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Seeing double: Designing drugs that target "twin" cancer proteins

Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»

Category: topSource:  physorg6 hr. 44 min. ago

Biologists sequence proteins by pulling them through nanopores

A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»

Category: topSource:  theglobeandmailRelated NewsSep 26th, 2024

Researcher develops low-sugar ice cream with smooth texture

Wageningen researcher Qi Wang has developed a new variant of low-sugar ice cream that mimics the texture and melting properties of traditional ice cream. By replacing half of the sugar with broken-down proteins or the sweetener xylitol, she succeeded.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Climate-smart grazing: Study shows how weather mitigates nitrogen runoff

Livestock production is an important component of U.S. agriculture, with global demand for meat and dairy expected to double in the coming decades. This increase will lead to intensified grazing on U.S. grasslands, potentially exacerbating water qual.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Strategies for maximizing recombinant protein production in tobacco plants

Plant molecular farming (PMF) is a modern, sophisticated technology that utilizes plants' biosynthetic machinery to synthesize a plethora of recombinant proteins, including industrial and therapeutic enzymes. It has several advantages over traditiona.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Naked mole-rat found to have lost infection-resistant proteins

Scientists have found that the naked mole-rat—an underground rodent that lives up to 40 years—has lost a number of CD1 functional genes. The CD1 gene family in mammals is responsible for protein synthesis that protects the body against infectious.....»»

Category: topSource:  informationweekRelated NewsSep 25th, 2024

Better together: Gut microbiome communities found to have enhanced resilience to drugs

Many human medications can directly inhibit the growth and alter the function of the bacteria that constitute our gut microbiome. EMBL Heidelberg researchers have now discovered that this effect is reduced when bacteria form communities......»»

Category: topSource:  physorgRelated NewsSep 24th, 2024

Bird flu is spreading rapidly in California; infected herds double over weekend

The state reported its first infected herds on August 30. Enlarge / Cows being milked in Wisconsin on May 8, 2024. (credit: Getty | Matthew Ludak) The H5N1 bird flu appears to be stampeding through dairy farms in Califo.....»»

Category: topSource:  arstechnicaRelated NewsSep 23rd, 2024

Chemists discover new ways in which single-celled organisms organize their DNA

It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden Ph.D. candidate Samuel Schwab has found that the histones in these organisms are much more diverse.....»»

Category: topSource:  physorgRelated NewsSep 23rd, 2024

From chaos to order: Proteins can re-structure themselves to create important substances

The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»

Category: topSource:  physorgRelated NewsSep 23rd, 2024

Proof-of-concept study uses X-rays to target mock-up asteroids in a vacuum

An X-ray pulse may be able to vaporize the surface of an asteroid and change its trajectory, according to a proof-of-concept paper published in Nature Physics. A laboratory experiment that mimics the deflection of an asteroid model using this techniq.....»»

Category: topSource:  physorgRelated NewsSep 23rd, 2024

Elon Musk shares new target date for Starship voyage to Mars

But it's worth noting that the SpaceX CEO's forecasts often slip......»»

Category: topSource:  digitaltrendsRelated NewsSep 23rd, 2024

Boca double homicide: Boynton man arrested in Georgia after shooting at beachfront hotel

Boca double homicide: Boynton man arrested in Georgia after shooting at beachfront hotel.....»»

Category: topSource:  theglobeandmailRelated NewsSep 22nd, 2024

New method developed to relocate misplaced proteins in cells

Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»

Category: topSource:  pcmagRelated NewsSep 21st, 2024

Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?

Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?.....»»

Category: topSource:  informationweekRelated NewsSep 21st, 2024

Austin airport proposes new plan to nearly double in size in largest expansion ever

Austin airport proposes new plan to nearly double in size in largest expansion ever.....»»

Category: gadgetSource:  yahooRelated NewsSep 21st, 2024

How much auto demand will the Fed"s half-point rate cut produce?

The Federal Reserve cut its benchmark rate target 0.5 percentage points on Sept. 18, which could reduce the market interest rates that Cox Automotive polling indicates are dealerships' No. 1 challenge......»»

Category: topSource:  autonewsRelated NewsSep 21st, 2024

Copper-based nanocapsules shown to enhance radiotherapy effectiveness

In a study published in Nature Nanotechnology, researchers discovered that cuproptosis may serve as a new target for radiosensitization in re-irradiation......»»

Category: topSource:  physorgRelated NewsSep 20th, 2024

Study shows cholesterol enhances exosome-mediated RNA drug delivery

RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»

Category: topSource:  physorgRelated NewsSep 20th, 2024

Double-edged STING: A new pathway involved in aging

A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»

Category: topSource:  physorgRelated NewsSep 20th, 2024

Exploring the interplay between phosphate signaling and jasmonate pathways in tea plants

Catechins, the key active components in tea, are known for their protective effects against conditions like diabetes, cancer, and cardiovascular diseases. However, their biosynthesis is highly sensitive to environmental factors, particularly phosphat.....»»

Category: topSource:  physorgRelated NewsSep 20th, 2024