AI generates proteins with exceptional binding strengths
A new study in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring. Scientists at the Institute for Protein Design at the University of Washington School of Medi.....»»
RNA editing plays critical role in fruit flies" sense of smell and social interactions
Imagine your DNA as a set of instructions or a recipe book that tells your body how to make everything it needs to function, from proteins to cells. Every time the body needs to build something, it reads these instructions. But sometimes, the body ca.....»»
Mass cytometry barcoding strategy offers a new perspective of non-specific binding
Non-specific binding (NSB), the most annoying thing to scientists in the biosensing field, is one of the main factors limiting the performance of diagnostic sensors......»»
Cells use alternative splicing to regulate gene expression, research suggests
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism increases the diversity of proteins that can be generat.....»»
AI tool maps out cell metabolism with precision
Understanding how cells process nutrients and produce energy—collectively known as metabolism—is essential in biology. Modern biology generates large datasets on various cellular activities, but integrating and analyzing the vast amounts of data.....»»
Protein mutant stability can be inferred from AI-predicted structures
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»
Study finds flexibility and helical twists of actin filaments regulate actin-binding proteins
Researchers at Kanazawa University have published an article in eLife deciphering the actin structure-dependent preferential cooperative binding of cofilin......»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
3D shapes of viral proteins point to previously unknown roles
Viruses are tricky to keep up with. They evolve quickly and regularly develop new proteins that help them infect their hosts. These rapid shifts mean that researchers are still trying to understand a multitude of viral proteins and precisely how they.....»»
Tomato ripening study highlights cell wall component interactions
Tomato fruit ripening involves intricate biochemical and structural changes, particularly within the cell wall, which are vital for the fruit's final texture and quality. These changes include modifications in polysaccharides and proteins, but the sp.....»»
Experts meet as final global plastic treaty talks near
With months until crunch talks on the world's first binding treaty on plastic pollution, experts are meeting in Bangkok to discuss financing options and problematic plastics......»»
The phenomenal AWOL Vision LTV-3500 Pro projector is $700 off today
Best Buy has reduced the price of the exceptional AWOL Vision LTV-3500 Pro projector making it a more tempting proposition......»»
Flooding: Is it time to stop living in basements?
Repeated flooding is neither inevitable nor exceptional. Whether it's the result of a river overflowing, torrential rain or even a failure in the water supply network, flooding has become part of our daily lives......»»
Canadian government intervenes in railway labor dispute
Federal Labor Minister Steven MacKinnon to use powers under Section 107 of the Labor Code to ask the Canada Industrial Relations Board to impose final, binding arbitration.....»»
Ancient microbes linked to evolution of human immune proteins
When you become infected with a virus, some of the first weapons your body deploys to fight it are those passed down to us from our microbial ancestors billions of years ago. According to new research from The University of Texas at Austin, two key e.....»»
Proteins for skin strength also control cell signaling, study suggests
An extensive family of proteins that gives human skin mechanical strength also appears to organize molecular signals that control skin cell activity, a study led by UT Southwestern Medical Center researchers shows. The team's findings, published in D.....»»
Researchers teach artificial intelligence about frustration in protein folding
Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict.....»»
Unveiling the intricate and subtle dance of proteins: Understanding how parasites disarm host defenses
Pathogens hijack host cell functions by expressing or secreting effector proteins, creating environments conducive to their survival and reproduction. These pathogenic microorganisms—including eukaryotic parasites, prokaryotic bacteria, and viruses.....»»
U.S. has its first national strategy to reduce plastic pollution—three strong points and a key issue to watch
Plastic waste is piling up at a daunting pace around the world. The World Bank estimates that every person on the planet generates an average of 1.6 pounds (0.74 kilograms) of plastic waste daily......»»
New AI tool captures how proteins behave in context
A fish on land still waves its fins, but the results are markedly different when that fish is in water. Attributed to renowned computer scientist Alan Kay, the analogy is used to illustrate the power of context in illuminating questions under investi.....»»