Repurposed protease controls important signaling molecule-activating protein
Efficient communication between cells is vital for many biological processes, such as recruiting immune cells to combat disease. The rapid release of at least 80 signaling molecules, including tumor necrosis factor and epidermal growth factor, is con.....»»
Glowing proteins enable real-time, 3-D study of essential enzymes
Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival. Malfunction o.....»»
Calcium transport protein in bacteria offers insights for drug development and food safety
Researchers at Umeå University have revealed details on how bacteria use calcium to regulate vital processes in a way that differs from human cells. This breakthrough is significant in the fight against antibiotic resistance and for increasing safet.....»»
Physicists uncover behavior in quantum superconductors that provides a new level of control
A new study has uncovered important behavior in the flow of electric current through quantum superconductors, potentially advancing the development of future technologies like quantum computing......»»
Protein USP50 identified as key in DNA replication balance
A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study......»»
Expansion in situ genome sequencing innovation makes hidden DNA-protein interactions visible
Harvard scientists have unveiled a new technique called expansion in situ genome sequencing (ExIGS) that combines existing in situ genome sequencing (IGS) with expansion microscopy (ExM). The innovation allowed researchers to link nucleus abnormaliti.....»»
In Denmark, 50 well-preserved Viking Age skeletons have been unearthed, a rare discovery
In a village in central Denmark, archaeologists made a landmark discovery that could hold important clues to the Viking era: a burial ground, containing some 50 "exceptionally well-preserved" skeletons......»»
Compound drought–heat wave events under-recognized in global soils, finds study
Soil is essential for life and plays a crucial role in the Earth's ecosystem, providing support for plant roots and hosting countless microorganisms. In a warming world, it is important to understand how soil hydrothermal conditions, particularly the.....»»
Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry
The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology's biggest challenges: predicting the 3D shape of proteins and designing them from scratch......»»
Targeting "undruggable" diseases: Researchers reveal new levels of detail in targeted protein degradation
Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called protein degraders which can be deployed to combat what have previously been regarded as "undruggable" diseases, including cancers and ne.....»»
Plant stem cells: Understanding the biological mechanism of growth control
Researchers from the University of Freiburg have identified the HAN molecule as an important regulator that controls plant growth in conjunction with WOX5. Understanding this mechanism is relevant for breeding more resilient or higher-yielding crops......»»
Oxidative stress: How protein recycling protects against cell death
Researchers at LMU University Hospital have discovered a new molecular switch that protects against cell death......»»
Scientists discover how innate immunity envelops bacteria
The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now......»»
Up in smoke: DIY tech to combat wildfires
As wildfires become a more frequent and dangerous part of life, especially in the Pacific Northwest, finding solutions that everyone can use is more important than ever. By June 2024, the Pacific Northwest had already seen more trees burn than in all.....»»
Ubuntu 24.10 Oracular Oriole brings tighter security controls
Canonical released Ubuntu 24.10 Oracular Oriole, which brings notable advancements, including an updated kernel, new toolchains, and the GNOME 47 desktop environment, along with significant enhancements in software security. “Oracular Oriole sets a.....»»
In a rare disclosure, the Pentagon provides an update on the X-37B spaceplane
"This first of a kind maneuver from the X-37B is an incredibly important milestone." After more than nine months in an unusual, highly elliptical orbit, the US military's X-37B sp.....»»
The US military’s X-37B spaceplane is preparing for a “novel space maneuver”
"This first of a kind maneuver from the X-37B is an incredibly important milestone." After more than nine months in an unusual, highly elliptical orbit, the US military's X-37B sp.....»»
Signaling pathway discovery could lead to faster, more reliable human stem cell differentiation
A recent discovery has found a possible avenue to improve human health by better understanding how to engineer human stem cell differentiation......»»
Advanced model predicts gene architecture via nucleosome position
DNA—the molecule that carries the genetic information of all living organisms—is packaged within cells in a complex manner that allows it to function efficiently. Nucleosomes facilitate DNA compaction and also play a crucial role in regulating ge.....»»
AI-driven approach challenges traditional views on protein structure
In a recently published article in Nature Communications,, a team offers an AI-driven approach to explore structural similarities and relationships across the protein universe. The team includes members from the University of Virginia—including Phi.....»»
Poverty-level wages pose urgent problem for US childcare, study finds
A new report from the Center for the Study of Child Care Employment (CSCCE) at UC Berkeley finds that child care workers in every state struggle with poverty-level wages, even as they nurture and educate our children in the most important years of de.....»»