Possible cause of male infertility linked to structural protein
Mature spermatozoa are characterized by a head, midpiece and a long tail for locomotion. Now, researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Unit "Life & Health" at the University of Bonn have found that a loss.....»»
New nanoparticle delivery method targets sickle cell mutations in bone marrow
Current gene therapies to treat sickle cell disease are complex, time-consuming, and are sometimes linked to serious side effects like infertility or blood cancer. To address these challenges, Johns Hopkins researchers have developed special nanopart.....»»
Discovery of a tRNA modification enzyme that also acts on nucleosides
The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»
Can doomscrolling trigger an existential crisis?
In a world-first study on the impact of doomscrolling from an existential perspective, Flinders University researchers warn that habitual checking of disturbing stories on social media is linked with changes to how we view humankind and the meaning o.....»»
Researchers identify structural characteristics of newly emerged SARS-CoV-2 variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to adapt to the herd immunity background and evolve into numerous sub-variants......»»
One more way to die: Tremors when Vesuvius erupted collapsed shelter walls
Two male skeletons showed signs of severe fracture and trauma injuries. Enlarge / Two skeletons found in the ruins of a Pompeii building may have been crushed by wall collapses triggered by earthquakes. (credit: Pompeii Archaeolo.....»»
Almond genome study paves way for improved breeding strategies
A recent study has unlocked the genetic complexities of almonds, highlighting a significant degree of heterozygosity and the influence of structural variants on gene expression. The research rigorously delineates allele-specific expression patterns,.....»»
Modular design: New insights into protein factories in human mitochondria
The "power plants" of living cells, the mitochondria, probably evolved through endosymbiosis: A bacterium migrated into a primordial cell and eventually developed into an organelle that provides the cell with energy, among other things. Mitochondria.....»»
Snakes on a plate: Pythons touted as protein alternative
In a warehouse in the lush humid farmlands of central Thailand, thousands of pythons lie coiled in containers, rearing and striking at the glass as people pass by......»»
Lab develops smallest free-floating bubbles for medical imaging
Bioengineering researchers at Rice University have developed ultrasmall, stable gas-filled protein nanostructures that could revolutionize ultrasound imaging and drug delivery......»»
Restructuring middle managers—findings from a case study of a major bank
Middle managers play an important role in an organization undergoing structural change. They are the ones who must implement the changes, but conversely, as employees, they will be subject to the very changes they put in place. This can often put the.....»»
Novel protein found to inhibit activity of CRISPR-Cas system
In a study published in Nature on July 3, researchers from the Institute of Biophysics of the Chinese Academy of Sciences and the University of Toronto, Canada, discovered a novel anti-CRISPR protein called AcrIF25, which inhibits the activity of the.....»»
Opening the right doors: New work reveals "jumping gene" control mechanisms
International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents t.....»»
Team investigates chemical modifications to gain deeper insights into genetic regulation mechanisms
University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation, according to the paper, "Drosophila.....»»
Summertime Depression Could Be a Type of Seasonal Affective Disorder
Heat and mood are closely linked, which may explain summertime depression—and how to treat it.....»»
Unexpected phage protein function discovered in bacteria battle
An unexpected find has enabled important progress to be made in the battle against harmful bacteria. An international team of researchers, led by Professor Peter Fineran from the University of Otago, investigated a particular protein used by bacteria.....»»
Researchers listen to the hearts of bats in flight
Researchers from Konstanz have measured the heart rate of bats over several days in the wild, including complete flights—the first time this has been done for a bat species. To record the heart rate of male common noctule bats during flight, the sc.....»»
Tensor-force effects on nuclear matter in relativistic ab initio theory
Tensor force is a crucial ingredient of the nucleon-nucleon (NN) interaction, and has an important impact on the structural and dynamical properties of the nuclear many-body system. Many efforts have been devoted to studying the influence of the tens.....»»
New weight-loss and diabetes drugs linked to lower risk of 10 cancers
For diabetes patients, GLP-1 drugs linked to lower cancer risks compared to insulin. Enlarge / Ozempic is a GLP-1 drug for adults with type 2 diabetes. (credit: Getty | Steve Christo) For patients with Type 2 diabetes, t.....»»
Diversity in typhoid bacteria linked to higher mortality rates
Worldwide, 20% of the bacterial strains that cause typhoid fever have genetic variations in their external layer, called Vi capsule, that provide higher virulence, higher infectivity and high antibiotic resistance, Cornell researchers have discovered.....»»
Intracellular mechanisms shown to promote spread of deadly bacterial infection
Northwestern Medicine investigators have discovered novel protein mechanisms that promote the rapid spread of Vibrio vulnificus, a rare but lethal bacteria that can cause vibriosis and sepsis, according to findings published in the Proceedings of the.....»»