Targeted small molecule alleviates arthritis symptoms in mice
Researchers at the University of Helsinki, together with researchers from the United States, have discovered a small molecule that inhibits the formation in cells of cytokine proteins that promote inflammation. The mechanism is based on the fact that.....»»
Path to precision: Targeted cancer drugs go from table to trials to bedside
What started in a scientist's dining room is now in tissue-agnostic combo trials. Enlarge (credit: Aurich Lawson) In 1972, Janet Rowley sat at her dining room table and cut tiny chromosomes from photographs she had taken.....»»
Hubble images a pair of tiny dwarf galaxies
A pair of new Hubble images show small dwarf galaxies, one of which is thought to be the result of a historical merger......»»
Memo to the Supreme Court: Clean Air Act targeted CO2 as climate pollutant, study says
New paper digs into congressional archives to settle a legal debate. Enlarge (credit: Getty Images | Rudy Sulgan) This article originally appeared on Inside Climate News, a nonprofit, independent news organization that c.....»»
Asus ProArt PX13 review: a uniquely small and powerful laptop
The Asus ProArt PX13 leverages AMD's latest Ryzen AI 9 chipset for excellent creativity performance. Creators will love the excellent portability......»»
Novel system for highly sensitive detection of small molecule pollutants in food and the environment
A research team from the Hefei Institutes of Physical Science of Chinese Academy of Sciences, developed a novel competitive dual-channel color-tone change fluorescent immunochromatographic assay (CFICA)......»»
New compound found to be effective against "flesh-eating" bacteria
Researchers at Washington University School of Medicine in St. Louis have developed a novel compound that effectively clears bacterial infections in mice, including those that can result in rare but potentially fatal "flesh-eating" illnesses. The com.....»»
The iPhone 16 Pro may have a larger battery than we expected
The iPhone 16 Pro may not have as small a battery capacity as we were fearing. A new leak has revealed details about both the 16 Pro and Pro Max......»»
Ancient Antarctic microorganisms are aggressive predators
In Antarctica there is a small lake, called Deep Lake, that is so salty it remains ice-free all year round despite temperatures as low as -20°C in winter. Archaea, a unique type of single-celled microorganism, thrive in this bitterly cold environmen.....»»
Scientists reveal transport mechanism of norepinephrine transporter and binding mode of small molecule and peptide drugs
Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons......»»
Troubling bird flu study suggests human cases are going undetected
A small sample of farm workers is enough to confirm fears about H5N1 outbreak. Enlarge (credit: Tony C. French/Getty) A small study in Texas suggests that human bird flu cases are being missed on dairy farms where the H5.....»»
Penguin wing fossil shows importance of Zealandia in penguin evolution
Three small fossil penguin bones, collected in South Canterbury in 1987, are now shedding new light on how penguin wings have evolved. A new study, published in the Journal of the Royal Society of New Zealand, describes a new species of penguin that.....»»
Peregrine falcons mount a comeback in Yosemite, thanks to rock climbers
Four decades ago, fragile falcon eggs were saved from certain death by Ken Yager and a small team of expert climbers from a nest on Yosemite's El Capitan sheer granite wall, as protective parents dive-bombed from the sky......»»
Best Buy Back to School Sale — Laptops, tablets, TVs, more on sale
Here's what Best Buy has to offer for you this upcoming school year. From small TVs to small appliances, you need this!.....»»
Engineered microbes found to repel mosquitoes
Genetically-engineered human skin bacteria can make mice less attractive to mosquitoes for 11 days. Mosquitoes transmit a host of deadly diseases, including malaria, West Nile, dengue, yellow fever, and Zika. Female mosquitoes on the hunt for a blood.....»»
A Wednesday star takes on a small-town murder mystery in this new YA Netflix series
A Wednesday star takes on a small-town murder mystery in this new YA Netflix series.....»»
Elusive predicted water structure created in the laboratory
Clathrate hydrates are complex water structures that contain foreign guest molecules inside a host water-molecule shell. A predicted clathrate hydrate phase structure has been stably synthesized in the lab and may play an important role in future mat.....»»
Here’s How Long the iOS 16.7.9 Update Takes
Apple’s new iOS 16.7.9 update is a small maintenance release, but it could still take quite a bit of time to install on your iPhone. If you’re moving your iPhone from the latest version of iOS 16 to iOS 16.7.9, you get the shortest list of change.....»»
Fruitful innovation: Transforming watermelon genetics with advanced base editors
The development of new adenine base editors (ABE) and adenine-to-thymine/guanine base editors (AKBE) is transforming watermelon genetic engineering. These innovative tools enable precise A:T-to-G and A:T-to-T base substitutions, allowing for targeted.....»»
Precise genetics: New CRISPR method enables efficient DNA modification
With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This targeted cut allows the D.....»»
Developing new methods for targeted protein degradation
Northwestern Medicine scientists have developed a new, more precise method to target proteins implicated in certain types of cancer, according to a study published in Nature Chemical Biology......»»