulence
Antimicrobial resistance represents one of the top 10 global public health threats according to the World Health Organization, and scientists have been scrambling to find new tools to cure the most deadly drug-resistant infections......»»
A Crucial Group of Covid Drugs Has Stopped Working
A key tool in the early pandemic response, monoclonal antibodies are now ineffective against new variants. Immunocompromised patients are especially at risk......»»
Identification of novel mutations associated with bedaquiline resistance in Mycobacterium marinum
As infections caused by nontuberculous mycobacteria (NTM) are rapidly increasing globally, a need exists for developing novel antibiotics and discovering the mechanism of resistance. New research reported in Zoonoses is aimed at understanding the mec.....»»
Researchers find deer carry SARS-CoV-2 variants that are extinct in humans
Cornell University researchers have found that white-tailed deer—the most abundant large mammal in North America—are harboring SARS-CoV-2 variants that were once widely circulated, but no longer found in humans......»»
New study into tuberculosis membrane molecules could aid drug delivery
A new method to aid in the development of antibiotics for tuberculosis (TB) infections has been devised......»»
Artificial intelligence aids discovery of super tight-binding antibodies
Scientists at University of California San Diego School of Medicine have developed an artificial intelligence (AI)-based strategy for discovering high-affinity antibody drugs......»»
Warmer climate may drive fungi to be more dangerous to our health
The world is filled with tiny creatures that find us delicious. Bacteria and viruses are the obvious bad guys, drivers of deadly global pandemics and annoying infections. But the pathogens we haven't had to reckon with as much—yet—are the fungi......»»
UV lamps used for disinfection may impair indoor air quality
Using ultraviolet germicidal radiation (UVGI) to disinfect indoor spaces is a demonstrably effective way of deactivating various pathogens (including the SARS-CoV-2 coronavirus). It deactivates bacteria and viruses by exposing them to high-energy UV.....»»
A promising drug target in the fight against drug-resistant fungal infections
Developing new antifungal treatments is a rising health priority due to an alarming rise in multidrug-resistant fungal "superbugs" that evade medications clinicians have relied on for decades......»»
Host-cell factors involved in COVID-19 infections may augur improved treatments
Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human lung cells, identifying a key host-cell player that may prove a new and enduring therapeutic.....»»
"Living medicine" created to tackle drug-resistant lung infections
Researchers have designed the first "living medicine" to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria that is naturally resistant to many types of antibiotics and is a common source of infections in hospital.....»»
RNA lipid nanoparticle engineering stops liver fibrosis in its tracks, reverses damage
Since the success of the COVID-19 vaccine, RNA therapies have been the object of increasing interest in the biotech world. These therapies work with your body to target the genetic root of diseases and infections, a promising alternative treatment me.....»»