New route to the synthesis of P-chiral compounds
Chiral phosphines are one of the most commonly used ligands in assymetric metal catalysis for the synthesis of various useful drugs and pharmaceuticals. Have you ever wondered how to obtain them? Most of the so-called chiral phosphines are C-stereoge.....»»
Uncovering the unique roles of Exportin-5 in RNA export within Drosophila cells
Eukaryotic cells are complex biological units, each with multiple membrane-bound compartments. These cells use specialized mechanisms to export biomolecules from their synthesis site to where they function......»»
Glitch in protein synthesis could affect tumor growth
During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together of amino acids—the building blocks of proteins. As the translation machinery carouses along the string of nucleotides that m.....»»
Novel design strategy advances discovery of metal-organic frameworks
An innovative strategy, known as the "Up-Down Approach," has the potential to dramatically accelerate the creation of metal-organic frameworks (MOFs). The paper is published in the journal Nature Synthesis......»»
Expanding click chemistry: An eco-friendly conversion process for the synthesis of sulfonyl fluorides
For the first time, thiols and disulfides have been converted into sulfonyl fluorides using SHC5 and KF, expanding click chemistry with high efficiency and low environmental impact......»»
Chemists achieve PFAS-free synthesis of fluorinated pharmaceutical and agrochemical compounds
Chemists at the University of Amsterdam have developed a method to furnish a range of molecules with a trifluoromethyl group attached to a sulfur, nitrogen or oxygen atom. Their procedure, which is published in Science, avoids the use of PFAS reagent.....»»
Study: Plasmonic copper nanowires boost nitrate reduction efficiency
The electrocatalytic nitrate reduction reaction (NO3RR) has attracted the attention of researchers for its significant value in ammonia synthesis and effluent treatment. Plasmon-assisted electrocatalysis provides a powerful strategy for efficient con.....»»
Chiral molecule research achieves near-complete separation in quantum states
In a study titled "Near-complete chiral selection in rotational quantum states" published in Nature Communications, the Controlled Molecules Group from the Molecular Physics Department of the Fritz Haber Institute has made a significant leap forward.....»»
Protein mutant stability can be inferred from AI-predicted structures
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»
Compounds from nucleic acids in food show anticancer effects
When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by Osaka Metropolitan University Associate Professor A.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Nanotubes boost: Liquid-phase synthesis unlocks efficient production
Single-walled carbon nanotubes (SWCNTs) are known for their remarkable properties, which make them essential in many advanced technologies. Yet, creating these nanotubes efficiently and on a large scale has been a persistent challenge......»»
From leaf to cup: The essential role of magnesium in tea plant metabolism
Magnesium plays a vital role in the growth and quality of tea plants, influencing key processes such as photosynthesis and the synthesis of important metabolites. However, tea plants often suffer from magnesium deficiency due to factors like poor soi.....»»
New "chiral vortex" of light allows chemists to "see" molecules through the mirror
An entirely new structure of light is helping to measure chirality in molecules more accurately and robustly than ever before, in a major potential step for the pharmaceutical industry......»»
AI accelerates discovery of next-gen polymers
Nylon, Teflon, Kevlar. These are just a few familiar polymers—large-molecule chemical compounds—that have changed the world. From Teflon-coated frying pans to 3D printing, polymers are vital to creating the systems that make the world function be.....»»
Image: Juice snaps moon en route to Earth
During the first step of humankind's first-ever lunar-Earth flyby, ESA's Jupiter Icy Moons Explorer (Juice) mission captured this stunning view of the moon......»»
New software tool aims to reduce reliance on animal testing
In recent years, machine learning models have become increasingly popular for risk assessment of chemical compounds. However, they are often considered "black boxes" due to their lack of transparency, leading to skepticism among toxicologists and reg.....»»
A new reaction to enhance aromatic ketone use in chemical synthesis
Aromatic ketones have long been valuable intermediates in chemical synthesis, particularly in cross-coupling reactions where different chemical entities are combined to form new compounds. For instance, a process called deacylative cross-coupling rem.....»»
Mechanistic insights on SSZ-13 zeolite in catalytic dimethyl ether carbonylation
Dimethyl ether (DME) carbonylation to methyl acetate (MA) is one of the crucial steps in an indirect synthesis route of ethanol from syngas. SSZ-13 zeolite, with a typical topology of CHA, characterized by its 8-membered ring (8-MR) channels, has sho.....»»
New twist on synthesis technique promises sustainable manufacturing
James Tour's lab at Rice University has developed a new method known as flash-within-flash Joule heating (FWF) that could transform the synthesis of high-quality solid-state materials, offering a cleaner, faster and more sustainable manufacturing pro.....»»
Massachusetts governor signs law phasing out toxic PFAS in firefighters" gear
Massachusetts Gov. Maura Healey signed into law Thursday a bill that would phase out the use of PFAS, a group of toxic industrial compounds, in firefighters' protective gear......»»