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Review: PROTACs targeting epigenetic proteins

The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications of DNA bases. These.....»»

Category: topSource:  physorgDec 6th, 2023

Neva review: gorgeous 2D platformer still has room to grow

Neva packs a lot of emotion and splendor into a small, and at times overly light, 2D platformer......»»

Category: topSource:  digitaltrendsRelated NewsOct 14th, 2024

Meta Quest 3S review: the perfect introduction to VR gaming

I reviewed Meta's Quest 3S, a budget VR headset with mixed reality and AI, to test its quality and value as an upgrade or a first headset......»»

Category: topSource:  digitaltrendsRelated NewsOct 14th, 2024

Bowers & Wilkins Pi8 In-Ear True Wireless Earbuds review: what we’ve been waiting for

Bowers & Wilkins is known for creating exceptional audio experiences, and its new Pi8 earbuds continue that legacy......»»

Category: topSource:  digitaltrendsRelated NewsOct 14th, 2024

Novel nanoparticle therapy targets fat absorption to combat obesity

Researchers have unveiled a novel approach to tackle obesity by targeting fat absorption in the small intestine. The cutting-edge nanoparticle system, engineered to deliver therapeutic molecules directly to the digestive tract, has shown significant.....»»

Category: topSource:  theglobeandmailRelated NewsOct 13th, 2024

Sony InZone M10S review: the brightest OLED monitor I’ve reviewed

The Sony InZone M10S is the first OLED monitor Sony has released, and it just so happens to be the brightest, too. However, a lagging warranty hold it back......»»

Category: topSource:  digitaltrendsRelated NewsOct 13th, 2024

Week in review: Microsoft fixes two exploited zero-days, SOC teams are losing trust in security tools

Here’s an overview of some of last week’s most interesting news, articles, interviews and videos: Microsoft patches two zero-days exploited in the wild (CVE-2024-43573, CVE-2024-43572) For October 2024 Patch Tuesday, Microsoft has released fixes.....»»

Category: securitySource:  netsecurityRelated NewsOct 13th, 2024

Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry

The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology's biggest challenges: predicting the 3D shape of proteins and designing them from scratch......»»

Category: topSource:  physorgRelated NewsOct 12th, 2024

Saturday Night review: A Saturday Night Live origin story that plays it too safe

Jason Reitman assembles a giant, game ensemble for Saturday Night, a SNL origin story that's a little too reverent and tidy......»»

Category: topSource:  digitaltrendsRelated NewsOct 12th, 2024

Targeting "undruggable" diseases: Researchers reveal new levels of detail in targeted protein degradation

Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called protein degraders which can be deployed to combat what have previously been regarded as "undruggable" diseases, including cancers and ne.....»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

Study proposes that proteins can compartmentalize and form droplets inside cells

In physics, a system composed of two substances can be modeled in accordance with classical mixture theory, which considers the fraction corresponding to each constituent and the interactions among constituents. Examples include the coexistence of hi.....»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

Mullvad VPN review: total anonymity for an affordable price

I reviewed Mullvad, a unique VPN with consistently low prices to find out it it's speed, features, and reliability are worth the cost......»»

Category: topSource:  digitaltrendsRelated NewsOct 11th, 2024

Polestar CEO Michael Lohscheller starts review after deliveries disappoint

New boss Michael Lohscheller said the Swedish EV maker will develop its commercial capabilities so it can go “from showing to actively selling cars.”.....»»

Category: topSource:  autonewsRelated NewsOct 11th, 2024

High-resolution structural data shows how a supercomplex links mRNA translation and decay

Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena Conti and her team at the Max Planck Institute of Biochemistry in Martinsried near Munich have now been able to show that the.....»»

Category: topSource:  informationweekRelated NewsOct 10th, 2024

Targeting "selfish" bacteria could optimize inhibitors that fight antibiotic resistance

As strains of pathogens resistant to frontline antibiotics become more common worldwide, clinicians are more often turning to combination treatments that degrade this resistance as a first treatment option......»»

Category: topSource:  informationweekRelated NewsOct 10th, 2024

Tomb Raider: The Legend of Lara Croft review: a surprisingly good video game spinoff

Netflix's Tomb Raider: The Legend of Lara Croft is an entertaining, visually striking series that actually does right by its iconic protagonist......»»

Category: topSource:  digitaltrendsRelated NewsOct 10th, 2024

Soundcore Select 4 Go review: This speaker might be the perfect $25 gift

You shouldn't expect much from a $25 Bluetooth speaker, and yet the Soundcore Select 4 Go is surprisingly great......»»

Category: topSource:  digitaltrendsRelated NewsOct 10th, 2024

Researchers discover new isotope plutonium-227

A research team led by researchers at the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS) has synthesized a new plutonium isotope, plutonium-227. Their study is published in Physical Review C......»»

Category: topSource:  physorgRelated NewsOct 10th, 2024

RingConn Gen 2 review: the money-saving smart ring to buy

The RingConn Gen 2 is cheaper than the other smart rings and doesn't have a subscription, and our review tells you if it's all too good to be true......»»

Category: topSource:  digitaltrendsRelated NewsOct 10th, 2024

Nobel chemistry winner sees engineered proteins solving tough problems

Whether it's battling tumors or breaking down plastic, American scientist David Baker, co-recipient of this year's Nobel Prize in Chemistry, has an answer: engineering proteins that don't naturally exist—a concept once dismissed as "crazy.".....»»

Category: topSource:  physorgRelated NewsOct 10th, 2024

Review of English-language textbooks from 34 countries reveals persistent pattern of stereotypical gender roles

Gender biases around male and female roles and under-representation of female characters appeared in textbooks from around the world, with male-coded words appearing twice as often as female-coded words on average, according to a study published Octo.....»»

Category: topSource:  theglobeandmailRelated NewsOct 9th, 2024