Novel coronaviruses are riskiest for spillover
In the past decade, scientists have described hundreds of novel viruses with the potential to pass between wildlife and humans. But how can they know which are riskiest for spillover and therefore which to prioritize for further surveillance in peopl.....»»
The threat from Thwaites: The retreat of Antarctica"s riskiest glacier
Antarctica's Thwaites Glacier is retreating rapidly as a warming ocean slowly erases its ice from below, leading to a faster flow, more fracturing and a threat of collapse, according to an international team of scientists. The glacier currently contr.....»»
Researchers develop platform to screen for new class of coronavirus antiviral compounds
A new high-throughput platform screens for drug compounds that hit a target found in human and bat coronaviruses and could be used to develop future treatments......»»
Researchers develop platform to screen for new class of coronavirus antiviral compounds
Researchers investigating ways to develop a novel class of antiviral drugs to treat coronaviruses, including SARS-CoV-2, which causes COVID-19, have developed a platform that can rapidly screen thousands of compounds to identify potential candidates......»»
Beamlines cast light on SARS-CoV-2, emerging variants and vaccines that will stop them
Ultrabright light from the Advanced Photon Source continues to illuminate mysteries around coronaviruses and shape the vaccines and therapeutics protecting us against variants of concern......»»
A longer-lasting COVID vaccine? New study points the way
Researchers have identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses. The findings suggest that a component of this protein, called viral polymerase, could potent.....»»
Scientists find SARS-CoV-2-related coronaviruses in Cambodian bats from 2010
Scientists have identified coronaviruses closely related to SARS-CoV-2 from two bats sampled in Cambodia more than a decade ago......»»
Exposure to harmless coronaviruses boosts SARS-CoV-2 immunity, study shows
Infections with the novel coronavirus and vaccination lead to strong antibody responses against SARS-CoV-2. Immune responses to other human coronaviruses, which mostly only cause harmless colds, also provide some protection against SARS-CoV-2. This c.....»»
ESA"s riskiest flyby
The chance that ESA's Solar Orbiter spacecraft will encounter space debris during its upcoming Earth flyby is very, very low. However, the risk is not zero and is greater than any other flyby ESA has performed. That there is this risk at all highligh.....»»
Rodents could be asymptomatic carriers of SARS-like coronaviruses, study suggests
Some ancestral rodents likely had repeated infections with SARS-like coronaviruses, leading them to acquire tolerance or resistance to the pathogens, according to new research. This raises the possibility that modern rodents may be reservoirs of SARS.....»»
Solar Orbiter to perform its riskiest flyby before heading to the sun
This week, the Solar Orbiter will perform its riskiest flyby, dipping through the ring of space debris that surrounds Earth before whipping away toward the sun......»»
Rodents could be asymptomatic carriers of SARS-like coronaviruses, study suggests
Some ancestral rodents likely had repeated infections with SARS-like coronaviruses, leading them to acquire tolerance or resistance to the pathogens, according to new research publishing November 18th in PLOS Computational Biology by Sean King and Mo.....»»
Economists warn spillover effect of China economic slowdown
China's third-quarter economic growth numbers slowed more than expected to 4.9% from the same period last year, falling short of the 5.2% forecasted by a Reuters poll, but the growth has not yet bottomed, said economists......»»
When organoids meet coronaviruses
Researchers from the group of Hans Clevers in collaboration with the group of Bart Haagmans (Erasmus MC) established an organoid biobank to search for the genes that are essential for the spreading of a SARS-CoV2 infection. Their study was published.....»»
New technique boosts cryo-electron microscopy clarity, safety
When scientists needed to visualize the structure of the spike protein, which coronaviruses use to infiltrate human cells, they turned to cryo-electron microscopy. One of the most powerful imaging tools in a researcher's arsenal, cryo-electron micros.....»»
Understanding pathogen tolerance in wild animals key to pandemic preparedness
A new multidisciplinary research framework is needed to explore links between evolved tolerance to pathogens and their spillover into humans, scientists write today in the journal eLife......»»
Mammal biodiversity shapes disease risk
To predict the spillover of pathogens from wildlife to humans and limit future pandemics, it is important to understand where wildlife disease risk is highest. A team of researchers, led by Wageningen University & Research (WUR) in The Netherlands, r.....»»
COVID-causing coronavirus following predictable mutational footsteps
New research has shown that the mutations arising in the COVID-19-causing SARS-CoV-2 virus seem to run in the family -- or at least the genus of coronaviruses most dangerous to humans. After comparing the early evolution of SARS-CoV-2 against that of.....»»
Study ties milder COVID-19 symptoms to prior run-ins with other coronaviruses
In COVID-19 patients whose symptoms were mild, researchers found that they were more likely than sicker patients to have signs of prior infection by similar, less virulent coronaviruses......»»
New vaccine blocks COVID-19 and variants, plus other coronaviruses
A potential new vaccine has proven effective in protecting monkeys and mice from a variety of coronavirus infections -- including SARS-CoV-2 as well as the original SARS-CoV-1 and related bat coronaviruses that could potentially cause the next pandem.....»»
Researchers analyze the host origins of SARS-CoV-2 and other coronaviruses
Coronavirus (CoVs) infection in animals and humans is not new. The earliest papers in the scientific literature of coronavirus infection date to 1966. However, prior to SARS-CoV, MERS-CoV, and SARS-CoV-2, very little attention had been paid to corona.....»»