US woman has walked around with untreated TB for over a year, now faces jail
Recent X-rays of her lungs were so bad, doctors thought she had cancer. Enlarge / Scanning electron micrograph of Mycobacterium tuberculosis bacteria, which cause TB. (credit: Getty | NIH/NIAID) A woman in Washington sta.....»»
New study into tuberculosis membrane molecules could aid drug delivery
A new method to aid in the development of antibiotics for tuberculosis (TB) infections has been devised......»»
Emily Brontë"s death needs to be radically reimagined—an expert explains
Novelist Charlotte Brontë was devastated when her sister Emily died from tuberculosis on December 19, 1848......»»
New DNA analysis provides first accurate tuberculosis genome
Researchers have developed a novel genome assembly tool that could spur the development of new treatments for tuberculosis and other bacterial infections......»»
Scientists reveal protein mechanism behind tuberculosis pathogen success
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a leading infectious threat to public health worldwide. It is estimated to have infected 2–3 billion people and causes ~1.5 million deaths each year......»»
A big step toward treating tuberculosis without risking antibiotic resistance
Tuberculosis, an infectious disease that killed 1.5 million people in 2020, is most commonly treated with a cocktail of four drugs that must be taken for up to six months. This treatment plan, however, can have the unintended consequence of leading t.....»»
Using artificial intelligence to improve tuberculosis treatments
Imagine you have 20 new compounds that have shown some effectiveness in treating a disease like tuberculosis (TB), which affects 10 million people worldwide and kills 1.5 million each year. For effective treatment, patients will need to take a combin.....»»
Bacterial vesicles coated on gold nanoparticles to combat TB
Researchers from the Indian Institute of Science (IISc) have designed a new method to deliver a vaccine candidate for tuberculosis (TB). It involves using spherical vesicles secreted by bacteria coated on gold nanoparticles which can then be delivere.....»»
Working to discover new treatments for tuberculosis
Mycobacterium tuberculosis, the causative agent of tuberculosis, remains the leading cause of infectious disease worldwide, affecting approximately a quarter of the globe's population. Treatment of infections is problematic due to the emergence of dr.....»»
Genetic mutations enable efficient evolution of tuberculosis-causing bacteria
Researchers have identified how the bacterium that causes tuberculosis (TB) can evolve rapidly in response to new environments, according to a study published today in eLife......»»
Pompeii victim had spinal tuberculosis when he died
The study also sequenced the victim's entire genome. Enlarge / This is not what a healthy lumbar vertebra is supposed to look like. (credit: Scorrano et al. 2022) The eruption of Mount Vesuvius buried the Roman city of Pompe.....»»
Tuberculosis Is the Oldest Pandemic, and Poverty Makes It Continue
Tuberculosis is preventable and curable, yet it afflicts one quarter of the world’s population—mostly because of poverty -- Read more on ScientificAmerican.com.....»»
A gene in tuberculosis bacteria is found essential for siderophore secretion and virulence
Lei Zhang, Ph.D., and Michael Niederweis, Ph.D., of the University of Alabama at Birmingham have made what they call "a major step" in understanding how Mycobacterium tuberculosis acquires iron from its human host—a process essential for the pathog.....»»
New discovery may hold key to fighting deadly infections
Centenary Institute research has revealed new insight into tackling mycobacterial infections which are responsible for chronic diseases that include tuberculosis (TB), leprosy and serious skin ulcerations......»»
Asian elephant cured of tuberculosis developed from long-term latency
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). It was the leading cause of human death due to a single pathogen before the emergence of SARS-CoV-2. In elephants, infections and deaths from TB have been reported.....»»
Pathogenic bacteria causing lung diseases hitchhike on red blood cells
Mycobacteria are a group of pathogenic bacteria that cause diseases like leprosy and tuberculosis in humans. Now, a new study by scientists at Hiroshima University finds that mycobacteria are associated with red blood cells at lung infection sites, a.....»»
TB antibiotic activity impacted by cell pH
Researchers at the Francis Crick Institute have shown that an antibiotic used to treat tuberculosis (TB) is affected by pH levels in the environment the bacteria has infected......»»
Exploring ancient tuberculosis transmission chains
Tuberculosis (TB) is the second most common cause of death worldwide by an infectious pathogen (after Covid-19), but many aspects of its long history with humans remain controversial. Researchers at the Max Planck Institute for Evolutionary Anthropol.....»»
How the pathogen Mycobacterium tuberculosis secretes and traffics its only known exotoxin
Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years......»»
Genetic contact tracing could help curb TB
The novel use of genetic contact tracing to identify the source of a bovine tuberculosis outbreak could signal a new approach in managing the disease, a study suggests......»»