This is how the superbug Pseudomonas aeruginosa reacts to antibiotics
The bacterium Pseudomonas aeruginosa is resistant to all antibiotics on the market. Therefore, there is a great need for new therapeutic approaches. In order to find them, it helps to understand how the germ reacts to active substances......»»
Researchers uncover details of how bacteria build protective barriers, may inform new antibiotics
Yale researchers have uncovered new details on how bacteria like E. coli build their protective barriers, which will inform new antibiotic development......»»
Probiotic feed additive, in place of antibiotics, found to boost growth and health in poultry
Antimicrobial resistance is an increasingly serious threat for public health, and the use of antimicrobials in livestock feed has been a major contributing factor in the emergence and spread of antimicrobial resistance to many drugs, according to the.....»»
A new coating method in mRNA engineering points the way to advanced therapies
Medicine can help to treat certain illnesses; for example, antibiotics can help overcome infections, but a new, promising field of medicine involves providing our body with the "blueprint" for how to defeat illnesses on its own......»»
Study describes zinc oxide nanoparticle strategy for inactivation of multidrug-resistant bacteria
An article published in the Journal of Environmental Chemical Engineering describes a possible strategy for promoting selective inhibition of multidrug-resistant bacteria, which are increasingly abundant owing to the indiscriminate use of antibiotics.....»»
New antibiotic class effective against multidrug-resistant bacteria discovered
Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic class is described in an article i.....»»
Fungal resources: Eleven new species of Trichoderma from China
Trichoderma spp. are globally distributed and are considered significant fungal resources. They are widely studied and applied due to their economic and ecological importance, offering numerous benefits, such as producing enzymes and antibiotics, aid.....»»
Gut microbiota and antibiotics: Missing puzzle piece discovered
The intricacies of how intestinal bacteria adapt to their environment have yet to be fully explored. Researchers from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of California, Berkeley, U.S., have.....»»
Researchers invent artificial intelligence model to design new superbug-fighting antibiotics
Researchers at McMaster University and Stanford University have invented a new generative artificial intelligence model that can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory......»»
Research reveals new starting points for the rapid and targeted development of future drugs
Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products of bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools for synthetic biology. By.....»»
New tuberculosis study offers a novel paradigm for understanding bacterial transcription
The bacterium behind tuberculosis is a wily foe, adept at bobbing and weaving around the immune system and antibiotics alike. Mycobacterium tuberculosis (Mtb) has been notoriously difficult to eradicate, often dormant in the body for years only to re.....»»
New starting point discovered in the fight against P. aeruginosa
Pseudomonas aeruginosa is an important opportunistic pathogen responsible for life-threatening infections that are associated with high rates of morbidity and mortality. Researchers from TWINCORE, the Center for Experimental and Clinical Infection Re.....»»
Sugar-coated gold nanoparticles can quickly eliminate bacterial infections, no antibiotics required
If left to their own devices, bacteria on our teeth or wounded skin can encase themselves in a slimy scaffolding, turning into what is called biofilm. These bacteria wreak havoc on our tissue and, being shielded from antibiotic medication by the slim.....»»
Study reveals "considerable farmer knowledge" on aspects of antibiotics risk
A study published in CABI Agriculture and Bioscience has revealed "considerable farmer knowledge" on different aspects of antibiotics risks—including antimicrobial resistance—associated with their use on livestock in Kenya......»»
Blighia sapida: A tropical fruit with antimicrobial properties
Antimicrobial resistance (AMR) remains 1 of the top 3 global public health challenges facing humanity. Every year, 70,000 people die globally from AMR, and the threat is exacerbated by the fact that we have moved from the era of excess antibiotics to.....»»
Researchers focus on finding flaws in superbugs" armor
Recent years have seen the rise of bacterial pathogens that have developed resistance to antibiotics. One such superbug, carbapenem-resistant Acinetobacter baumannii (CRAB), kills hundreds of critically ill patients in the U.S. each year, usually in.....»»
Scientists deliver portable total chemical analysis without pumps and tubes
Researchers from Tokyo Metropolitan University have engineered a new micro total analysis system that quantifies a target chemical in a microfluidic chip without pumps, tubes, and expensive detectors. The compound reacts with other chemicals to produ.....»»
Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
About a decade ago, researchers in UC Santa Barbara chemistry professor Guillermo Bazan's lab began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing th.....»»
Antibiotic use on Kenya"s dairy farms is putting consumers and animals at risk
Farmers often use antibiotics to keep their livestock healthy. They're sometimes used as "quick fixes", to avoid more costly management measures like regular disinfection, waste management, routine vaccination or provision of clean drinking water......»»
A Virus Found in Wastewater Beat Back a Woman’s ‘Zombie’ Bacteria
Viruses called phages are a promising treatment option for bacterial infections when antibiotics stop working, but they have limitations......»»
New research highlights implications of antibiotic use in human and veterinary medicine
A series of five research publications on Antimicrobial Resistance (AMR) by APC Microbiome Ireland yields new data regarding the implications of antibiotic use in early life and the effects of antibiotics in standard dry cow therapy......»»