Alzheimer"s disease causes cells to overheat and "fry like eggs"
Researchers have shown that aggregation of amyloid-beta, one of two key proteins implicated in Alzheimer's disease, causes cells to overheat and "fry like eggs.".....»»
Hormone receptor structure reveals how it functions in heart disease
Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering how it functions, which may enable better drug targeting of the receptor for diseases such as.....»»
Genes of ancient animal relatives used to grow a mouse: Study reveals hidden history of stem cells
An international team of researchers has achieved an unprecedented milestone: the creation of mouse stem cells capable of generating a fully developed mouse using genetic tools from a unicellular organism, with which we share a common ancestor that p.....»»
Study uncovers role of tissue viscoelasticity in cell response
To the casual eye, a memory foam mattress would appear to have no relationship to the behavior of cells and tissues. But an innovative study carried out at the Centro de Investigaciones Cardiovasculares (CNIC) in Madrid shows that viscoelasticity—t.....»»
Cross-species transplantation: Generation of rat offspring from ovarian oocytes in mice
The idea of maturing oocytes in the ovary to produce offspring has been implemented in various ways. One such method, ovarian transplantation, is a relatively simple procedure for obtaining eggs, compared to in vitro culture of ovaries and follicles......»»
The First Crispr Treatment Is Making Its Way to Patients
It’s been a year since the gene-editing treatment Casgevy was approved for sickle cell disease and a related blood disorder. It’s finally being infused into patients......»»
What Bird Flu in Wastewater Means for California and Beyond
Wastewater in several Californian cities, including San Francisco and Los Angeles, recently tested positive for bird flu. But understanding disease risk and exposure to humans isn’t so straightforward.....»»
Using genetic code expansion to study membrane proteins
Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it possible to modify proteins directly in living cells to giv.....»»
Which animals carry mpox? Our study identified African forest dwelling rodents as one source
Mpox is a disease caused by the highly infectious monkeypox virus. It's quite easily passed on from one person to another. But it originally came from infected animals......»»
Bone Marrow Donors Can Be Hard to Find. One Company Is Turning to Cadavers
San Francisco–based Ossium Health has carried out three transplants for cancer patients using stem cells from deceased donors’ bone marrow in recent months......»»
Researchers Give Animal Cells the Ability to Photosynthesize for the First Time
A Japanese team has developed a technique to insert chloroplasts isolated from algae into animal cells, a feat that could revolutionize sustainable energy and how artificial meat and organs are created......»»
Squishy microgels in granular biomaterials confine and direct cell behavior
A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State......»»
Simple model system can break down fibrils to investigate drugs for neurodegenerative diseases
The origin of many diseases such as Alzheimer's or Parkinson's can be found at the molecular level in our body, in other words, in proteins. In a healthy system, these proteins are responsible for numerous physiological functions......»»
Four out of five people in Africa use wood for cooking. A transition would cut emissions and save lives
Four in every five people in Africa cook using wood, charcoal and other polluting fuels in open fires or inefficient stoves. This releases harmful pollutants and leads to respiratory illnesses and heart disease, particularly among children......»»
From pets to pests: Researchers explore new tool to fight disease-carrying insects
Arkansas researchers are testing a product commonly used to treat ticks and fleas on pets to target fly and mosquito larvae with the goal of helping reduce the spread of diseases carried by these insects......»»
High-performance inkjet print head enhances bioprinting productivity
Bioprinting is a technology used to create three-dimensional structures, such as human tissues or organs, using bio-inks made of cells and hydrogels. However, conventional inkjet technology has difficulty dispensing bio-inks that are sensitive to tem.....»»
Using CRISPR to decipher whether gene variants lead to cancer
In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the genetic material of living organisms. One application is in cell therapy: A patient's immune cells can be specifically reprogramm.....»»
New strategies needed to combat immune system-damaging poultry virus detected on UK farms
Researchers working to understand the prevalence of a virus that can severely damage the immune system of chickens have said that new strategies are needed to improve the control of the disease in the UK......»»
New CRISPR system for gene silencing doesn"t rely on cutting DNA
Scientists from Vilnius University's (VU) Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA. This research, led by Prof. Patrick Pausch and published in the journal Nature Communications,.....»»
Smart surveillance system improves tomato plant monitoring with high-speed disease detection, fruit counting
Tomatoes are a critical source of nutrients and remain one of the most widely cultivated fruits globally. However, intensive greenhouse practices increase susceptibility to diseases, which can reduce yields by up to 30% and degrade fruit quality......»»
New AI model improves prediction power for genomics related to disease
To understand the workings of DNA in relation to disease, scientists at Los Alamos National Laboratory have developed the first multimodal deep learning model of its kind, EPBDxDNABERT-2, capable of ascertaining the precise relationship between trans.....»»