Venomous Snail Unlocks New Diabetes Drugs
A cone snail’s poison helps to form a fast-acting insulin -- Read more on ScientificAmerican.com.....»»
New chemical method advances toward targeted RNA medicine
Targeted drugs aim to pinpoint the exact location in the body where diseased tissue is located and where the medicine is required. The manifold benefits of administering a targeted drug include heightened efficacy, as the drug is meticulously designe.....»»
Could the "central dogma" of biology be misleading bioengineers?
Today, medicines based on antibodies—proteins that fight infection and disease—are prescribed for everything from cancer to COVID-19 to high cholesterol. The antibody drugs are supplied by genetically-engineered cells that function as tiny protei.....»»
Researchers compare controlled release of bisphosphonates
Bisphosphonate (BP) drugs are a common treatment strategy to combat calcium-related metabolic disorders, osteoporosis being the most widely known one. These drugs offer several benefits but are plagued by side-effects. One approach to mitigate these.....»»
Researchers discover new way to force pathogenic proteins into degradation
Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great promise in pharmaceutical r.....»»
Catalyst makes drugs inside the body to minimize side effects
A highly active catalyst capable of synthesizing drug molecules within the body has been developed by RIKEN chemists. In mice, an anticancer drug assembled near tumors using the injected catalyst suppressed tumor growth......»»
Researcher characterizes enzymes with N–N bonds for antibacterial applications
The building blocks for new drugs that help fight bacteria that are resistant to known antibiotics, for example, should be as cost-effective and environmentally friendly as possible. Enzymes are ideal for this purpose. For example, they can produce o.....»»
Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain re.....»»
New approach to drug discovery: Developing pain medication with fewer side effects
People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects. Accordingly, in recent years the search for safer alternatives has been the focus of new drug discovery......»»
iOS 17.2 unlocks Qi2 wireless charging support on older iPhone models
iOS 17.2 unlocks a significant new feature for iPhone 13 and iPhone 14 users: support for Qi2 wireless charging. This comes after the iPhone 15 was announced as the first Qi2-enabled iPhone and before the first Qi2 accessories hit the market this mon.....»»
AI model directly compares properties of potential new drugs
Biomedical engineers at Duke University have developed an AI platform that autonomously compares molecules and learns from their variations to anticipate property differences critical to discovering new pharmaceuticals. The platform provides research.....»»
Google Messages Hits 1 Billion RCS Users, Unlocks New Features
Google announced this morning that it has reached 1 billion RCS users in Google Messages, a major milestone, with only more RCS users set to be coming soon. Before we go any further, a round of high fives to all of us for sticking with RCS over the y.....»»
Study: Your local sea snail might not make it in warmer oceans, but oysters will
The frilled dog winkle may sound like a complex knot for a tie, but this local sea snail holds clues to our warmer future, including a dire outlook for species that can't move, adapt, or acclimate as fast as their environment heats up......»»
Genomic studies shed light on the origins of bee venom
Bees, wasps and ants belong to the Hymenoptera order and inject a whole cocktail of venomous ingredients when they sting. Despite their tremendous ecological and economic importance, little was previously known about the origins of their venom......»»
Nanodiamonds can block tumor metastasis in mice, study shows
Nanodiamonds are 2–8 nm carbon nanoparticles, which can be easily functionalized with various chemical groups like carboxylic groups or drugs. Previous research has shown that actively dividing cells are more likely to absorb nanodiamonds and that.....»»
New method for identifying bacteria more easily
Far too many antibiotics are used around the world. As a result, bacteria are becoming resistant to these drugs. Curing bacterial diseases is becoming more difficult than before because antibiotics are perhaps our foremost weapons in the fight agains.....»»
Japanese snail adaptation and speciation in anti-predation escape behavior
Snails often get a bad rap for being slow and inefficient and are sometimes used to express laziness. However, a team of researchers from Kyoto and Hokkaido has now revealed that snails are anything but lazy, particularly when feeling threatened. Two.....»»
New platform solves key problems in targeted drug delivery
In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases. But the lack of effective ways to deliver biological treatments int.....»»
Chemists use oxygen, copper "scissors" to make cheaper drug treatments possible
Drugs to treat cancer are often very expensive to produce, resulting in high costs for the patients who need them. Thanks to pathbreaking research by UCLA chemists, led by organic chemistry professor Ohyun Kwon, the price of drug treatments for cance.....»»
Big Pharma fought drug pricing reform with record $7.5M dark money donation
Dark money group American Action Network spend millions opposing drug pricing reforms. Enlarge (credit: Getty | YinYang) In August, the Department of Health and Human Services announced 10 drugs selected for the first ro.....»»
Team discovers rules for breaking into Pseudomonas
Researchers report in the journal Nature that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that—once it infects a person—is notoriously difficult to treat......»»