Nucleoside analogs for messenger RNA metabolic labeling and sequencing
High-throughput RNA-sequencing (RNA-seq) is widely used to profile global cellular gene expression and gain insights into cellular biological processes; however, effectively tracking dynamic changes in cellular mRNA expression remains a challenge. Be.....»»
Kariko, Weissman win Nobel for mRNA COVID vaccines
Katalin Kariko and Drew Weissman won the Nobel Medicine Prize on Monday for work on messenger RNA (mRNA) technology that paved the way for groundbreaking COVID-19 vaccines......»»
Unraveling metabolic processes spanning from subcellular organelles to complex tissues
Metabolism serves as a direct reflection of biological functions and pathological conditions. Throughout the years, biologists and doctors have been delving into the intricate metabolic mechanisms underlying physiological processes and disease states.....»»
Yelp sues Texas to defend its labeling of crisis pregnancy centers
Yelp is suing Texas to ensure it can continue to tell users that crisis pregnancy centers listed on its site do not provide abortions or abortion referrals, opening a new front in the fight between states and the tech industry over abortion restricti.....»»
Everything You Need to Know About Getting Your Genome Sequenced
DNA sequencing can assess your risk of developing certain diseases. It could even help provide medicines personalized to your genes one day. Governments want you to get involved......»»
New nanopore tech for quicker, more thorough mRNA quality checks
Researchers at The University of Queensland are harnessing the latest sequencing technology developed by UK-based biotech Oxford Nanopore Technologies to analyze mRNA vaccines and therapies......»»
Disrupting a core metabolic process in T cells may improve their therapeutic efficacy
In exploring an aspect of how killer T cells generate the raw materials required for their proliferation, a Ludwig Cancer Research study has uncovered an unexpected link between the immune cells' metabolism, regulation of gene expression, persistence.....»»
Dingoes found to have more harmful mutations than most inbred dog breeds
Genome sequencing comparisons with wolves, strays and dogs across the world has found Australia's dingoes have the highest loads of harmful mutations—and diversity levels that are 36% lower than the most inbred dogs......»»
How bats evolved to avoid cancer
A new paper titled "Long-read sequencing reveals rapid evolution of immunity and cancer-related genes in bats" in Genome Biology and Evolution shows that rapid evolution in bats may account for the animals' extraordinary ability to both host and surv.....»»
WhatsApp is finally launching a beta app for the iPad
The popular instant messenger WhatsApp was developed with smartphones in mind. However, over the years, the app has become available for computers, too – with a brand new version for macOS released last month. Now WhatsApp is finally coming to the.....»»
RNA has been recovered from an extinct species for the first time
A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptom.....»»
I tried a lifesaving gadget that’s going to transform your phone
I tried the Motorola Defy with the Bullitt Satellite Messenger app, a pairing that could save your life in an emergency when you don't have cellular service......»»
Accelerating knowledge exchange in African biodiversity genomics and bioinformatics
Since its inception in 2021, the African BioGenome Project (AfricaBP), has made significant gains towards its ambitious goal of sequencing 100,000 endemic African species within the next 10 years. Recently, AfricaBP reported the successful implementa.....»»
Requests via Facebook Messenger lead to hijacked business accounts
Hijackers of Facebook business accounts are relying on fake business inquiries and threats of page/account suspension to trick targets into downloading password-stealing malware. Examples of phishing messages. (Source: Guardio Labs) The campaign Hija.....»»
"Invisible" cell types and gene expression revealed with sequencing data analysis improvement
In 2018, researchers in the Caltech laboratory of Yuki Oka, professor of biology and Heritage Medical Research Institute Investigator, made a major discovery: They identified a type of neuron, or brain cell, that mediates thirst satiation. But they w.....»»
Refining biome labeling for microbial community samples
In a study published in the journal Environmental Science and Ecotechnology, researchers from Huazhong University of Science and Technology have introduced "Meta-Sorter," an AI-based method that leverages neural networks and transfer learning to sign.....»»
Milk analysis reveals "invisible" disease in dairy cows
Researchers have developed a new method of detecting a metabolic disease that affects dairy cows after calving. The aim is to determine whether cows are at risk of contracting the disease before they actually become sick......»»
Study provides evidence for hidden diversity within Hydnoraceae
Researchers from the Wuhan Botanical Garden of the Chinese Academy of Sciences (CAS) have conducted a phylogenetic analysis of Hydnora plants in the family Hydnoraceae through plastid genome sequencing, assembly and annotation after extensive data qu.....»»
A DNA assembly kit to unlock the CRISPR-Cas9 potential for metabolic engineering
The clustered regularly interspaced short palindrome repeats (CRISPR) and Crispr-associated protein 9 (CRISPR/Cas9) is now a well-known, revolutionary method to engineer microbial cells......»»
Facebook Messenger E2E encryption rolling out to millions more; to all by year end
Facebook Messenger E2E encryption has been available to some users for some years now, but a full rollout has taken longer than expected. The company says it is now expanding end-to-end encrypted messaging to “millions” more people, and promis.....»»
A peptide that can cross the blood-brain barrier
In a paper published in Science China Materials, a research team reports on a novel tetrapeptide, GFFY, which is capable of efficiently crossing the blood-brain barrier (BBB). The tetrapeptide is highly versatile in covalent labeling with Cy5.5 and t.....»»