New mechanism proposed for why some psychedelics act as antidepressants
We know what receptors they bind, but where they bind them might matter, too. Enlarge (credit: VICTOR de SCHWANBERG/SCIENCE PHOTO LIBRARY) Psychedelic drugs are often used for entertainment purposes. But there have been.....»»
iPhone 16 won"t be compelling and Apple will get hurt because of it, says Kuo
Apple's shipments of iPhones may drop by up to 15% because of multiple issues including the iPhone 16 not being a compelling upgrade, according to analyst Ming-Chi Kuo.iPhone 15 Pro MaxReports have proposed that Apple has already started to adjust it.....»»
Apple warns proposed UK law will affect software updates around the world
Apple may leave the UK if required to provide advance notice of product updates. Enlarge Apple is "deeply concerned" that proposed changes to a United Kingdom law could give the UK government unprecedented power to "sec.....»»
Researchers discover molecular mechanism that influences the symmetrical shape of the style
Humans are attracted to symmetry: in our buildings, our gardens, in our potential partners. For plants, the symmetrical shapes of organs are a matter of survival because the form directly impacts the function......»»
To stick or not to stick? Mixed sand columns illuminate design of better materials
Scientists from Tokyo Metropolitan University have been studying the strength and toughness of sand columns made of a mixture of sticky and non-sticky grains. They have uncovered the mechanism behind how the strength changes as grains are mixed in di.....»»
Scientists Just Discovered a New Type of Magnetism
In an atomically thin stack of semiconductors, a mechanism unseen in any natural substance causes electrons’ spins to align......»»
New simulation tool advances molecular modeling of biomolecular condensates
A University of Massachusetts Amherst team has made a major advance toward modeling and understanding how intrinsically disordered proteins (IDPs) undergo spontaneous phase separation, an important mechanism of subcellular organization that underlies.....»»
Nearly 5,000 dealerships send second letter urging Biden to "hit the brakes" on EV push
The second letter comes after nearly 4,000 dealerships in November sent a letter calling on Biden to reconsider the proposed regulations, which they argue would mandate an unrealistic shift to battery-electric vehicles in the U.S......»»
Ancient "relaxant-inflammatory" mechanism gets sponges moving
Did you know that sponges can move? While not exactly the champions of underwater acrobatics, sponges exhibit coordinated movements—despite not having muscles or neurons......»»
Team unravels activation mechanism of a protein that combats bacteria
The human immune system is constantly fending off a wide range of invaders—a feat that requires a diverse array of cellular troops and molecular weaponry. Although a great deal is already known about immune defense cells and the strategies they emp.....»»
OpenWrt, now 20 years old, is crafting its own future-proof reference hardware
There are, as you might expect, a few disagreements about what's most important. Enlarge / Failing an image of the proposed reference hardware by the OpenWrt group, let us gaze upon where this all started: inside a device that tr.....»»
Shallow soda lakes show promise as cradles of life on Earth
Charles Darwin proposed that life could have emerged in a "warm little pond" with the right cocktail of chemicals and energy. A study from the University of Washington, published this month in Communications Earth & Environment, reports that a shallo.....»»
Study of gigantism in whales provides clues to genomic mechanism involved in tumor suppression
The functioning of certain regions of a few genes in cetaceans (whales, porpoises and dolphins) may explain why the Blue whale (Balaenoptera musculus) can reach lengths of up to 30 meters—almost 10 m more than a bus—while the Bottlenose dolphin (.....»»
Energy supply in human cells is subject to quality control, researchers discover
Researchers at the University Medical Center Göttingen (UMG) have discovered a new quality control mechanism that regulates energy production in human cells. This process takes place in mitochondria, the power plants of the cell......»»
Chilled-out tadpoles defy climate odds
University of Queensland researchers have discovered a previously unknown mechanism that allows tadpoles in cold environments to mitigate the detrimental effects of ultraviolet (UV) radiation......»»
Why Colombia sees legalizing drugs as the way forward—here"s what"s being proposed
Another drug war has begun in Latin America. The newly elected president of Ecuador, Daniel Noboa, has declared a state of emergency and the military is being used to tackle violence and drug trafficking in a country that is part of the transnational.....»»
California"s water-saving plan slammed as costly, complicated and unrealistic
In a scathing review, advisors to the state Legislature have found that California's proposed regulations for urban water conservation would be costly, overly complicated and difficult to implement......»»
Sharing deepfake porn could lead to lengthy prison time under proposed law
Teen “shouting for change” after fake nude images spread at NJ high school. Enlarge (credit: Georgijevic | E+) The US seems to be getting serious about criminalizing deepfake pornography after teen boys at a New Jers.....»»
Elucidating the biosynthetic mechanism for protoberberine alkaloids from Coptis chinensis
Protoberberine alkaloids are a group of tetracyclic isoquinoline compounds known for their well-established antimicrobial and anti-inflammatory properties. Although protoberberine alkaloids are broadly found in various plant families such as Ranuncul.....»»
Climate change threatens fish supply: Tiny phytoplankton, big consequences
A research team that includes Dr. Angus Atkinson of the Plymouth Marine Laboratory and Dr. Axel Rossberg from Queen Mary University of London has discovered a hidden amplifying mechanism within the ocean's food web. Their findings, published in Natur.....»»
Apple readies Apple Watch Series 9 ban workaround by disabling blood oxygen functionality [U]
The U.S. Customs agency has handed down its decision on whether Apple’s proposed redesign of the Apple Watch Series 9 and Apple Watch Ultra 2 is enough to circumvent infringing on two Masimo patents related to the blood oxygen sensor. In a fili.....»»