Protecting the genome from transposon activation
Transposons are foreign DNA elements capable of random insertion into the genome, an event that can be very dangerous for a cell. Their activity must be silenced to maintain genomic integrity, which is primarily achieved by H3K9me3-mediated repressio.....»»
Organic chemists develop new catalyst to selectively activate carbon-hydrogen bonds
Substituted aromatics are among the most important building blocks for organic compounds such as drugs, crop-protecting agents, and many materials. The function of the molecules is determined by the spatial arrangement of the different building block.....»»
Power of cancer drugs may see boost by targeting newly identified pathway
Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome—a cell's complete set of DNA—is most vulnerable while it is being duplicated before a cell divides. Cancer cells constantly are di.....»»
Study reveals dynamics of DNA ligation during genome replication
Unconnected strands of DNA must be sealed together during genome replication and repair, and a new KAUST-led investigation shows how the fastening enzyme involved gets the job done......»»
Protecting Amazon a tough task, says Brazil"s environment minister
Brazil's environment minister Marina Silva knows she has her work cut out to protect the Amazon, the world's largest rainforest that is shared among nine countries......»»
Right-to-repair advocate urges Apple to let resellers bypass security protocols
One independent MacBook reseller and right-to-repair advocate has scavenged Macs from a facility that destroys computers for security reasons, and wants Apple to let him disable iCloud Activation Locks.2020 M1 MacBooks are making their way to recycli.....»»
How do you vaccinate a honeybee? Six questions answered about a new tool for protecting pollinators
Honeybees, which pollinate one-third of the crops Americans eat, face many threats, including infectious diseases. On Jan. 4, 2023, a Georgia biotechnology company called Dalan Animal Health announced that it had received a conditional license from t.....»»
World-first computational reconstruction of a virus in its biological entirety
An Aston University researcher has created the first ever computer reconstruction of a virus, including its complete native genome......»»
Protecting and regenerating tropical mangroves
Mangroves were once seen as inhospitable malarial swamps and were among the fastest disappearing habitats in the world. Now, with input from Bangor University, one community project in Kenya is working to restore mangroves in a project which benefits.....»»
Critical impacts of interfacial water on C-H activation in photocatalytic methane conversion
Non-thermal activation and utilization of methane, the main component of natural gas and a ubiquitous natural carbon resource, are among the global challenges for achieving sustainable society. However, incomplete knowledge on microscopic mechanisms.....»»
From octopus to elephant: A molecular zoo of epigenetics
Our genes are encoded in the DNA sequence of the genome, which is highly similar across the diverse cell types of our body. Yet, each cell can only access those genes that are in an epigenetically permissive state. The epigenome thus provides a form.....»»
Modified CRISPR-based enzymes improve the prospect of inserting entire genes into the genome
Many genetic diseases are caused by diverse mutations spread across an entire gene, and designing genome editing approaches for each patient's mutation would be impractical and costly......»»
Ibase new plant to boost capacity significantly
Taiwan-based industrial PC (IPC) maker Ibase Technology hosted an opening ceremony for its new factory in Taoyuan, Taiwan on January 12 and the company's capacity is expected to rise 250% with the activation of the new facility, according to the comp.....»»
Evolution of uniquely human DNA was a balancing act, study concludes
Humans and chimpanzees differ in only one percent of their DNA. Human accelerated regions (HARs) are parts of the genome with an unexpected amount of these differences. HARs were stable in mammals for millennia but quickly changed in early humans. Sc.....»»
Protecting biocatalysts from oxygen
Certain enzymes from bacteria and algae can produce molecular hydrogen from protons and electrons—an energy carrier on which many hopes are riding. All they need for this purpose is light energy. The major obstacle to their use is that they are des.....»»
A fifth of passwords used by federal agency cracked in security audit
89 percent of the department's high-value assets had easy-to-crack passcodes. Enlarge (credit: Getty Images) More than a fifth of the passwords protecting network accounts at the US Department of the Interior—including.....»»
Taiwan "Chips Act" is not all about chips, it"s about innovation
The so-called "Taiwan version of Chips Act" was passed in the Legislative Yuan on January 7, but the amended statutes are not all about chips, nor was it only for "protecting TSMC's processing technologies", and will only be effective until December.....»»
Researchers reveal how geminiviruses cause devastating disease in worldwide crops
Geminiviruses are a group of single-stranded circular plant DNA viruses that cause devastating diseases in many economically important crops including tomato, tobacco, cotton, corn, wheat, beans, and cassava worldwide. Due to their small genome size.....»»
Breakthroughs made as scientists sequence the genomes of endangered sharks
The first chromosome level genome sequences for great hammerhead and shortfin mako sharks have shown that both species have experienced major population declines over a 250,000-year history. Low genetic diversity and signs of inbreeding are concernin.....»»
Breakthrough in plant breeding: Grafting and mobile CRISPR for genome editing in plants
A ground-breaking twist to the CRISPR tool—aka "genetic scissors"—is being put to use to edit plant genomes by scientists from the Max Planck Institute of Molecular Plant Physiology, signaling a methodology change. The discovery, recently publish.....»»
New method precisely locates gene activity and proteins across tissues
A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center......»»