A mitochondria-targeted fluorescent probe for cisplatin
NUS chemists have developed a mitochondria-targeted fluorescent probe for real-time imaging of clinically important anticancer drug cisplatin in live cancer cell models......»»
New time-resolved ultraviolet photodissociation mass spectrometry strategy for target protein stability analysis
How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle structure dynamics is st.....»»
Judge halts Texas probe into Media Matters’ reporting on X
Texas attorney general remained silent on claims of First Amendment retaliation. Enlarge / Texas Attorney General Ken Paxton speaks during the annual Conservative Political Action Conference (CPAC) meeting on February 23, 2024. (.....»»
Formation-flying spacecraft could probe the solar system for new physics
It's an exciting time for the fields of astronomy, astrophysics, and cosmology. Thanks to cutting-edge observatories, instruments, and new techniques, scientists are getting closer to experimentally verifying theories that remain largely untested. Th.....»»
NASA unveils probe bound for Jupiter"s possibly life-sustaining moon
US space scientists on Thursday unveiled the interplanetary probe NASA plans to send to one of Jupiter's icy moons as part of humanity's hunt for extra-terrestrial life......»»
Study finds that anti-Jewish and anti-Muslim accounts have grown on Elon Musk"s X
Since the war in Gaza, accounts spreading conspiracy theories and targeted hate speech have grown on Twitter/X. Since the escalation of the ongoing war on Gaza and in the age of Elon Musk's X/Twitter takeover, anti-Jewish and anti-Muslim hate s.....»»
Scientists find new ways to convert inhibitors into degraders, paving the way for future drug discoveries
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells......»»
Scientists reconstruct assembly of the human centriole, image by image, for the first time
Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as "organelles." Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to.....»»
New molecular device unlocks potential for targeted drug delivery and self-healing materials
In a new breakthrough that could revolutionize medical and material engineering, scientists have developed a first-of-its-kind molecular device that controls the release of multiple small molecules using force......»»
IT pros targeted with malicious Google ads for PuTTY, FileZilla
An ongoing malvertising campaign is targeting IT administrators looking to download system utilities such as PuTTY (a free SSH and Telnet client) and FileZilla (a free cross-platform FTP application). “We have reported this campaign to Google b.....»»
Upcoming report on the state of cybersecurity in Croatia
Next week, Diverto is set to release a comprehensive report on Croatia’s cybersecurity landscape. This report will provide a detailed summary of the key events from 2023, offer targeted recommendations for managerial strategies, and highlight c.....»»
A targeted polymer to treat colorectal cancer liver metastases
A nanosized polymer, developed by a research team from Ben-Gurion University of the Negev, can selectively deliver chemotherapeutic drugs to blood vessels that feed tumors and metastases and has emerged as an effective treatment for advanced cancer......»»
Researchers map structure of mitochondria at different life stages
Mitochondria, organelles with an inner and outer membrane, are responsible for creating the energy that cells use to survive, and their morphology is key to accomplishing this task. The inner mitochondrial membrane contains folds, called cristae, tha.....»»
NASA knows what knocked Voyager 1 offline, but it will take a while to fix
"Engineers are optimistic they can find a way for the FDS to operate normally." Enlarge / A Voyager space probe in a clean room at the Jet Propulsion Laboratory in 1977. (credit: Space Frontiers/Archive Photos/Getty Images).....»»
Google sues two crypto app makers over allegedly vast “pig butchering” scheme
Crypto and other investment app scams promoted on YouTube targeted 100K users. Enlarge (credit: NurPhoto / Contributor | NurPhoto) Google has sued two app developers based in China over an alleged scheme targeting 100,00.....»»
Fake AI law firms are sending fake DMCA threats to generate fake SEO gains
How one journalist found himself targeted by generative AI over a keyfob photo. Enlarge / A person made of many parts, similar to the attorney who handles both severe criminal law and copyright takedowns for an Arizona law firm......»»
F-150 Lightning EV targeted by climate protesters at New York auto show
Video shows onlookers heavily booing the protesters, one of whom was carrying a tote bag from the Toyota stand......»»
Japan moon probe put to sleep again
Japan's valiant moon lander was put to sleep again after unexpectedly surviving its second ultra-chilly long lunar night, the space agency said Monday......»»
Unlocking insights into marketing to mature consumers: A new research synthesis
Research from Queen Mary University of London academic Dr. Mina Tajvidi, delves into marketing communications targeted at mature consumers aged 50 and above, addressing definitional inconsistencies and reviewing research published since 1972......»»
ESA and NASA team up to study solar wind
In the run up to April's total solar eclipse, ESA-led Solar Orbiter and NASA-led Parker Solar Probe are both at their closest approach to the sun. Tomorrow (March 29), they are taking the opportunity to join hands in studying the driving rain of plas.....»»
Japan moon probe survives second lunar night
Japan's moon lander woke up after unexpectedly surviving a second frigid, two-week lunar night and transmitted new images back to Earth, the country's space agency said Thursday......»»