RNA modification: Mechanisms and therapeutic targets
RNA modifications are dynamic and reversible chemical modifications on substrate RNA that regulate mRNA stability, translation, and localization. This review is designed by Dr. Junhong Han and written by his postdoctoral researcher Dr. Lei Qiu and P.....»»
Despite Nissan"s missed targets, CEO Makoto Uchida gives himself a B, shifts to volume mode
CEO Makoto Uchida says Nissan has strengthened its business significantly over the course of his first midterm business plan but still must "work harder" to boost global volume. Here's a score card......»»
Team develops an epigenome editing toolkit to dissect the mechanisms of gene regulation
Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription factors, DNA regulatory regions, and epigenetic mo.....»»
The 7 Habits of Highly Effective… Pirates?
In an effort to tackle online piracy, Lithuania has been issuing €140 fines to online pirates, catching several dozen people in the first few months. These early targets were mostly movie pirates on private trackers. However, a recent announcement.....»»
Study shows female gamers only label half of sexual harassment incidents they experience as such
A new study from the Kinsey Institute reveals that only 50.5% of women who were targets of sexual harassment during online gaming identified qualifying incidents as such. This figure dropped further to only 42.2% for women who witnessed sexual harass.....»»
Study reveals differences in DNA folding between neurons and other brain cells, links them to cell functions
Researchers from Skoltech and their colleagues have investigated nerve cell regulation. Mounting knowledge of regulation mechanisms could enable a better understanding of how the healthy brain operates and what goes wrong in developmental and oncolog.....»»
Fruit fly model identifies key regulators behind organ development
A new computational model simulating fruit fly wing development has enabled researchers to identify previously hidden mechanisms behind organ generation......»»
Study reveals rockburst processes, characteristics and triggering mechanisms
Field observations have revealed that highly stressed D-shape tunnels experience sidewall rockburst triggered by impact loads stemming from rock blasting or other mining-related dynamic disturbances......»»
Attosecond core-level spectroscopy reveals real-time molecular dynamics
Chemical reactions are complex mechanisms. Many different dynamic processes are involved, affecting both the electrons and the nucleus of the present atoms. Very often, the strongly coupled electron and nuclear dynamics induce radiation-less relaxati.....»»
Fluidic telescope (FLUTE): Enabling the next generation of large space observatories
The future of space-based UV/optical/IR astronomy requires ever larger telescopes. The highest priority astrophysics targets, including Earth-like exoplanets, first generation stars, and early galaxies, are all extremely faint, which presents an ongo.....»»
Developing a tech platform for fast, robust series production of nanoparticles
Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are neede.....»»
New SOHO router malware aims for cloud accounts, internal company resources
Cuttlefish, a new malware family that targets enterprise-grade small office/home office (SOHO) routers, is used by criminals to steal account credentials / secrets for AWS, CloudFlare, Docker, BitBucket, Alibaba Cloud and other cloud-based services......»»
Friends with health benefits: How a friend might make pursuing goals more attainable
Weekly targets, annual resolutions, five-year plans—all of them so troublingly elusive. With best intentions, most of us fail to stick with the goals we set......»»
Scientists say voluntary corporate emissions targets not enough to create real climate action
Companies' emissions reduction targets should not be the sole measure of corporate climate ambition, according to a new perspective paper......»»
Anatomy IT’s new Security Suite targets healthcare cybersecurity threats, improves incident response
Anatomy IT has announced the launch of an expanded end-to-end cybersecurity product suite designed to safeguard healthcare delivery organizations from evolving and growing IT system threats. A record 133 million individuals were affected by healthcar.....»»
How evolution has optimized the magnetic sensor in birds
Migratory birds are able to navigate and orientate with astonishing accuracy using various mechanisms, including a magnetic compass. A team led by biologists Dr. Corinna Langebrake and Prof. Dr. Miriam Liedvogel from the University of Oldenburg and t.....»»
Hackers are using developing countries for ransomware practice
Businesses in Africa, Asia, and South America hit before moving on to Western targets. Enlarge (credit: Getty Images) Cyber attackers are experimenting with their latest ransomware on businesses in Africa, Asia, and Sout.....»»
Researchers unveil PI3K enzyme"s dual accelerator and brake mechanisms
A group of researchers have expanded conventional knowledge on a critical enzyme that controls cell migration. In a publication in the journal Nature Communications, they reported that phosphoinositide 3-kinase (PI3K) not only acts as an accelerator.....»»
Hackers are carrying out ransomware experiments in developing countries
Businesses in Africa, Asia, and South America hit before moving on to western targets. Enlarge (credit: Getty Images) Cyber attackers are experimenting with their latest ransomware on businesses in Africa, Asia and South.....»»
CEO Mary Barra"s pay declined 3.9% to $27.8 million as GM missed stock targets
After eight consecutive years as the highest-paid Detroit 3 CEO, Barra's compensation trailed the $39 million Stellantis shareholders approved for Carlos Tavares......»»
Researchers report on mechanisms of gene regulatory divergence between species
Closely related animal species can look physically different, but you might be surprised to learn that those differences can result not only from DNA sequence changes that alter proteins' structure or function, but also because changes in the DNA aff.....»»