New nanoparticles can perform gene-editing in the lungs
Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins......»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
How iron and metabolic constraints can aid gene discovery for photosynthesis and biofuel production
The single-cell green alga Chromochloris zofingiensis is an emerging model organism for photosynthesis and metabolism research. Previous research has shown that with the addition of glucose, Chromochloris zofingiensis shuts off photosynthesis, rerout.....»»
Naked mole-rat found to have lost infection-resistant proteins
Scientists have found that the naked mole-rat—an underground rodent that lives up to 40 years—has lost a number of CD1 functional genes. The CD1 gene family in mammals is responsible for protein synthesis that protects the body against infectious.....»»
Compact "gene scissors" enable effective genome editing, may offer future treatment of high cholesterol gene defect
CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissors" but is much smaller and thus easier to transport into cells......»»
Better than blood tests? Nanoparticle potential found for assessing kidneys
In a study published July 29 in Advanced Materials, University of Texas at Dallas researchers found that X-rays of the kidneys using gold nanoparticles as a contrast agent might be more accurate in detecting kidney disease than standard laboratory bl.....»»
Magnetic micro spinbots can perform ultraprecise surface polishing and cleaning
A research team has unveiled an innovative technology for ultraprecision surface polishing and cleaning using simultaneously operating magnetic micro spinbots. These tiny robots, capable of nanometer-scale contaminant removal and polishing, offer a l.....»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»
Analysis of heterostructures for spintronics shows how two desired quantum-physical effects reinforce each other
Spintronics uses the spins of electrons to perform logic operations or store information. Ideally, spintronic devices could operate faster and more energy-efficiently than conventional semiconductor devices. However, it is still difficult to create a.....»»
Team develops gene editing strategy for macroalgae Neopyropia
Neopyropia is an important economic macroalga and is one of the main macroalgae cultivation species in China, Japan, South Korea and other countries. As a critical juncture in the evolution of photosynthetic organisms, red algae to which Neopyropia b.....»»
Visible-light-antenna ligand enhances samarium-catalyzed reactions
Samarium (Sm), a rare earth metal, is important to organic chemists because of the ability of its divalent compounds to efficiently perform single-electron transfer reductions......»»
Study reveals that future climate change may reduce the Amazon rainforest"s ability to act as a carbon sink
The Amazon, often called the "lungs of the planet," is the world's largest tropical forest, playing a crucial role in the global climate system due to its vast carbon storage. While it is typically warm and humid all year round, continued climate cha.....»»
Gene-based model predicts when Japan"s cherry buds awake from dormancy
Japan in spring is famous for its cherry blossoms, or sakura, which begin flowering in the southern region of Kyushu and blaze upwards to the remote north of Hokkaido. The most abundant cherry tree cultivar, Somei Yoshino, is the iconic symbol of spr.....»»
Poor indoor air quality isn"t just making us sick. It"s also polluting our cities
According to the World Health Organization (WHO), air pollution is one of the greatest environmental health challenges that we face today. Various studies have shown that in addition to the lungs, it affects essential organs like the heart and brain,.....»»
Silencing in action: How cells "repress" genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of "cryptic" genomic regions, including ancient viral sequences......»»
Polaris Dawn Astronauts Perform First Private Space Walk in a Stellar Success for SpaceX
The world’s first commercial space walk, performed by billionaire Jared Isaacman and SpaceX engineer Sarah Gillis, tested new technology and was practically flawless.....»»
Researchers test ChatGPT, other AI models against real-world students
William Hersh, M.D., who has taught generations of medical and clinical informatics students at Oregon Health & Science University, found himself curious about the growing influence of artificial intelligence. He wondered how AI would perform in his.....»»
Virtual laboratory allows scientists to simulate specific decreases in gene activity
Imagine you're looking at millions upon millions of mysterious genetic mutations. With CRISPR gene-editing technology, a select few of these mutations might have therapeutic potential. However, proving it would mean many thousands of hours of lab wor.....»»
How to create a pivot table in Excel to slice and dice your data
Here's how to create a pivot table in Excel to slice and dice your data, letting you perform in-depth analyses and spot important trends. If you're new to pivot tables, this guide will get you started with a minimum of fuss......»»
EchoStrike: Generate undetectable reverse shells, perform process injection
EchoStrike is an open-source tool designed to generate undetectable reverse shells and execute process injection on Windows systems. “EchoStrike allows you to generate binaries that, when executed, create an undetectable RevShell, which can be.....»»
New method to break down forever chemicals uses nanoparticles and ultrasound
What do firefighting foam, non-stick cookware, water-repellent textiles and pesticides all have in common? They all contain per- and polyfluoroalkyl substances, or PFAS—human-made chemicals that don't break down naturally. It's no wonder, then, tha.....»»