Review: PROTACs targeting epigenetic proteins
The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications of DNA bases. These.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Discovery of a hidden epigenetic clock in mitochondria reveals a "lifespan limit line"
Building on their work on epigenetics of aging and transposable elements, researchers Dr. Ádám Sturm and Dr. Tibor Vellai from Eötvös Loránd University have made another advance in understanding the molecular mechanisms of aging. Their latest st.....»»
3D shapes of viral proteins point to previously unknown roles
Viruses are tricky to keep up with. They evolve quickly and regularly develop new proteins that help them infect their hosts. These rapid shifts mean that researchers are still trying to understand a multitude of viral proteins and precisely how they.....»»
Tomato ripening study highlights cell wall component interactions
Tomato fruit ripening involves intricate biochemical and structural changes, particularly within the cell wall, which are vital for the fruit's final texture and quality. These changes include modifications in polysaccharides and proteins, but the sp.....»»
Google Pixel 9 Pro review: the iPhone of Android
The Pixel 9 Pro is one of the absolute best Android phones of the year. Our full review explains why it should be your next phone......»»
Review: Synology BeeStation offers a local network alternative to iCloud and Dropbox cloud storage
Best known for their network attached solutions (like my beloved DS920+), Synology have recently launched a new product in their lineup, called the . The BeeStation aims to simplify the idea of a home NAS, offering a local network backup option as.....»»
Nest Smart Learning Thermostat, Sonos app issues, & Wi-Fi issues on HomeKit Insider
On this episode of the HomeKit Insider Podcast, we review the brand-new Nest Learning Thermostat fourth-generation as well as answer a few listener questions.HomeKit Insider PodcastThis week in the news the Sonos CEO said while they were hopeful they.....»»
New genetic sensor for DNA methylation discovered
DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and is a major way that DNA is epigenetically marked. Epigenetic modifications can act as on–off switches to regulate gene expression and hel.....»»
Week in review: PostgreSQL databases under attack, new Chrome zero-day actively exploited
Here’s an overview of some of last week’s most interesting news, articles, interviews and videos: PostgreSQL databases under attack Poorly protected PostgreSQL databases running on Linux machines are being compromised by cryptojacking attackers......»»
Aventon Ramblas eMTB e-bike review: the trails are waiting
Even if you're an experienced mountain bike rider, you should check out what Aventon includes in its first eMTB......»»
The Crow review: a goth remake that never really comes alive
Rupert Sanders' remake of The Crow, starring Bill Skarsgård and FKA Twigs, is an undercooked, but watchable blend of ideas without much thought put into them......»»
HP Color LaserJet Pro 3201dw review: small, fast and awkward
Find out the pros and cons of HP's new Color LaserJet Pro 3201dw in this hands-on review that uncovers some issues and suggests alternatives......»»
The Killer review: a fun, forgettable remake of an action genre classic
John Woo's The Killer, a remake of his own 1989 action movie classic, is better than it has any right to be......»»
Concord review: PS5 shooter has potential, but it’s lost in space for now
Concord has all the right pieces that make for a fun hero shooter, but it can't quite put them together......»»
Google Pixel 9 review: better than ever
The Google Pixel 9 comes with Gemini AI, but guess what? AI isn't the reason this is a good phone, as we explain in our in-depth review......»»
Rode Wireless Pro review: Impressive features, superb audio quality
Rode's wireless microphone systems have been the choice of creators for years. The new Rode Wireless Pro system has enhanced features, and radically improves sound quality, connectivity, and user experience.The Rode Wireless Pro microphone system is.....»»
After months of mulling, NASA will decide on Starliner return this weekend
"The agency flight readiness review is where any formal dissents are presented and reconciled." Enlarge / A high-resolution commercial Earth-imaging satellite owned by Maxar captured this view of the International Space Station o.....»»
Research reveals many laws targeting homelessness are ineffective
A University of Texas at Arlington professor recently published a study that found no correlation between laws criminalizing homeless activities and a long-term reduction of homelessness......»»
Keychron Q15 Max review: High-quality and quirky mechanical keyboard
The Keychron Q15 Max is a premium keyboard option for those who are on board with ortholinear setups, or want to give it a try.Keychron Q15 Max reviewAn ortholinear keyboard has a non-staggered layout, where keys are aligned in a grid format. They of.....»»
Google Pixel 9 Pro XL review: a huge success
The Google Pixel 9 Pro XL is a big and expensive smartphone. It's also one of the best I've used this year. Let me explain why in my full review......»»