A new twist: The molecular machines that loop chromosomes also twist DNA
Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor protei.....»»
Ancient DNA sheds light on adaptation of early Europeans at the dawn of the agricultural revolution
Leveraging a unique statistical analysis and applying it to ancient DNA extracted from human skeletal remains, a team of researchers from The University of Texas at Austin and the University of California, Los Angeles has revealed new insights into h.....»»
Advancements in genomic research reveal alternative transcription initiation sites in thousands of soybean genes
Rosalind Franklin, James Watson and Francis Crick discovered the structure of DNA—that molecular blueprint for life—over 70 years ago. Today, scientists are still uncovering new ways to read it......»»
Microsoft plans to boot security vendors out of the Windows kernel
Microsoft has announced the Windows Resiliency Initiative, aimed at avoiding a repeat of the prolonged worldwide IT outage caused by a buggy CrowdStrike update that took down millions of Windows machines and rendered them remotely unfixable. As part.....»»
Seemingly "broken" genes in coronaviruses may be essential for viral survival
Viruses are lean, mean, infection machines. Their genomes are tiny, limited to a handful of absolutely essential genes, and they shed extra genomic deadweight extremely fast... usually......»»
PSA: M4 Macs can’t run virtual machines with older versions of macOS
iMac and , which brings a lot of performance improvements – especially when it comes to AI tasks. However, users are facing issues when trying to run virtual machines with some older versions of macOS on the new machines. more….....»»
iPhone 17 rumors: A19 chip details, smaller Dynamic Island, more
Apple analyst Jeff Pu is out with a new investor note this week with more details on what to expect from next year’s iPhone 17 lineup. There’s also an interest twist on what to expect from the so-called iPhone 17 Air’s design… more….....»»
Researchers characterize regulating mechanism of orderly zygotic genome activation in early embryos
Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA). Recent work by Chinese scientists has revealed a novel molecular.....»»
Chicago-area water pollution may be stalling the spread of invasive carp
In a name-your-poison twist, a new study from the University of Illinois adds to the evidence that Chicago-area waterway pollution is slowing the relentless advance of the invasive silver carp......»»
How marine worms regenerate lost body parts: Return of cells to stem cell-like state could be key
Many living organisms are able to regenerate damaged or lost tissue, but why some are particularly good at this and others are not is not fully understood. Molecular biologists Alexander Stockinger, Leonie Adelmann and Florian Raible from the Max Per.....»»
Archaea shape microbiomes by using molecular spring-loaded daggers
In a paper published in Science Advances, the Pilhofer Lab (IMBB) together with the Albers Lab from the University of Freiburg describe the structure and function of contractile injection systems from haloarchaea and show how it can structure the loc.....»»
Age on the molecular level: Research analyzes quantitative changes in a wide range of proteins
With the worldwide population aging at an unprecedented rate, the prevention of age-related diseases has become a prominent issue. It is important to comprehensively and quantitatively evaluate the changes that aging causes at the molecular level in.....»»
How to Design a Real-Life Hot Wheels Loop
You should absolutely not build this thing. But it’s still fun to think through the physics......»»
Theoretical model explains the anomalous properties of water in extreme conditions
Water, a molecule essential for life, has unusual properties—known as anomalies—that define its behavior. However, there are still many enigmas about the molecular mechanisms that would explain the anomalies that make the water molecule unique. D.....»»
Rue Valley puts a time loop spin on Disco Elysium
Rue Valley is the latest video game to utilize a time loop hook, applying that structure to a Disco Elysium-like RPG......»»
Simple model system can break down fibrils to investigate drugs for neurodegenerative diseases
The origin of many diseases such as Alzheimer's or Parkinson's can be found at the molecular level in our body, in other words, in proteins. In a healthy system, these proteins are responsible for numerous physiological functions......»»
Solving the bottleneck of conifer propagation: A molecular approach
Conifers are foundational to ecosystems globally, providing critical environmental and economic value. Yet, their long life cycles slow traditional breeding methods, positioning somatic embryogenesis (SE) as a more effective option for rapid propagat.....»»
New CRISPR system for gene silencing doesn"t rely on cutting DNA
Scientists from Vilnius University's (VU) Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA. This research, led by Prof. Patrick Pausch and published in the journal Nature Communications,.....»»
New AI model improves prediction power for genomics related to disease
To understand the workings of DNA in relation to disease, scientists at Los Alamos National Laboratory have developed the first multimodal deep learning model of its kind, EPBDxDNABERT-2, capable of ascertaining the precise relationship between trans.....»»
An AI robot’s painting just auctioned for more than $1 million
Sotheby's said the sale puts the artwork among those of famed artists past and present, and marks a shift where machines are now part of the creative process......»»
New DNA evidence rewrites long-told stories of people in ancient Pompeii
When a volcanic eruption buried the ancient city of Pompeii, the last desperate moments of its citizens were preserved in stone for centuries......»»