New route to the synthesis of P-chiral compounds
Chiral phosphines are one of the most commonly used ligands in assymetric metal catalysis for the synthesis of various useful drugs and pharmaceuticals. Have you ever wondered how to obtain them? Most of the so-called chiral phosphines are C-stereoge.....»»
Adding to the story of ancient human migration: Evidence of early maritime activities in Indonesia"s Tanimbar islands
New evidence of human occupation in southeast Indonesia dating back 42,000 years offers fresh clues about the route taken by some of the first humans to arrive in our region, according to a study from The Australian National University (ANU). The res.....»»
Discovery of a tRNA modification enzyme that also acts on nucleosides
The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»
Bubbling with benefits: Hydrogen nanobubbles boost tomato antioxidants
Tomatoes are a key source of antioxidants, crucial for human health as they help combat oxidative stress. Traditional irrigation methods often fail to significantly enhance these beneficial compounds in crops. Hydrogen, known for its unique antioxida.....»»
Organic compounds show promise as cheaper alternatives to metal photocatalysts
Organic compounds that can be sustainably and affordably mass-produced show promise as replacements for expensive metal photocatalysts, according to a new report published July 17......»»
Chemists develop modular approach for creating important class of pharmaceutical compounds
Chemists at the National University of Singapore (NUS) have developed a modular approach to create 1,2-arylheteroaryl ethanes, a class of compounds important for drug discovery and pharmaceutical development, using fundamental feedstock chemicals suc.....»»
New tool can predict bitterness in foods without prior knowledge of their chemical structures
BitterMasS, a novel tool utilizing mass spectrometry, promises advancements in predicting bitterness in compounds. Developed through interdisciplinary collaboration, it offers enhanced precision and efficiency compared to traditional methods, with wi.....»»
New method for simultaneous high-resolution measurement of chiral molecules
Researchers have developed a new method for precisely analyzing molecules' chirality. This method, known as cavity-enhanced chiral eigenmode (CECEM) spectroscopy, offers several advantages over existing techniques, including the ability to simultaneo.....»»
Research team develops light-activated compounds to treat neuropathic pain
Light can be used to activate drugs in specific parts of the body through photopharmacology. This innovative approach involves modifying the chemical structure of a drug by adding a light-activated molecular switch, such as azobenzene. This allows th.....»»
New geological dating techniques place first European hominids in Iberian Peninsula 1.3 million years ago
One of the most important controversies about human evolution and expansion is when and by what route the first hominids arrived in Europe from the African continent. Now, geological dating techniques at the Orce sites (Baza basin, Granada) place the.....»»
A comprehensive derivative synthesis method for development of new antimicrobial drugs
Efforts to combat the increasing threat of drug-resistant bacteria are being assisted by a new approach for streamlining the search for antimicrobial drug candidates, pioneered by researchers at Hokkaido University, led by Assistant Professor Kazuki.....»»
A better way to make RNA drugs: Enzymatic synthesis method expands capabilities while eliminating toxic byproducts
While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis. RNA therapies offer many advantages over tra.....»»
A black bear may pave the way for new wildlife crossings
A bear taking the scenic route around Southern California may help researchers learn how wild animals cross freeways to get from one habitat to the next—and how they might be kept out of your backyard......»»
Astronomers suggest up to 60% of near-Earth objects could be dark comets
Up to 60% of near-Earth objects could be dark comets, mysterious asteroids that orbit the sun in our solar system that likely contain or previously contained ice and could have been one route for delivering water to Earth, according to a University o.....»»
Unlocking the potential of anti-perovskites through a convenient one-step synthesis route
Although perovskites have attracted a lot of attention lately, anti-perovskites hold just as much potential as functional materials. Bearing a similar crystal structure to perovskites but with an inverted electrical configuration, anti-perovskites ex.....»»
First set of rational design principles for chaotropic membrane transporters
The challenge of internalizing impermeable molecules into cells persists in drug development, particularly concerning water-soluble bioactive compounds that cannot diffuse across the cell membrane. To overcome this problem, various artificial transpo.....»»
Photoenzymatic synthesis achieves efficient oxidation of fatty acids
A research team designed and built a photoenzymatic cascade by combining photochemical water oxidation/O2 reduction with P450 peroxygenase catalysis to achieve efficient visible-light-driven oxidation of a range of fatty acids (C12-C20), leading to p.....»»
Scientists investigate fast reaction dynamics in synthetic molecules immobilized in porous protein cages
Immobilizing small synthetic molecules inside protein crystals proves to be a promising avenue for studying intermediate compounds formed during chemical reactions, report scientists from Tokyo Tech. By integrating this method with time-resolved seri.....»»
Why the reliable dipstick is sliding into obsolescence
It seems counterintuitive: Replacing a simple, trusty, low-tech part with costly sensors to measure oil. But this is why some automakers are going that route......»»
Starlings" migratory behavior found to be inherited, not learned
Young, naïve starlings are looking for their wintering grounds independently of experienced conspecifics. Starlings are highly social birds throughout the year, but this does not mean that they copy the migration route from each other......»»
Researchers demonstrate economical process for the synthesis and purification of ionic liquids
Recently, a team of researchers from Pohang University of Science and Technology (POSTECH), the Korea Research Institute of Chemical Technology, and Chonnam National University has developed a technique to separate well-mixed mixtures......»»