Antibiotics for appendicitis
Antibiotics are now an accepted first-line treatment for most people with appendicitis, according to final results of the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) trial, and an updated treatment guideline for appendicitis from t.....»»
Human histones show promise in fighting bacterial infections
Antibiotics have saved millions of lives from infectious diseases and are considered one of the most important discoveries of the 20th century. However, as the use (and abuse) of antibiotics has increased over the years, many bacteria have developed.....»»
Study reveals superbug MRSA"s double defense against antibiotics
Scientists have discovered the mechanism which allows the superbug methicillin resistant Staphylococcus aureus (MRSA) to become highly resistant to antibiotics, paving the way for new approaches to control infectious disease......»»
Using machine learning to identify bacterial resistance genes and the drugs to block them
Antibiotic resistance is a growing public health problem around the world. When bacteria like E. coli no longer respond to antibiotics, infections become harder to treat......»»
Scientists describe how mycobacteria evade the effects of antibiotics
One of the main challenges of contemporary medicine is posed by the resistance of pathogens to antibiotics. An important step in countering it has now been made by researchers from IOCB Prague, in collaboration with colleagues from the Institute of M.....»»
Researchers show nanoplastics can reduce the effectiveness of antibiotics
In a recent study, an international research team with significant involvement from MedUni Vienna has investigated how nanoplastic particles deposited in the body affect the effectiveness of antibiotics......»»
Bacterial pathogen must balance between colonizing airways and developing antibiotic tolerance, study reveals
Imagine trying to settle into a new home while constantly being attacked. That's what the bacterium Pseudomonas aeruginosa faces when it infects the lungs, and it can't both spread and protect itself from antibiotics at the same time......»»
Nanomedicine advances deliver precise antibiotic doses to fight infections and drug resistance
Researchers from the University of Waterloo have developed a new technology that can hold an entire course of antibiotics in one tiny dose and deliver on demand just the right amount of medication that a particular patient needs to fight an infection.....»»
Researcher finds special proteins are key when antibiotic resistance spreads
Antibiotic resistance is a growing public health problem globally. The problem is exacerbated by the fact that some bacteria that have become resistant to antibiotics have the ability to spread that resistance to other bacteria via secretion systems......»»
Targeting "selfish" bacteria could optimize inhibitors that fight antibiotic resistance
As strains of pathogens resistant to frontline antibiotics become more common worldwide, clinicians are more often turning to combination treatments that degrade this resistance as a first treatment option......»»
Barnacle-inspired polymers could present new way to design antibiotics, researchers say
Scientific literature has shown that barnacles that cling to rocks at the seashore use naturally occurring chemicals to clear rock surfaces of bacteria in preparation for laying down their sticky "glue." Since bioengineering professor Abraham Joy's l.....»»
Research team develops metallodrug-antibiotic combination strategy to combat superbugs
Antimicrobial resistance (AMR) bacterial infections have become a serious problem threatening human health worldwide. The overuse of antibiotics has promoted drug-resistant mutations in bacteria, causing almost all clinically used antibiotics to deve.....»»
Genome sequence analysis identifies new driver of antimicrobial resistance
Antibiotics are a lifesaving tool. Yet, due to their chronic overuse, microbes are evolving and developing immunity against them. As a result, once-effective medications can no longer stave off infections, complicating treatment and increasing mortal.....»»
Harnessing nature"s rhythm: Piezocatalysis for organic pollutant degradation
With the rapid growth of industrial and agricultural activities, water bodies are increasingly contaminated with harmful organic pollutants such as dyes, antibiotics, and bisphenol A. Traditional methods like adsorption, chemical treatments, and biol.....»»
Scientists identify 18 bacterial strains to treat antibiotic-resistant gut infections
Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time. Gram-negative bacteria such as Enteroba.....»»
Crispr-Enhanced Viruses Are Being Deployed Against UTIs
With antibiotics losing their effectiveness, one company is turning to gene editing and bacteriophages—viruses that infect bacteria—to combat infections......»»
Promising antibiotic candidates discovered in microbes deep in the Arctic Sea
Antibiotics are the linchpin of modern medicine: without them, anyone with open wounds or needing to undergo surgery would be at constant risk of dangerous infections. Yet we continue to face a global antibiotics crisis, as more and more resistant st.....»»
Mining the microbiome: Uncovering new antibiotics inside the human gut
The average human gut contains roughly 100 trillion microbes, many of which are constantly competing for limited resources. "It's such a harsh environment," says César de la Fuente, Presidential Assistant Professor in Bioengineering and in Chemical.....»»
Peering into the mind of artificial intelligence to make better antibiotics
Artificial intelligence (AI) has exploded in popularity. It powers models that help us drive vehicles, proofread emails and even design new molecules for medications. But just like a human, it's hard to read AI's mind......»»
Surprise finding in study of environmental bacteria could advance search for better antibiotics
In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial.....»»
Could manure and compost act like probiotics, reducing antibiotic resistance in urban soils?
Urban soils often contain chemical contaminants, such as heavy metals or trace amounts of antibiotics, along with higher levels of antibiotic-resistant bacteria. New research from the University of Maryland suggests that, in some cases, boosting urba.....»»