ACE-ing protein detection in single cells
Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals. This has enabled a much deep.....»»
Protein USP50 identified as key in DNA replication balance
A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study......»»
Expansion in situ genome sequencing innovation makes hidden DNA-protein interactions visible
Harvard scientists have unveiled a new technique called expansion in situ genome sequencing (ExIGS) that combines existing in situ genome sequencing (IGS) with expansion microscopy (ExM). The innovation allowed researchers to link nucleus abnormaliti.....»»
LIGO team enhances gravitational wave detection with squeezed light
A team of researchers at the Laser Interferometer Gravitational-Wave Observatory (LIGO), in the U.S., has developed what they describe as a squeezed light system to improve detection sensitivity......»»
Cells From Different Species Can Exchange ‘Text Messages’ Using RNA
Long known as a messenger within cells, RNA is increasingly seen as life’s molecular communication system—even between organisms widely separated by evolution......»»
Ammonia fuel cells see performance gains with new catalyst layer
The pursuit of clean and efficient energy conversion technologies has led to significant advancements in fuel cell research. A study conducted at Fuzhou University and published in Frontiers in Energy, presents a novel approach to enhance the perform.....»»
Scientists develop a new method to study gene function in cells and tissue
The Gaublomme lab has developed a new optical pooled screening approach called CRISPRmap, which enables the coupling of optical properties of single cells to targeted genetic perturbations. Optical phenotypes are typically inaccessible for sequencing.....»»
Apple @ Work: Initial macOS Sequoia release broke networking for security and VPN tools – who’s responsible?
Apple @ Work is exclusively brought to you by Mosyle, the only Apple Unified Platform. Mosyle is the only solution that integrates in a single professional-grade platform all the solutions necessary to seamlessly and automatically deploy, manage & pr.....»»
Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry
The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology's biggest challenges: predicting the 3D shape of proteins and designing them from scratch......»»
Targeting "undruggable" diseases: Researchers reveal new levels of detail in targeted protein degradation
Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called protein degraders which can be deployed to combat what have previously been regarded as "undruggable" diseases, including cancers and ne.....»»
Study proposes that proteins can compartmentalize and form droplets inside cells
In physics, a system composed of two substances can be modeled in accordance with classical mixture theory, which considers the fraction corresponding to each constituent and the interactions among constituents. Examples include the coexistence of hi.....»»
Plant stem cells: Understanding the biological mechanism of growth control
Researchers from the University of Freiburg have identified the HAN molecule as an important regulator that controls plant growth in conjunction with WOX5. Understanding this mechanism is relevant for breeding more resilient or higher-yielding crops......»»
Oxidative stress: How protein recycling protects against cell death
Researchers at LMU University Hospital have discovered a new molecular switch that protects against cell death......»»
A quantum material could be the future of high-energy X-ray imaging and particle detection
Scintillators are detectors that make high-energy X-rays or particles visible through flashes of light to form an image. Their many applications include particle physics, medical imaging, X-ray security and more......»»
Scientists discover how innate immunity envelops bacteria
The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now......»»
Expansion technique to image nanoscale structures inside cells makes high-resolution imaging more accessible
A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before imaging it—a technique that allows them to achieve.....»»
Audi Tysons Corner named 2024 Best Dealership To Work For
The 2024 Automotive News Best Dealerships To Work For program includes new categories such as Best Single-Point Dealerships and Best Rural Dealerships......»»
Claustrophobic cells slow their own growth, forming beautiful patterns of concentric circles
Like so many organisms on the planet, when cells experience mosh-pit-level crowding, they may just become stressed. Yet unlike most other life forms, cells subject to physical stress from crowding by neighbors can find some relief by dramatically slo.....»»
Advanced model predicts gene architecture via nucleosome position
DNA—the molecule that carries the genetic information of all living organisms—is packaged within cells in a complex manner that allows it to function efficiently. Nucleosomes facilitate DNA compaction and also play a crucial role in regulating ge.....»»
From chaos to structure: How a bunch of seemingly disorganized cells go on to form a robust embryo
Pipetting liquids into tiny test tubes, analyzing huge datasets, poring over research publications—all these tasks are part of being a scientist. But breaking this routine is essential. Time away from the usual work environment can spark creative i.....»»
AI-driven approach challenges traditional views on protein structure
In a recently published article in Nature Communications,, a team offers an AI-driven approach to explore structural similarities and relationships across the protein universe. The team includes members from the University of Virginia—including Phi.....»»