AI in Medicine Is Overhyped
AI models for health care that predict disease are not as accurate as reports might suggest. Here’s why......»»
Keeping Vilsmeier reagent in the flow: From toxin to medicine in one go
The Vilsmeier reagent is necessary for producing a large range of pharmaceuticals, but its unstable nature and toxic precursor phosgene are challenges for its use. A new process that efficiently produces phosgene, the Vilsmeier reagent and the desire.....»»
Veterinarians developing frailty instrument to personalize canine geriatric care
In human medicine, the ability to measure frailty is a vital aspect of geriatric care. Doctors may recommend one treatment over another based on an elderly person's frailty score, and nursing homes may adjust care protocols as frailty increases......»»
The spectacular downfall of a common, useless cold medicine
This week's unanimous vote on phenylephrine's ineffectiveness was decades in the making. Enlarge / A box of Sudafed PE sinus pressure and pain medicine containing phenylephrine is displayed for sale in a CVS Pharmacy store in Haw.....»»
Farmer behavior found to play a crucial role in managing livestock diseases
A study published in Preventive Veterinary Medicine has shown how differences in farmer behavior can affect controlling the scale of disease outbreaks. Farmer behavior, especially vaccine uptake or other preventative measures, is critical to how effe.....»»
Synthesis of nanoparticles by microorganisms: Exploring the green power of fungi
They are used as medicines, drug carriers and to combat microbes in hospitals, destroy plant pathogens and reduce the amount of traditional fertilizers used in agriculture—nanoparticles are taking over medicine and the agri-food industry......»»
Scientists unlock secrets of red blood cell transporter, potentially paving the way for new drugs
Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs. Details on the findings, which were reported in the September 7 issue of Natur.....»»
"Monstrous births" and the making of race in the nineteenth-century United States
From the Middle Ages to the Enlightenment, "monstrous births"—malformed or anomalous fetuses—were, to Western medicine, an object of superstition. In 19th-century America, they became instead an object of the "modern scientific study of monstrosi.....»»
Newly-engineered versions of bacterial enzyme reveal how antibiotics could be more potent
Modern medicine depends on antibiotics to treat infections by disabling targets inside bacterial cells. Once inside these cells, antibiotics bind to certain sites on specific enzyme targets to stop bacterial growth. Randomly occurring changes (mutati.....»»
Study finds how some ion channels form structures permitting drug delivery
A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill Cornell Medicine. The discovery is a significant ad.....»»
The Battle Against the Fungal Apocalypse Is Just Beginning
Fungal infections are rising worldwide and climate change may be to blame. Medicine isn’t ready......»»
Study supports strong link between respiratory and digestive diseases in dogs
While the respiratory and digestive systems of canines have previously been studied independently, researchers at the University of Missouri College of Veterinary Medicine (CVM) have been investigating the interplay between disorders in either of the.....»»
Serum amyloid A: Exploring links between the beneficial and pathologic actions of an enigmatic protein
Serum amyloid A (SAA) is a family of ancient proteins that can be traced from present-day humans back half a billion years to sea cucumbers and oysters. A new study by researchers from the Boston University Chobanian & Avedisian School of Medicine ex.....»»
Poll shows who Americans trust (and don"t trust) for health news
Misinformation about health and medicine is rampant in the United States, with far too many Americans being presented false claims and left wondering what to believe, a new survey reports......»»
Using starch as a novel drug transporter
A special type of starch could soon be used as an excipient in medicine to improve the treatment of patients. A research team from Martin Luther University Halle-Wittenberg (MLU) has discovered that it makes a suitable drug release system and has adv.....»»
Discovery of chikungunya virus"s "invisibility shield" may lead to vaccines or treatments
Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell—perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, c.....»»
Institutions with strong engineering operations are more efficient in producing patents, researchers find
When it comes to translational medicine, Robert Gourdie is among the 2% of "super-producers," National Institutes of Health-funded scientists at U.S. biomedical institutions who hold 10 or more issued patents......»»
Mitochondria regulate cellular signaling for proper lung development, research finds
Northwestern Medicine investigators have discovered that mitochondria regulate essential cellular signaling for the development of epithelial cells in the lungs, cells which are crucial for the exchange of oxygen and carbon dioxide to avoid respirato.....»»
Ovarian cancer: New biological markers found that may predict which patients won"t respond to chemotherapy
Using a novel proteogenomic strategy and a variety of machine learning tools, investigators from the Icahn School of Medicine at Mount Sinai and colleagues have identified a 64-protein signature that may predict a subset of ovarian cancer patients wh.....»»
Researchers use quantum circuit to identify single nucleotides
DNA sequencing technology, i.e., determining the order of nucleotide bases in a DNA molecule, is central to personalized medicine and disease diagnostics, yet even the fastest technologies require hours, or days, to read a complete sequence. Now, a m.....»»
Scientists develop in vivo RNA-based gene editing model for blood disorders
In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene edi.....»»