Sinhcaf-dependent histone deacetylation essential for primordial germ cell specification
Primordial germ cells (PGCs) are the first germ-cell population established during development. The survival of species is dependent upon PGCs in sexually reproducing organisms because they are the founder cells for the germline......»»
The First Crispr Treatment Is Making Its Way to Patients
It’s been a year since the gene-editing treatment Casgevy was approved for sickle cell disease and a related blood disorder. It’s finally being infused into patients......»»
Picky proteins: Understanding yeast adaptor protein selectivity
The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis......»»
Theoretical model explains the anomalous properties of water in extreme conditions
Water, a molecule essential for life, has unusual properties—known as anomalies—that define its behavior. However, there are still many enigmas about the molecular mechanisms that would explain the anomalies that make the water molecule unique. D.....»»
Squishy microgels in granular biomaterials confine and direct cell behavior
A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State......»»
Deals: M4 MacBook Pro hits all-time low at $125 off, GPS+Cell Apple Watch Series 10 $50 off, Alpine Loops, more
Joining all-time lows on the 42mm and 46mm Apple Watch Series 10 starting from $349, today Amazon has decided to carry the deep discounts over to the GPS+Cell models, including both the aluminum and higher-end titanium variants starting at $449 (the.....»»
Scientists develop a phase-transformable membrane for efficient gas separation
Industrial gas separation, essential for clean energy and environmental protection, demands efficiency and adaptability. Current materials, however, lack the flexibility to selectively separate gases like carbon dioxide (CO2) and hydrogen (H2) while.....»»
Using CRISPR to decipher whether gene variants lead to cancer
In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the genetic material of living organisms. One application is in cell therapy: A patient's immune cells can be specifically reprogramm.....»»
3D leaf edge reconstruction method enhances plant morphology analysis
Leaves, essential for photosynthesis and other physiological functions, exhibit diverse shapes that help plants adapt to their environments. Traditional methods for measuring leaf morphology have relied heavily on 2D imaging, which fails to capture t.....»»
New SMB-friendly subscription tier may be too late to stop VMware migrations
Broadcom acquisition was a "wake-up call" for VMware-dependent SMBs. Broadcom has a new subscription tier for VMware virtualization software that may appease some disgruntled VMw.....»»
Mitochondrial study offers new insights into how our cells process RNA for energy production
Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have made a major discovery in how human cells produce energy. Their study, published in The EMBO Journal, reveals the detailed mechanisms of how mitochondria process.....»»
3 new PS Plus games to play this weekend (November 8-10)
Hot Wheels Unleashed 2 - Turbocharged, Death Note Killer Within, and Ghostwire Tokyo are all PS Plus Essential monthly games that subscribers should check out......»»
Locally optimized urban form can reduce carbon dioxide emissions
Research suggests that urban areas could reduce their carbon dioxide (CO2) emissions by optimizing their urban form. However, the relationship between urban form and emissions is highly context-dependent and generalizations cannot be made......»»
Addigy simplifies compliance for Apple devices with one-click CMMC and DISA STIG benchmarks
For managed service providers (MSPs) and IT administrators working with the Department of Defense or its contractors, staying compliant with cybersecurity rules isn’t just important—it’s essential. Yet, ensuring compliance with standards like t.....»»
The Baseus PicoGo 45W iPhone Charger is a must-have travel essential
If you’re looking for a small and portable charger, then you might want to take a look at the Baseus PicoGo 45W Charger. The post The Baseus PicoGo 45W iPhone Charger is a must-have travel essential appeared first on Phandroid. These day.....»»
Enzyme engineering has the potential to drive more sustainable and efficient drug manufacturing
Researchers have found a new way to use biocatalysis to improve the production of critical raw materials required for essential drugs, making the process quicker, more efficient, and environmentally friendly. Biocatalysis is a process that uses enzym.....»»
Researchers uncover focal adhesions as subcellular signaling hubs in PI3K-AKT pathway
The phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central regulator of various cellular processes including cell growth, proliferation, metabolism, an.....»»
Exploring how microbes in permafrost contribute to nitrous oxide emissions
Ecologist Christina Biasi is exploring the conditions under which tiny organisms contribute to permafrost soils emitting nitrous oxide. Her research could be essential for the development of future climate scenarios......»»
Research highlights biofortification"s role in tackling malnutrition
A series of research papers and a free online data dashboard seek to boost the use of biofortification—an affordable, sustainable and climate-smart way to address global malnutrition by increasing the concentrations of essential nutrients in staple.....»»
Beta cells: New insights into the structure, interactions and neuronal networking of primary cilia
Dysfunctions of the tiny cell processes (primary cilia) of the pancreatic beta cells could be a cause of type 2 diabetes. Little is known about the structure and function of these cilia. An international research team led by DZD researchers from the.....»»
Study highlights microalgae as sustainable ingredients for food and pharmaceutical applications
Microalgae are gaining recognition as sustainable, nutrient-rich sources of bioactive compounds, including proteins, lipids, and carbohydrates, which are essential for various food and health-related applications......»»