Thermal fluctuations and oscillation modes found to determine the uptake of bacteria in cells
How and with what effort does a bacterium—or a virus—enter a cell and cause an infection? Researchers from Freiburg have now made an important contribution to answering this question......»»
Compact "gene scissors" enable effective genome editing, may offer future treatment of high cholesterol gene defect
CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissors" but is much smaller and thus easier to transport into cells......»»
Giant panda skin cells transformed into stem cells to help ensure their survival
A team of biologists in China has reprogrammed skin cells from giant pandas into induced pluripotent stem cells (iPSCs), opening the door to creating primordial germ cells that could serve as precursors to sperm and egg cells......»»
Experts discover the deadly genetics of cholera, which could be key to its prevention
Experts have used a cutting-edge computational approach to discover the genetic factors that make the bacteria behind cholera so dangerous—which could be key to preventing this deadly disease......»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
AI tools help uncover enzyme mechanisms for lasso peptides
Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tes.....»»
New data science tool greatly speeds up molecular analysis of our environment
A research team led by scientists at the University of California, Riverside, has developed a computational workflow for analyzing large data sets in the field of metabolomics, the study of small molecules found within cells, biofluids, tissues, and.....»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
How a bacterial pathogen that causes dysentery manipulates molecular activity to assure its survival
Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism. Daniel Capelluto and his research team have discovered the mechanism by which the bacterial pathogen Shigella flexneri, the causative agent of dysen.....»»
First-of-its kind tool allows scientists to manipulate cells without touching them
When studying the spread of cancer or the behavior of a virus like the one that causes COVID-19, the irony is that working with these harmful pathogens requires gentleness. Especially in the case of COVID, the particles do not survive well when makin.....»»
Plant pathogen battle: A tomato protein"s dual role in defense and susceptibility
Tomatoes, a staple crop worldwide, are increasingly threatened by biotic stressors such as viruses, fungi, and bacteria, with the effects worsening under climate change. These challenges lead to reduced yields and compromised nutritional quality, hig.....»»
Redwood Materials signs deal to recycle BMW’s EV batteries in the US
The automaker will use recycled materials from Redwood in its American-made EVs. Enlarge / BMW is moving to cylindrical cells for its sixth-generation EV powertrain, which debuts in the Neue Klasse. And now it has a recycling par.....»»
Could you find what a lunar crater is made of by shooting it?
Americans are famously fond of their guns. So it should come as no surprise that a team of NASA scientists has devised a way to "shoot" a modified type of sensor into the soil of an otherworldly body and determine what it is made out of. That is prec.....»»
Silencing in action: How cells "repress" genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of "cryptic" genomic regions, including ancient viral sequences......»»
Harmless strain of E. coli bacteria may be able to prevent urinary tract infections
Researchers from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) and the College of Engineering are collaborating on a project that uses harmless strains of E. coli bacteria to disrupt the bacteria responsible for urinary.....»»
Scientists identify 18 bacterial strains to treat antibiotic-resistant gut infections
Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time. Gram-negative bacteria such as Enteroba.....»»
What Is Sickle Cell Disease?
You have around 35 trillion red blood cells moving around your body at all times. Typically they are rounded and flexible. What happens when they aren’t?.....»»
AirPods 4 review: big deal, small package
I’ve been an AirPods user since 2016, and an AirPods Pro user since 2019. In-ear tips are a better fit for my ears, and Active Noise Cancellation and Transparency modes define the modern AirPods experience for me. For some, however, in-ear tips.....»»
Computational tool can pinpoint causal relationships from complex biological data
Researchers have developed a tool that provides new insights into cause-and-effect relationships between cells and how these change over time......»»
Do bacteria age?
Any organism that lives, grows and reproduces must also age. People often think of aging in the physical sense—gray hair, slowed movements and wrinkles—but aging fundamentally occurs on a molecular level, inside of cells......»»
Scientists decipher the energy patterns in our cells
Our cells harness energy for essential functions such as division, wound healing, and our immune response to diseases including cancer. But until now, the mechanics of how that energy affects cell behavior—and how this relates to health outcomes—.....»»