Tuberculosis vaccine may enable elimination of the disease in cattle by reducing its spread
Vaccination not only reduces the severity of TB in infected cattle, but reduces its spread in dairy herds by 89%, research finds. The research, led by the University of Cambridge and Penn State University, improves prospects for the elimination and c.....»»
New tuberculosis study offers a novel paradigm for understanding bacterial transcription
The bacterium behind tuberculosis is a wily foe, adept at bobbing and weaving around the immune system and antibiotics alike. Mycobacterium tuberculosis (Mtb) has been notoriously difficult to eradicate, often dormant in the body for years only to re.....»»
U.S. safety protocols stopped TB in imported lab monkeys from spreading to humans
Rigorous safety protocols prevented an outbreak of tuberculosis last year in lab monkeys imported to the United States from spreading to humans, a new report shows......»»
Special publication investigates paleopathology and evolution of tuberculosis
Recent research suggests that the emergence of tuberculosis infection (TB) in human populations dates back tens of thousands of years earlier than previously known cases in the Middle East. In collaboration with an international research team, Hungar.....»»
Battling persistence in tuberculosis bacteria
Researchers at the Indian Institute of Science (IISc), in collaboration with NCBS and InStem, have uncovered an important mechanism that allows the tuberculosis (TB) bacterium to persist in the human host for decades. They found that a single gene in.....»»
Nanoparticles with antibacterial action could shorten duration of tuberculosis treatment
A low-cost technology involving nanoparticles loaded with antibiotics and other antimicrobial compounds that can be used in multiple attacks on infections by the bacterium responsible for most cases of tuberculosis has been developed by researchers a.....»»
Novel compounds show promise in the fight against tuberculosis and neurodegenerative disease
Prof. Bernd Plietker and his research group at the Chair of Organic Chemistry I at TUD have specifically developed a class of natural substances—polyprenylated polycyclic acylphloroglucinols (PPAP for short). Due to its properties, the resulting de.....»»
Daycare TB case exposes over 500 babies, children; emergency declared
The health department has set up multiple clinics to test children as quickly as possible. Enlarge / Mycobacterium tuberculosis. (credit: Getty | NIH/NIAID) Health officials in Omaha, Nebraska, are wasting no time in tes.....»»
How cord-like aggregates of bacteria lead to tuberculosis infections
The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. In a study published October 20 in the journal Cell, investigators report the biophysical mechanisms by wh.....»»
What"s the best way to prevent tuberculosis transmission from wildlife to cattle?
An analysis of relevant published studies indicates that cattle face a hypothetically high risk of getting tuberculosis from wildlife—such as deer, foxes, and wild boar—through indirect interactions, with a much lower risk from direct interaction.....»»
Woman who went on the lam with untreated TB is now out of the slammer
After 23 days in jail, she agreed to take her meds and must open her door to officials. Enlarge / Mycobacterium tuberculosis. (credit: Getty | NIH/NIAID) A woman in Tacoma, Washington, with an infamous case of tuberculos.....»»
Tuberculosis therapy: Smallest particles could deliver drugs to the lungs
Therapy for the dangerous infectious disease of tuberculosis faces the challenge of pathogens frequently being resistant to several common antibiotics. Researchers of Karlsruhe Institute of Technology (KIT) have now developed nanoparticles to deliver.....»»
Woman with untreated TB finally in custody—held in “negative pressure” room
She is being held in a jail room specially equipped for isolation and treatment. Enlarge / Mycobacterium tuberculosis. (credit: Getty | NIH/NIAID) Law enforcement officials in Washington state have finally apprehended a.....»»
Woman with untreated TB still on the lam three months after arrest warrant
"If we knew where she was, she would be in custody." Scanning electron micrograph of Mycobacterium tuberculosis bacteria, which cause TB. (credit: National Institute of Allergy and Infectious Diseases) A woman with an un.....»»
Researchers make significant step in fight against drug resistance in TB
University of Otago researchers have discovered new ways to treat antibiotic-resistant strains of tuberculosis (TB), opening the door to new approaches for tackling the disease that kills about 4,000 people a day......»»
After 17th court hearing, woman with TB ordered to jail for refusing treatment
Washington judge issued an arrest warrant and ordered her to involuntary detention. Enlarge / Mycobacterium tuberculosis. (credit: Getty | NIH/NIAID) A judge in Washington issued an arrest warrant Thursday for a Tacoma w.....»»
Glycerol may jeopardize functional assays, lowering chances of success in drug design campaigns
New antitubercular drugs are vital due to the spread of resistant strains of Mycobacterium tuberculosis. A research team from Skoltech, MIPT, and the Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus (IBOCH NAS) has obt.....»»
Signaling proteins shown to play key role in tuberculosis biology
A set of 10 signaling proteins found in the microbe that causes tuberculosis (TB) play a far larger role in regulating the bacterium's growth, development and behavior than previously thought, according to recent research. The study was led by UW Sch.....»»
Drugs affect individual cells differently, new research suggests
A new state-of-the-art method that measures the amounts of drugs and lipids (fats) in individual cells could help health professionals target more effective treatments for diseases such as tuberculosis (TB)......»»
Scientists reveal flaws in tuberculosis bacterium by studying ferredoxins
Small proteins called ferredoxins play a pivotal role in the main metabolic pathways, the series of chemical reactions occurring within a cell......»»