Oral peptides: A new era in drug development
For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require specificity for particular pr.....»»
Researchers identify new tools for anti-Acinetobacter drug development and AMR preparedness
University of Liverpool researchers have engineered a library of strains that can be used to develop new antibacterial compounds to help address antimicrobial resistance (AMR) in Acinetobacter baumannii bacteria......»»
Researcher examines model to foster just and equitable youth engagement in residential facilities
Recent research by Andrew Nalani, a faculty member at Vanderbilt Peabody College of education and human development, examines the viewpoints of youth care workers in juvenile residential facilities and their desires for fostering more just and equita.....»»
Legislation to protect fish in Brazil could have opposite effect
A new law aimed at the protection of migratory fish in Brazil's Pantanal wetlands will harm thousands of local and Indigenous fishers, and puts the environment at greater risk from infrastructure development, finds a new study by a UCL researcher and.....»»
Biomolecules inside living cells can now be seen with infrared light thanks to new method
To accelerate biotechnology innovations, such as the development of lifesaving drug therapies, scientists strive to develop faster, more quantitative and more widely available ways to observe biomolecules in living cells......»»
Scientists learn how to drug wily class of disease-causing enzymes
UCSF scientists have discovered how to target a class of molecular switches called GTPases that are involved in a myriad of diseases from Parkinson's to cancer and have long been thought to be "undruggable.".....»»
Colombian court orders Escobar"s hippos to be hunted
A Colombian court on Friday called for the hunting of hippos, introduced to the country in the 1980s by drug kingpin Pablo Escobar......»»
ADHD med shortages push DEA to up drug allotment by 23.5%
The DEA's quota increase is for Vyvanse and its generic forms. Enlarge (credit: Getty | George Frey) While supplies of Adderall and its generic versions are finally recovering after a yearslong shortage, the Drug Enforce.....»»
Global experts present early-stage recommendations for nanomedicine development
They're tiny drug-delivery systems 1,000 times smaller than a human hair, but while nanomedicines have long been hailed as the future for treating debilitating and life-threatening diseases, their journey from lab to patient has many challenges......»»
A review of humanity"s planned expansion between the Earth and the moon
Between low Earth orbit and the moon, there is a region of space measuring 384,400 km (238,855 mi) wide known as Cislunar space. In the coming decades, multiple space agencies will send missions to this region to support the development of infrastruc.....»»
Algorithm maps protein degradation patterns to improve infection diagnosis and treatment
Peptides are small fragments of proteins, mainly found in the skin and mucous membranes. Some peptides act as a barrier, protecting the body against infections by fighting off microorganisms like bacteria, viruses, and other pathogens, while others p.....»»
An ecological history of resilience and rewilding of a tall forest in southern Italy
Human disturbance has altered the integrity and functionality of forests throughout the globe, with the greatest impact on regions characterized by historical human cultural development and long-term natural resource exploitation. This is the case in.....»»
Revenera OSS Inspector enables developers to assess open source software risks
Revenera announced OSS Inspector, a comprehensive, time-efficient approach to open source software (OSS) management. The Revenera OSS Inspector plugin enables developers using IntelliJ IDEA, an integrated development environment (IDE), to examine, wi.....»»
Novel glass-forming liquid electrolyte shows glass transition across broad range
As the world shifts towards a more sustainable future, the development of advanced electrochemical devices, such as rechargeable batteries with higher energy densities and efficient electrodeposition capabilities, has become increasingly crucial. In.....»»
Researchers explore key interaction sites and pathways in ammonia capture
The design and development of high-performance materials are crucial for efficient ammonia capture. Generally, these materials are characterized by abundant ammonia adsorption sites and rapid ammonia transport channels, enabling the effective capture.....»»
Miscategorization fuels discrimination within organizations and workplaces, say researcher
How does discrimination arise? A new paper by Muhammed Alperen Yasar, Ph.D. student at Ca' Foscari University of Venice and Paris I Pantheon-Sorbonne University offers valuable insights into the development of discriminatory behaviors in organization.....»»
Game developers are waiting for Godot on iPad
Developers could soon have a new option for making games on an iPad, with a port of the game engine Godot getting close to an initial test release.Godot on iPadApple's Swift Playgrounds is an entryway to game and app development on iPad, which can al.....»»
Stellantis changes Jeep N.A. chief after 9 months
Ram brand executive Bob Broderdorf succeeds Bill Peffer as head of Jeep in North America, while Peffer replaces Phil Langley as head of dealer network development......»»
Color-changing, self-healing hydrogel microparticles: A smart solution for advanced wound care
Chronic diabetic wounds are prevalent in patients and are difficult to heal, presenting a significant medical challenge. The development of multifunctional hydrogel dressings with a well-designed morphology and structure can enhance their flexibility.....»»
Exploring peptide clumping for improved drug and material solutions
Scientists from China have investigated how short peptide chains aggregate together in order to deepen our understanding of the process which is crucial for drug stability and material development......»»
Copper-based catalyst paves the way for sustainable ammonia production
Ammonia plays a critical role in food production and industrial development, with a global market size of approximately 175 million metric tons and a market value of $67 billion. Likewise, it is a high-energy-density carrier, making it a key player i.....»»