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Structure-destabilizing mutations transform Bcl-2 from an antiapoptotic protein into a proapoptotic protein

Bcl-2 family proteins are highly conserved molecules that play a crucial role in regulating the release of apoptotic proteins from mitochondria. They possess Bcl-2 homology (BH) domains, which are characterized by both sequence and structural similar.....»»

Category: topSource:  physorgOct 19th, 2023

Researchers develop bioinspired Bouligand structure for enhanced mechanical properties

Bouligand structures, found in natural materials like fish scales, lobster peritoneum and bones, are known for providing exceptional mechanical properties to biomaterials. While progress has been made in creating bioinspired materials, most research.....»»

Category: topSource:  physorgRelated NewsMay 7th, 2024

Bio-inspired materials" potential for efficient mass transfer boosted by a new twist on a century-old theory

The natural vein structure found within leaves—which has inspired the structural design of porous materials that can maximize mass transfer—could unlock improvements in energy storage, catalysis, and sensing thanks to a new twist on a century-old.....»»

Category: topSource:  physorgRelated NewsMay 7th, 2024

Elastic’s Search AI to transform SOCs with AI-driven SIEM solutions

Elastic has announced that Search AI will replace the traditional SIEM with an AI-driven security analytics solution for the modern SOC. Powered by the Search AI platform, Elastic Security is replacing largely manual processes for configuration, inve.....»»

Category: securitySource:  netsecurityRelated NewsMay 7th, 2024

Researchers explore raw materials and firing technology for porcelain from late sixth-century Xing kiln

In the process of firing ceramics, the appearance, structure and properties of ceramics are determined by raw materials and firing technology, so the study of raw materials and firing technology of ancient ceramics has always been a very important ar.....»»

Category: topSource:  physorgRelated NewsMay 6th, 2024

Scientists use high pressure NMR spectroscopy to study structure of dynamic proteins

A pressure of 3,000 bar is applied to the cold shock protein B of Bacillus subtilis in a small tube in the NMR spectroscopy laboratory at the University of Konstanz. This is roughly three times the water pressure at the deepest point of the ocean. Th.....»»

Category: topSource:  physorgRelated NewsMay 6th, 2024

Synthetic chemistry approach yields new compounds with potential biomedical applications

Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes. The molecules found in various living organisms exhibit diverse biological activities, including the ability to modulate protein-protein.....»»

Category: topSource:  physorgRelated NewsMay 6th, 2024

New discovery of a mechanism that controls cell division

Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Researchers detect toxic chemicals in aquatic organisms with new AI method

Swedish researchers at Chalmers University of Technology and the University of Gothenburg have developed an AI method that improves the identification of toxic chemicals—based solely on knowledge of the molecular structure......»»

Category: topSource:  physorgRelated NewsMay 2nd, 2024

Proofpoint DLP Transform secures data moving to ChatGPT, copilots, and other GenAI tools

Proofpoint announced Data Loss Prevention (DLP) Transform, including GenAI use cases. Today, businesses struggle with the limitations of legacy DLP solutions that are fragmented across channels and are not designed to address today’s most problemat.....»»

Category: securitySource:  netsecurityRelated NewsMay 2nd, 2024

Porsche study concludes aluminum could reduce Taycan weight, increase manufacturing simplicity

The study by Alumobility found switching the electric Taycan's top hat structure to all-aluminum could cut down on weight by about 40 percent......»»

Category: topSource:  autonewsRelated NewsMay 1st, 2024

Study is first to describe and recreate lemurs" one-of-a-kind vocal structure

New research has discovered that lemurs, the small primates native to Madagascar, are capable of exaggerating their size thanks to the unique structure of their larynx......»»

Category: topSource:  pcmagRelated NewsApr 30th, 2024

Microgravity-grown crystals reveal new insights into protein structures

Biochemists have long been working around a blind spot when it comes to proteins. They know that hydrogen constitutes nearly half of the atoms in proteins, but how they contribute to protein function in these complex structures has been less clear. H.....»»

Category: topSource:  physorgRelated NewsApr 29th, 2024

Researchers develop tiny droplets that harness laser light to detect disease markers

A team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has created tiny droplets that, when activated by laser light, can detect viral protein biomarkers indicating the presence of certain diseases......»»

Category: topSource:  physorgRelated NewsApr 29th, 2024

Bacteria "nanowires" could help develop green electronics

Engineered protein filaments originally produced by bacteria have been modified by scientists to conduct electricity. In a study published recently in the journal Small, researchers revealed that protein nanowires—which were modified by adding a si.....»»

Category: topSource:  physorgRelated NewsApr 29th, 2024

T. rex not as smart as previously claimed, scientists find

Dinosaurs were as smart as reptiles but not as intelligent as monkeys, as former research suggests. An international team of paleontologists, behavioral scientists and neurologists have re-examined brain size and structure in dinosaurs and concluded.....»»

Category: topSource:  physorgRelated NewsApr 29th, 2024

Researchers decipher how an enzyme modifies the genetic material in the cell nucleus

Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure of the nucleosomes determin.....»»

Category: topSource:  pcmagRelated NewsApr 26th, 2024

Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell

The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»

Category: topSource:  physorgRelated NewsApr 25th, 2024

Scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater

Scientists from Nanyang Technological University, Singapore (NTU Singapore) and Temasek Polytechnic have successfully replaced half of the fishmeal protein in the diets of farmed Asian seabass with a "single cell protein" cultivated from microbes in.....»»

Category: topSource:  physorgRelated NewsApr 25th, 2024

A shade closer to more efficient organic photovoltaics

Transparent solar cells will transform the look of infrastructure by enabling many more surfaces to become solar panels. Now, materials called non-fullerene acceptors that can intrinsically generate charges when exposed to sunlight could make semitra.....»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

Scientists tune the entanglement structure in an array of qubits

Entanglement is a form of correlation between quantum objects, such as particles at the atomic scale. The laws of classical physics cannot explain this uniquely quantum phenomenon, yet it is one of the properties that explain the macroscopic behavior.....»»

Category: topSource:  physorgRelated NewsApr 24th, 2024