Possible novel migraine therapy
By discovering a potential new cellular mechanism for migraines, researchers may have also found a new way to treat chronic migraine......»»
Researchers develop 3D printed model for targeted antibiotic therapy against follicular infections
Hair follicle infections are often difficult to treat because bacteria settle in the gap between hair and skin, where it is difficult for active substances to reach them......»»
Researchers develop library for RNA-based therapeutic approaches with polymer nanoparticles
RNA therapy with polymer nanoparticles is considered a promising approach for the treatment of various illnesses. It involves the use of polymers as "nanocarriers" to transport RNA drugs precisely to the correct target cells. Manufacturing such polym.....»»
Genetic cloaking of healthy cells opens door to universal blood cancer therapy
Blood stem cells are being engineered to protect them from lethal therapies. Enlarge (credit: Aurich Lawson) Know your enemy, know yourself. It's a centuries-old strategy. But even in the present-day war against cancer,.....»»
FDA’s review of MDMA for PTSD highlights study bias and safety concerns
FDA advisors will meet June 4 to discuss and vote on the therapy's effectiveness. Enlarge / MDMA is now in the FDA's hands. (credit: Getty | PYMCA/Avalon) The safety and efficacy data on the use of MDMA (aka ecstasy) for.....»»
New modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues a.....»»
Personalized phage therapy heals resistant wounds in Siamese cat
A new study has shown an advance in the treatment of antibiotic-resistant infections in animals. The research, focusing on a 5-year-old Siamese cat Squeaks with a multidrug-resistant Pseudomonas aeruginosa infection post-arthrodesis surgery, marks th.....»»
Study reveals cuddled cows who work as therapy animals show a strong preference for women compared to men
A new study, titled "Cow Cuddling: Cognitive Considerations in Bovine-Assisted Therapy" published in the Human-Animal Interactions journal, reveals that cows who are cuddled as therapy animals showed a strong preference for interactions with women wh.....»»
Lipid nanoparticle-mRNA regimen reverses inflammation and aids recovery from diabetic wounds in mice
Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown t.....»»
New method unravels the mystery of slow electrons
Slow electrons are used in cancer therapy as well as in microelectronics. It is very hard to observe how they behave in solids. But scientists at TU Wien have made this possible......»»
More children gain hearing as gene therapy for profound deafness advances
The therapy treats a rare type of deafness, but experts hope it's a "jumping point." Enlarge / Opal Sandy (center), who was born completely deaf because of a rare genetic condition, can now hear unaided for the first time after r.....»»
Researchers develop nanotechnology for creating wafer-scale nanoparticle monolayers in seconds
Nanoscale materials present us with astonishing chemical and physical properties that help materialize applications such as single molecular sensing and minimally invasive photothermal therapy—which were once just theories—into reality......»»
Nanoparticle researchers develop microfluidic platform for better delivery of gene therapy for lung disease
Drug delivery researchers at Oregon State University have developed a device with the potential to improve gene therapy for patients with inherited lung diseases such as cystic fibrosis......»»
Novel triple drug combination effective against antibiotic-resistant bacteria
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The study, "The Triple Combination of Meropenem, Avi.....»»
Antimicrobial peptide from cows shows potential for treating hypervirulent bacteria
University of Central Florida College of Medicine researcher Renee Fleeman is on a mission to kill drug-resistant bacteria, and her latest study has identified a therapy that can penetrate the slime that such infections use to protect themselves from.....»»
Behavioral therapy against aging: Researchers study the effect of therapies on older dogs
It is well known that getting plenty of exercise and mental training are important for a long and healthy life. But which is more effective? Do the tasks develop abilities that go beyond them?.....»»
Lifesaving gene therapy for kids is world’s priciest drug at $4.25M
It's unclear if government and private insurance plans can cover the costs. Enlarge / A mother with her twin 6-year-old boys who have metachromatic leukodystrophy, a genetic disease that leaves them unable to move. Photo taken on.....»»
Advances and applications of nanoparticles in cancer therapy
The research team of Prof. Changyang Gong from the Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University has published a new review showing that rapid growth in nanoparticles as delive.....»»
Research seeks to develop mRNA lipid nanoparticles for next-generation oral cancer tumor suppressor therapy
A study aiming to develop a lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of t.....»»
In vivo production of CAR-T cells using virus-mimetic fusogenic nanovesicles
Chimeric antigen receptors (CARs) are synthesized membrane proteins that enable lymphocytes to recognize and respond to the specific antigens of target cells. Despite the impressive efficacy of CAR-T cell therapy in treating B-cell lymphoma or leukem.....»»
Using adavosertib-encapsulated MOFs for p53-mutated gallbladder cancer treatment via synthetic lethality
Since the revelation of poly(ADP-ribose) polymerase (PARP) inhibitors and their remarkable results in the treatment of BRCA1/2 mutant cancers, synthetic lethality (SL) in antitumor therapy has attracted increasing attention. SL is a phenomenon in whi.....»»