SARS-CoV-2: Neutralization of BA.1 and BA.2 by therapeutic monoclonal antibodies
Scientists studied the sensitivity of Omicron BA.1 and BA.2 to nine monoclonal antibodies, some of which are used in pre-exposure prophylaxis in immunocompromised individuals. The scientists showed a loss of neutralizing activity against BA.1 and BA......»»
Novel nanoparticles can trap and neutralize large amounts of SARS-CoV-2
Researchers from the IBB-UAB have developed a new class of nanostructures capable of trapping and neutralizing large quantities of the SARS-CoV-2 virus particles, both in liquid solutions and on the surface of materials......»»
Experiments demonstrate precise delivery of nanoparticles to lung via caveolae pumping system
In recent years, bio-medical engineers have been developing promising techniques that could help diagnose diseases or precisely target specific regions inside the human body. Among these promising therapeutic strategies are methods that rely on the u.....»»
Novel self-cleaning electrode developed for alkaline-earth metal peroxide synthesis
Metal peroxide (MO2, M=Ca, Sr, Ba) is an alternative to hydrogen peroxide (H2O2). It has excellent oxidative properties, superior chemical stability, high purity, and is easy to store and transport. It has been widely used in wastewater treatment and.....»»
Advancing drug delivery: New framework links lipid nanoparticle structure to immune response
A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune response. It can help scientists and engineers expand the use of RNA medicines beyond vaccines to other therapeutic applications.....»»
Russian officials buy four times more iPhones after ban
Despite an official ban on Russian government workers using the iPhone, an unreliable report says that sales have risen dramatically.Moscow at night — image credit: Evgenit/PixabayIt was in 2023 that Russia's Federal Security Service (FSB) tried ba.....»»
Nanoparticle technology demonstrates selective destruction of leukemia cancer cells
A research team, affiliated with UNIST has developed nanoparticles that effectively treat acute myeloid leukemia (AML), offering the potential to reduce side effects while enhancing therapeutic efficacy by selectively targeting and eliminating leukem.....»»
Putting out a brain on fire: Researchers map how antibodies bind in rare autoimmune disorder
Imagine you wake up in a hospital without a single memory of the last month. Doctors say you had a series of violent episodes and paranoid delusions. You'd become convinced you were suffering from bipolar disorder. Then, after a special test, a neuro.....»»
Novel nanoparticle therapy targets fat absorption to combat obesity
Researchers have unveiled a novel approach to tackle obesity by targeting fat absorption in the small intestine. The cutting-edge nanoparticle system, engineered to deliver therapeutic molecules directly to the digestive tract, has shown significant.....»»
Scientists discover novel series of SARS-CoV-2 Mpro inhibitors for potential new COVID-19 treatments
New research from The Wistar Institute's Salvino lab, led by professor Joseph Salvino, Ph.D., has identified a novel series of SARS-CoV-2 Mpro inhibitors that may lead to potential new COVID-19 treatments that—according to preclinical testing—eff.....»»
Researchers design a drug capable of acting simultaneously against three different therapeutic targets
A study led by researchers of the Institute of Biomedicine of the University of Barcelona (IBUB) has developed a new pharmacological tool capable of simultaneously administering three oligonucleotide-based drugs, each acting against a different thera.....»»
AI and quantum mechanics team up to accelerate drug discovery
Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects. That requirement for a meticulous fit means the creation of new dr.....»»
Deals: Silver Apple Watch Series 10 all-time low, iPad Smart Folio, up to 30% off leather and metal bands, and more
Joining ongoing all-time low prices on the new black Titanium Apple Watch Ultra 2, today’s deals are headlined by the best offer yet on the 46mm Apple Watch Series 10 with the silver aluminum case alongside a host of brand new metal and leather ba.....»»
3D structure of key protein could advance development of hormone-free male contraceptive pill
Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»
Strategies for maximizing recombinant protein production in tobacco plants
Plant molecular farming (PMF) is a modern, sophisticated technology that utilizes plants' biosynthetic machinery to synthesize a plethora of recombinant proteins, including industrial and therapeutic enzymes. It has several advantages over traditiona.....»»
Genetic tracing at the Huanan Seafood market further supports COVID animal origins
A new international collaborative study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of meta.....»»
Researchers develop new method for delivering RNA and drugs into cells
Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA and potent drugs directly into cells, potentially leading to a more effective treatment of diseases......»»
Virtual laboratory allows scientists to simulate specific decreases in gene activity
Imagine you're looking at millions upon millions of mysterious genetic mutations. With CRISPR gene-editing technology, a select few of these mutations might have therapeutic potential. However, proving it would mean many thousands of hours of lab wor.....»»
Solving the side effect problem of siRNA drugs for genetic disease treatment
Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often silence genes other than the target ones, causing side eff.....»»
Scientists develop new chemical tool for infection research
Researchers from Würzburg and Berlin present a new molecule for visualizing the sphingomyelin metabolism. This offers prospects for innovative therapeutic approaches in infection research. The work is published in the journal Nature Communications......»»
Researchers investigate cell-free DNA as early sepsis marker in foals
It's hard to be a horse. It's especially hard to be a newborn foal, dropped into a world of microbes and bacteria with your sole initial defense against devastating infections being the antibodies you get from your mother's milk, or colostrum. Resear.....»»